Understanding Dietary Intervention-Mediated Epigenetic Modifications in Metabolic Diseases
出版年份 2020 全文链接
标题
Understanding Dietary Intervention-Mediated Epigenetic Modifications in Metabolic Diseases
作者
关键词
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出版物
Frontiers in Genetics
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-10-15
DOI
10.3389/fgene.2020.590369
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
- (2020) Sangwon Byun et al. Nature Communications
- Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis
- (2020) Jose A. Viscarra et al. Nature Communications
- Long-term metabolic consequences of acute dioxin exposure differ between male and female mice
- (2020) Myriam P. Hoyeck et al. Scientific Reports
- A Positive Feedback Loop of TET3 and TGF-β1 Promotes Liver Fibrosis
- (2020) Yetao Xu et al. Cell Reports
- The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes
- (2020) Manvi Sharma et al. Frontiers in Genetics
- Glucocorticoid Metabolism in Obesity and Following Weight Loss
- (2020) Elina Akalestou et al. Frontiers in Endocrinology
- Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells
- (2020) Qi Yan Ang et al. CELL
- Adipose tissue mRNA expression of HDAC1, HDAC3 and HDAC9 in obese women in relation to obesity indices and insulin resistance
- (2020) Naghmeh Jannat Ali Pour et al. MOLECULAR BIOLOGY REPORTS
- Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
- (2020) Panu K. Luukkonen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
- (2020) Nicholas K. Vinckier et al. Nature Communications
- Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction
- (2020) Xiaojing Wei et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter
- (2020) Jingjie Wang et al. Nutrition & Metabolism
- Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
- (2019) Priya Rangan et al. Cell Reports
- Intermittent fasting beneficial effects on the steatosis and inflammation of the liver in mice fed a high-fat or a high-fructose diet
- (2019) Thatiany de Souza Marinho et al. NUTRITION
- Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
- (2019) Kenichiro Furuyama et al. NATURE
- Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Gene Expression at Promoter Regions in Euchromatin in Mice
- (2019) Jessica Mae Grindheim et al. GASTROENTEROLOGY
- Beneficial effects of SGLT2 inhibitors on fatty liver in type 2 diabetes: A common comorbidity associated with severe complications
- (2019) A.J. Scheen DIABETES & METABOLISM
- Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications
- (2019) Michele Longo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Impact of Caloric Restriction on the Epigenetic Signatures of Aging
- (2019) Noémie Gensous et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic Mechanisms in Hepatic Stellate Cell Activation During Liver Fibrosis and Carcinogenesis
- (2019) Marina Barcena-Varela et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Early Time-Restricted Feeding Improves 24-Hour Glucose Levels and Affects Markers of the Circadian Clock, Aging, and Autophagy in Humans
- (2019) Humaira Jamshed et al. Nutrients
- Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake
- (2019) Kevin D. Hall et al. Cell Metabolism
- Early Time‐Restricted Feeding Reduces Appetite and Increases Fat Oxidation But Does Not Affect Energy Expenditure in Humans
- (2019) Eric Ravussin et al. Obesity
- Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR
- (2019) Daniel Castellano-Castillo et al. PLoS One
- Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
- (2019) Jesús E. Villanueva et al. Nature Communications
- The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study
- (2019) Stephen D. Anton et al. Nutrients
- Carbohydrate Sensing Through the Transcription Factor ChREBP
- (2019) Paula Ortega-Prieto et al. Frontiers in Genetics
- Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
- (2019) Chia-Wei Cheng et al. CELL
- Histone methyltransferase G9a protects against acute liver injury through GSTP1
- (2019) Yu Zhang et al. CELL DEATH AND DIFFERENTIATION
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans
- (2019) Slaven Stekovic et al. Cell Metabolism
- Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity
- (2019) Sebastio Perrini et al. INTERNATIONAL JOURNAL OF OBESITY
- SIRT1 Activation Promotes β-Cell Regeneration by Activating Endocrine Progenitor Cells via AMPK Signaling-Mediated Fatty Acid Oxidation
- (2019) Shang Ying Wu et al. STEM CELLS
- Mechanisms and Evidence for Heart Failure Benefits from SGLT2 Inhibitors
- (2019) Cezary Wojcik et al. Current Cardiology Reports
- Glucagon-like peptide 1 (GLP-1)
- (2019) T.D. Müller et al. Molecular Metabolism
- Sex differences in metabolic regulation and diabetes susceptibility
