标题
Sphingolipids as Regulators of Neuro-Inflammation and NADPH Oxidase 2
作者
关键词
-
出版物
NEUROMOLECULAR MEDICINE
Volume 23, Issue 1, Pages 25-46
出版商
Springer Science and Business Media LLC
发表日期
2021-02-08
DOI
10.1007/s12017-021-08646-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- New Variant Mutation of Glucosylceramidase Beta (GBA) and Early Enzyme Replacement Therapy for Neuronopathic Gaucher Disease: A Case Report and Literature Review
- (2020) Daiji Takajo et al. Iranian Journal of Pediatrics
- Role of 1‐Deoxysphingolipids in docetaxel neurotoxicity
- (2020) Katrin Anne Becker et al. JOURNAL OF NEUROCHEMISTRY
- Lysosomal Ceramide Metabolism Disorders: Implications in Parkinson’s Disease
- (2020) Silvia Paciotti et al. Journal of Clinical Medicine
- Sphingosine 1-Phosphate Receptor 2 Induces Otoprotective Responses to Cisplatin Treatment
- (2020) Wei Wang et al. Cancers
- Modulation of radiation-induced damage of human glomerular endothelial cells by SMPDL3B
- (2020) Alaa Abou Daher et al. FASEB JOURNAL
- Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease
- (2020) Bernadette Breiden et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Multiple Sulfatase Deficiency: A Disease Comprising Mucopolysaccharidosis, Sphingolipidosis, and More Caused by a Defect in Posttranslational Modification
- (2020) Lars Schlotawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer’s Disease
- (2020) Henryk Jęśko et al. MOLECULAR NEUROBIOLOGY
- Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy‐mediated degradation
- (2020) Yaping Wang et al. FASEB JOURNAL
- Upregulating β-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity
- (2020) Oeystein R. Brekk et al. Acta Neuropathologica Communications
- The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders
- (2019) Kinga Czubowicz et al. MOLECULAR NEUROBIOLOGY
- Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons
- (2019) Wenshuo Zhou et al. Emerging Microbes & Infections
- Inhibition of NADPH oxidase by apocynin prevents learning and memory deficits in a mouse Parkinson's disease model
- (2019) Liyan Hou et al. Redox Biology
- Neuroinflammation in frontotemporal dementia
- (2019) Fiona Bright et al. Nature Reviews Neurology
- SMPDL3b modulates insulin receptor signaling in diabetic kidney disease
- (2019) A. Mitrofanova et al. Nature Communications
- Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease
- (2019) Mona Lei et al. JOURNAL OF NEUROSCIENCE
- Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease
- (2018) T. N. Seyfried et al. ASN Neuro
- Acid Sphingomyelinase Down-Regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats
- (2018) Xin Li et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Zika virus infected primary microglia impairs NPCs proliferation and differentiation
- (2018) Jin Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Murine Sialidase Neu3 facilitates GM2 degradation and bypass in mouse model of Tay-Sachs disease
- (2018) Volkan Seyrantepe et al. EXPERIMENTAL NEUROLOGY
- Stimulation of S1PR5 with A-971432, a selective agonist, preserves blood–brain barrier integrity and exerts therapeutic effect in an animal model of Huntington’s disease
- (2018) Alba Di Pardo et al. HUMAN MOLECULAR GENETICS
- Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
- (2018) Emma R. Wilson et al. NEUROBIOLOGY OF DISEASE
- Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide
- (2018) Friederike Zunke et al. NEURON
- Analysis of age-related changes in psychosine metabolism in the human brain
- (2018) Michael S. Marshall et al. PLoS One
- Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis
- (2018) Alexandre Henriques et al. Frontiers in Molecular Neuroscience
- Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer’s disease brain
- (2018) Gaëlle Dominguez et al. Acta Neuropathologica Communications
- Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma
- (2018) Heidi A. Neubauer et al. ONCOGENE
