SMPDL3b modulates insulin receptor signaling in diabetic kidney disease

Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes

(2017) Anis Ahmad et al.   FASEB JOURNAL

Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications

(2017) Andreas R. Janecke et al.   HUMAN MUTATION

Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome

(2017) Rathi Prasad et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency

(2017) Svjetlana Lovric et al.   JOURNAL OF CLINICAL INVESTIGATION

Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells

(2016) Io-Guané Rivera et al.   BIOCHEMICAL PHARMACOLOGY

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

(2016) Bhagirath Chaurasia et al.   Cell Metabolism

Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity

(2016) Alexei Gorelik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-κB Activation in Neutrophils

(2016) Kristin Baudiß et al.   JOURNAL OF IMMUNOLOGY

Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN- γ

(2016) Amandeep Bajwa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingolipids and phospholipids in insulin resistance and related metabolic disorders

(2016) Peter J. Meikle et al.   Nature Reviews Endocrinology

A conserved family of proteins facilitates nascent lipid droplet budding from the ER

(2015) Vineet Choudhary et al.   JOURNAL OF CELL BIOLOGY

Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling

(2015) Taroh Kinoshita et al.   JOURNAL OF LIPID RESEARCH

Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor

(2015) R. Villarreal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingosine kinase 2 and sphingosine-1-phosphate promotes mitochondrial function in dopaminergic neurons of mouse model of Parkinson’s disease and in MPP+-treated MN9D cells in vitro

(2015) M. Sivasubramanian et al.   NEUROSCIENCE

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

(2015) Leonhard X. Heinz et al.   Cell Reports

Partial inhibition of Cdk1 in G2phase overrides the SAC and decouples mitotic events

(2014) Rachael A McCloy et al.   CELL CYCLE

Autocrine/paracrine sphingosine-1-phosphate fuels proliferative and stemness qualities of glioblastoma stem cells

(2014) Giovanni Marfia et al.   GLIA

Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice

(2014) C. Graf et al.   JOURNAL OF IMMUNOLOGY

Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease

(2014) T.-H. Yoo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingosine-1–Phosphate, FTY720, and Sphingosine-1–Phosphate Receptors in the Pathobiology of Acute Lung Injury

(2013) Viswanathan Natarajan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Podocyte-Specific GLUT4-Deficient Mice Have Fewer and Larger Podocytes and Are Protected From Diabetic Nephropathy

(2013) J. Guzman et al.   DIABETES

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: On the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2

(2011) Kathrine Eduardsen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity

(2011) Akira Mima et al.   KIDNEY INTERNATIONAL

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

(2011) C H Kim et al.   LEUKEMIA

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

(2011) Changli Wei et al.   NATURE MEDICINE

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

(2011) A. Fornoni et al.   Science Translational Medicine

Sphingolipids and insulin resistance: the five Ws

(2010) Scott A Summers   CURRENT OPINION IN LIPIDOLOGY

Caveolin gene transfer improves glucose metabolism in diabetic mice

(2009) Koji Otsu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Ceramide 1-phosphate (C1P) promotes cell migration

(2008) María H. Granado et al.   CELLULAR SIGNALLING

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death

(2008) T. Tejada et al.   KIDNEY INTERNATIONAL

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Deregulation of sphingolipid metabolism in Alzheimer's disease

(2008) Xingxuan He et al.   NEUROBIOLOGY OF AGING

Ceramide 1-phosphate stimulates macrophage proliferation through activation of the PI3-kinase/PKB, JNK and ERK1/2 pathways

(2007) Patricia Gangoiti et al.   CELLULAR SIGNALLING