- (2019) Blandine Tramunt et al. DIABETOLOGIA
- Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions
- (2019) Junki Miyamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Short-Chain Fatty Acid Acetate in Body Weight Control and Insulin Sensitivity
- (2019) Hernández et al. Nutrients
- Effects of Periodic Fasting on Fatty Liver Index—A Prospective Observational Study
- (2019) Stefan Drinda et al. Nutrients
- A Randomised Controlled Trial on the Effectiveness and Adherence of Modified Alternate-day Calorie Restriction in Improving Activity of Non-Alcoholic Fatty Liver Disease
- (2019) Muhammad Izzad Johari et al. Scientific Reports
- Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
- (2019) Ri Youn Kim et al. Jove-Journal of Visualized Experiments
- Ten-Hour Time-Restricted Eating Reduces Weight, Blood Pressure, and Atherogenic Lipids in Patients with Metabolic Syndrome
- (2019) Michael J. Wilkinson et al. Cell Metabolism
- Effects of Intermittent Fasting on Health, Aging, and Disease
- (2019) Rafael de Cabo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Histone deacetylase inhibition ameliorates hypertension and hyperglycemia in a model of Cushing’s syndrome
- (2018) Hae-Ahm Lee et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- GSK126 alleviates the obesity phenotype by promoting the differentiation of thermogenic beige adipocytes in diet-induced obese mice
- (2018) Xiaohui Wu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1
- (2018) Weili Xue et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes
- (2018) Elizabeth F. Sutton et al. Cell Metabolism
- Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota
- (2018) Francesca Cignarella et al. Cell Metabolism
- Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver
- (2018) Sara Della Torre et al. Cell Metabolism
- Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging
- (2018) Leanne M. Redman et al. Cell Metabolism
- Impaired endocrine-metabolic homeostasis: underlying mechanism of its induction by unbalanced diet
- (2018) Bárbara Maiztegui et al. CLINICAL SCIENCE
- Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension
- (2018) James H. Catterson et al. CURRENT BIOLOGY
- The Global Epidemic of the Metabolic Syndrome
- (2018) Mohammad G. Saklayen CURRENT HYPERTENSION REPORTS
- Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice
- (2018) Eleni Beli et al. DIABETES
- Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
- (2018) Amar Abderrahmani et al. DIABETES
- Intra- and inter-subject variability for increases in serum ketone bodies in patients with type 2 diabetes treated with the sodium glucose co-transporter 2 inhibitor canagliflozin
- (2018) David Polidori et al. DIABETES OBESITY & METABOLISM
- S6K1 controls epigenetic plasticity for the expression of pancreatic α/β cell marker genes
- (2018) Sang Ah Yi et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation
- (2018) Sunmi Seok et al. JOURNAL OF CLINICAL INVESTIGATION
- The effects of high glucose exposure on global gene expression and DNA methylation in human pancreatic islets
- (2018) Elin Hall et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- Food restriction promotes damage reduction in rat models of type 2 diabetes mellitus
- (2018) Carlos Vinicius Dalto da Rosa et al. PLoS One
- Liver-specific knockout of histone methyltransferase G9a impairs liver maturation and dysregulates inflammatory, cytoprotective, and drug-processing genes
- (2018) Hong Lu et al. XENOBIOTICA
- The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
- (2018) Julien Bricambert et al. Nature Communications
- Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function
- (2018) Lenan Zhuang et al. Nature Communications
- Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch
- (2018) Yohei Abe et al. Nature Communications
- Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways
- (2018) Glenn S. Gerhard et al. Clinical Epigenetics
- Wnt/β-Catenin Signaling and Obesity
- (2018) Na Chen et al. Frontiers in Physiology
- MC1568 improves insulin secretion in islets from type 2 diabetes patients and rescues β-cell dysfunction caused by Hdac7 upregulation
- (2018) Mahboubeh Daneshpajooh et al. ACTA DIABETOLOGICA
- Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements
- (2018) Salvatore Fabbiano et al. Cell Metabolism
- Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories
- (2018) Sarah J. Mitchell et al. Cell Metabolism
- Epigenetics and Epigenomics: Implications for Diabetes and Obesity
- (2018) Evan D. Rosen et al. DIABETES
- Increases in circulating levels of ketone bodies and cardiovascular protection with SGLT2 inhibitors: Is low-grade inflammation the neglected component?