- Zika virus infection modulates the metabolomic profile of microglial cells
- (2018) Fodé Diop et al. PLoS One
- Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress
- (2018) Sungjin Kim et al. Cell Reports
- The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease
- (2018) Alice J. White et al. Frontiers in Neurology
- FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts
- (2017) Jason Newton et al. FASEB JOURNAL
- High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS
- (2017) Maria Blomqvist et al. JOURNAL OF LIPID RESEARCH
- Types A and B Niemann-Pick disease
- (2017) Edward H. Schuchman et al. MOLECULAR GENETICS AND METABOLISM
- Sphingolipids and their metabolism in physiology and disease
- (2017) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation
- (2017) Veit Rothhammer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease
- (2017) Alba Di Pardo et al. Frontiers in Neuroscience
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway: Therapeutic Targets in Autoimmunity and Inflammation
- (2016) Hsing-Chuan Tsai et al. DRUGS
- Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse
- (2016) Michael B. Dinkins et al. JOURNAL OF NEUROSCIENCE
- CNS-accessible Inhibitor of Glucosylceramide Synthase for Substrate Reduction Therapy of Neuronopathic Gaucher Disease
- (2016) John Marshall et al. MOLECULAR THERAPY
- Lysosomal trafficking defects link Parkinson's disease with Gaucher's disease
- (2016) Yvette C. Wong et al. MOVEMENT DISORDERS
- Fingolimod: A Disease-Modifier Drug in a Mouse Model of Amyotrophic Lateral Sclerosis
- (2016) Rosa Luisa Potenza et al. Neurotherapeutics
- Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking
- (2016) Megan M. Young et al. Cell Reports
- Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death: implications for otoprotective therapy
- (2016) Deron R. Herr et al. Scientific Reports
- Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models
- (2015) Qingshan Wang et al. BRAIN
- Autoimmune Encephalitis and Its Relation to Infection
- (2015) Arun Venkatesan et al. Current Neurology and Neuroscience Reports
- Elevation of plasma 1-deoxy-sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy?
- (2015) M. F. Dohrn et al. EUROPEAN JOURNAL OF NEUROLOGY
- Neurotoxic 1-deoxysphingolipids and paclitaxel-induced peripheral neuropathy
- (2015) Rita Kramer et al. FASEB JOURNAL
- HSAN1 mutations in serine palmitoyltransferase reveal a close structure–function–phenotype relationship
- (2015) Heiko Bode et al. HUMAN MOLECULAR GENETICS
- Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTRup-regulation and astrocyte-mediated inflammation
- (2015) Andrés Miguez et al. HUMAN MOLECULAR GENETICS
- Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice
- (2015) Andreas Bickert et al. JOURNAL OF LIPID RESEARCH
- Frontotemporal dementia
- (2015) Jee Bang et al. LANCET
- Unknown
- (2015) Karen Ashe et al. MOLECULAR MEDICINE
- HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation
- (2015) Victoria A. Blaho et al. NATURE
- Novel HSAN1 Mutation in Serine Palmitoyltransferase Resides at a Putative Phosphorylation Site That Is Involved in Regulating Substrate Specificity
- (2015) Daniela Ernst et al. NEUROMOLECULAR MEDICINE
- The Variant p.(Arg183Trp) in SPTLC2 Causes Late-Onset Hereditary Sensory Neuropathy
- (2015) Saranya Suriyanarayanan et al. NEUROMOLECULAR MEDICINE
- Sphingosine kinase 2 and sphingosine-1-phosphate promotes mitochondrial function in dopaminergic neurons of mouse model of Parkinson’s disease and in MPP+-treated MN9D cells in vitro
- (2015) M. Sivasubramanian et al. NEUROSCIENCE
- Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and AβAccumulation
- (2015) Maja Jazvinšćak Jembrek et al. Oxidative Medicine and Cellular Longevity
- Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis
- (2015) James C. Dodge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties
- (2015) Mariana Figuera-Losada et al. PLoS One
- Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease.
- (2014) Stefan Porubsky et al. CELL AND TISSUE RESEARCH
- Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats
- (2014) Alaa Othman et al. DIABETES
- Deficiency of Sphingosine-1-phosphate Lyase Impairs Lysosomal Metabolism of the Amyloid Precursor Protein
- (2014) Ilker Karaca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fibrillar Amyloid- Peptides Activate Microglia via TLR2: Implications for Alzheimer's Disease
- (2014) M. Jana et al. JOURNAL OF IMMUNOLOGY
- Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells
- (2014) S.-B. Jeon et al. JOURNAL OF IMMUNOLOGY
- Long term effects of enzyme replacement therapy in an Italian cohort of type 3 Gaucher patients
- (2014) Annalisa Sechi et al. MOLECULAR GENETICS AND METABOLISM
- Anti-Inflammatory Effects of α-Galactosylceramide Analogs in Activated Microglia: Involvement of the p38 MAPK Signaling Pathway
- (2014) Yeon-Hui Jeong et al. PLoS One
- PhotoImmunoNanoTherapy Reveals an Anticancer Role for Sphingosine Kinase 2 and Dihydrosphingosine-1-Phosphate
- (2013) Brian M. Barth et al. ACS Nano
- The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock
- (2013) Jérôme Lugrin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Systemic ceramide accumulation leads to severe and varied pathological consequences
- (2013) Abdulfatah M. Alayoubi et al. EMBO Molecular Medicine
- Glycosphingolipids: synthesis and functions
- (2013) Giovanni D'Angelo et al. FEBS Journal
- Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells
- (2013) Satoshi Uemura et al. GLYCOCONJUGATE JOURNAL
- Neuronal accumulation of glucosylceramide in a mouse model of neuronopathic Gaucher disease leads to neurodegeneration
- (2013) T. Farfel-Becker et al. HUMAN MOLECULAR GENETICS
- Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis
- (2013) F. G. Tafesse et al. JOURNAL OF CELL SCIENCE
- Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1
- (2013) Stephanie M. Cologna et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Specific changes of sulfatide levels in individuals with pre-clinical Alzheimer's disease: an early event in disease pathogenesis
- (2013) Hua Cheng et al. JOURNAL OF NEUROCHEMISTRY
- A lipid storage-like disorder contributes to cognitive decline in HIV-infected subjects
- (2013) V. V. R. Bandaru et al. NEUROLOGY
- Long term enzyme replacement therapy for Fabry disease: effectiveness on kidney, heart and brain
- (2013) Saskia M Rombach et al. Orphanet Journal of Rare Diseases
- Beyond the cherry-red spot: Ocular manifestations of sphingolipid-mediated neurodegenerative and inflammatory disorders
- (2013) Hui Chen et al. SURVEY OF OPHTHALMOLOGY
- Ceramide-Based Therapeutics for the Treatment of Cancer
- (2012) Brian M. Barth et al. Anti-Cancer Agents in Medicinal Chemistry
- Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease
- (2012) Einat B. Vitner et al. BRAIN
- Ceramide kinase deficiency improves diet-induced obesity and insulin resistance
- (2012) Susumu Mitsutake et al. FEBS LETTERS
- NADPH Oxidase 1 Mediates -Synucleinopathy in Parkinson's Disease
- (2012) A. C. Cristovao et al. JOURNAL OF NEUROSCIENCE
- A Nonpolar Blueberry Fraction Blunts NADPH Oxidase Activation in Neuronal Cells Exposed to Tumor Necrosis Factor-α
- (2012) Sally J. Gustafson et al. Oxidative Medicine and Cellular Longevity
- Lipid Raft Redox Signaling: Molecular Mechanisms in Health and Disease
- (2011) Si Jin et al. ANTIOXIDANTS & REDOX SIGNALING
- Globotriaosylceramide is correlated with oxidative stress and inflammation in Fabry patients treated with enzyme replacement therapy
- (2011) Giovana B. Biancini et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance
- (2011) Brian M. Barth et al. CANCER BIOLOGY & THERAPY
- Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells
- (2011) Brian M. Barth et al. CELLULAR SIGNALLING
- Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting Enzyme
- (2011) Nadia F. Lamour et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation
- (2011) Sang-Ho Choi et al. JOURNAL OF NEUROCHEMISTRY
- BACE1 Activity Is Modulated by Cell-Associated Sphingosine-1-Phosphate
- (2011) N. Takasugi et al. JOURNAL OF NEUROSCIENCE
- Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α
- (2011) Brian M. Barth et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Sphingosine-1-phosphate signaling and its role in disease
- (2011) Michael Maceyka et al. TRENDS IN CELL BIOLOGY
- Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions
- (2010) Ruben Van Doorn et al. GLIA
- Identification and characterization of 15 novel GALC gene mutations causing Krabbe disease
- (2010) Barbara Tappino et al. HUMAN MUTATION
- Fabry Disease Exhibiting Recurrent Stroke and Persistent Inflammation
- (2010) Yoko Kikumoto et al. INTERNAL MEDICINE
- Hereditary Sensory Neuropathy Type 1 Is Caused by the Accumulation of Two Neurotoxic Sphingolipids
- (2010) Anke Penno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate
- (2010) Deanna L. Siow et al. JOURNAL OF LIPID RESEARCH
- Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms
- (2010) Eric Norman et al. JOURNAL OF NEUROCHEMISTRY
- Impaired Ganglioside Metabolism in Huntington's Disease and Neuroprotective Role of GM1
- (2010) V. Maglione et al. JOURNAL OF NEUROSCIENCE
- Sphingolipids in Multiple Sclerosis
- (2010) Arundhati Jana et al. NEUROMOLECULAR MEDICINE
- Intrathecal increase of sphingosine 1-phosphate at early stage multiple sclerosis
- (2010) Alina Kułakowska et al. NEUROSCIENCE LETTERS
- Fabry disease
- (2010) Dominique P Germain Orphanet Journal of Rare Diseases
- Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration
- (2010) Christoph Kleinschnitz et al. PLOS BIOLOGY
- Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases
- (2009) Thomas L. Leto et al. ANTIOXIDANTS & REDOX SIGNALING
- Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
- (2009) Juliane Neumann et al. BRAIN
- Increased levels of inflammatory chemokines in amyotrophic lateral sclerosis
- (2009) J. Kuhle et al. EUROPEAN JOURNAL OF NEUROLOGY
- Subcellular Origin of Sphingosine 1-Phosphate Is Essential for Its Toxic Effect in Lyase-deficient Neurons
- (2009) Nadine Hagen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER
- (2009) Ana M. Vacaru et al. JOURNAL OF CELL BIOLOGY
- FTY720 Reduces Inflammation and Promotes Functional Recovery after Spinal Cord Injury
- (2009) Kangmin D. Lee et al. JOURNAL OF NEUROTRAUMA
- Proinflammatory cytokines provoke oxidative damage to actin in neuronal cells mediated by Rac1 and NADPH oxidase
- (2009) Brian M. Barth et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1
- (2009) David Smith et al. NEUROBIOLOGY OF DISEASE
- Oligodendrocyte Development and Myelin Biogenesis: Parsing Out the Roles of Glycosphingolipids
- (2009) Nicole Jackman et al. PHYSIOLOGY
- Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
- (2009) N. C. Hait et al. SCIENCE
- Randomized, controlled trial of miglustat in Gaucher's disease type 3
- (2008) Raphael Schiffmann et al. ANNALS OF NEUROLOGY
- Huntington's disease: from pathology and genetics to potential therapies
- (2008) Sara Imarisio et al. BIOCHEMICAL JOURNAL
- Sphingomyelin synthases regulate production of diacylglycerol at the Golgi
- (2008) Maristella Villani et al. BIOCHEMICAL JOURNAL
- The sphingolipid salvage pathway in ceramide metabolism and signaling
- (2008) Kazuyuki Kitatani et al. CELLULAR SIGNALLING
- Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann–Pick A disease
- (2008) James C. Dodge et al. EXPERIMENTAL NEUROLOGY
- Decreased activities of lysosomal acid alpha-D-galactosidase A in the leukocytes of sporadic Parkinson's disease
- (2008) Guanghua Wu et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
- (2008) Emyr Lloyd-Evans et al. NATURE MEDICINE
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now