- (2018) Francesco Prattichizzo et al. DIABETES OBESITY & METABOLISM
- TET2 facilitates PPARγ agonist–mediated gene regulation and insulin sensitization in adipocytes
- (2018) Fuyun Bian et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Time-restricted feeding causes irreversible metabolic disorders and gut microbiota shift in pediatric mice
- (2018) Dandan Hu et al. PEDIATRIC RESEARCH
- Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes
- (2018) Anubama Rajan et al. Scientific Reports
- Glucose tolerance and insulin sensitivity define adipocyte transcriptional programs in human obesity
- (2018) R. Gerlini et al. Molecular Metabolism
- Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis
- (2018) Patrycja Puchalska et al. Cell Metabolism
- Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats
- (2018) Hyun Cho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A time to fast
- (2018) Andrea Di Francesco et al. SCIENCE
- Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model
- (2018) Min-Yu Chung et al. Molecular Metabolism
- Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
- (2017) Vanessa D. de Mello et al. Epigenetics
- Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis
- (2017) Parambir S. Dulai et al. HEPATOLOGY
- Identification of the genomic region under epigenetic regulation during non-alcoholic fatty liver disease progression
- (2017) Kikuko Hotta et al. HEPATOLOGY RESEARCH
- Conical Modification of Forearm Free Flaps for Single-Stage Reconstruction After Total Orbital Exenteration
- (2017) Chad A. Purnell et al. JOURNAL OF CRANIOFACIAL SURGERY
- Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression
- (2017) Teresa Ramirez et al. JOURNAL OF HEPATOLOGY
- The Landscape of Histone Modifications in a High-Fat Diet-Induced Obese (DIO) Mouse Model
- (2017) Litong Nie et al. MOLECULAR & CELLULAR PROTEOMICS
- Intermittent calorie restriction largely counteracts the adverse health effects of a moderate-fat diet in aging C57BL/6J mice
- (2017) Fenni Rusli et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
- (2017) Stephen D. Anton et al. Obesity
- Targeting nuclear receptors for the treatment of fatty liver disease
- (2017) Naoki Tanaka et al. PHARMACOLOGY & THERAPEUTICS
- Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier
- (2017) Da Zhou et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Caloric restriction improves health and survival of rhesus monkeys
- (2017) Julie A. Mattison et al. Nature Communications
- Caloric restriction delays age-related methylation drift
- (2017) Shinji Maegawa et al. Nature Communications
- Nutrients and the Pancreas: An Epigenetic Perspective
- (2017) Andee Weisbeck et al. Nutrients
- Impact of Dietary Interventions on Noncoding RNA Networks and mRNAs Encoding Chromatin-Related Factors
- (2017) Christopher D. Green et al. Cell Reports
- SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion
- (2017) Qiang Chen et al. Cell Reports
- 36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent manner
- (2017) Line Hjort et al. Clinical Epigenetics
- Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individuals
- (2017) Donia Macartney-Coxson et al. Clinical Epigenetics
- Dnmt3a is an epigenetic mediator of adipose insulin resistance
- (2017) Dongjoo You et al. eLife
- E2F1, a Novel Regulator of Metabolism
- (2017) Pierre-Damien Denechaud et al. Frontiers in Endocrinology
- Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression
- (2017) Si Brask Sonne et al. Adipocyte
- Histone H3K9 Demethylase JMJD2B Activates Adipogenesis by Regulating H3K9 Methylation on PPARγ and C/EBPα during Adipogenesis
- (2017) Min-Kyung Jang et al. PLoS One
- Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats
- (2017) Shibin Ding et al. PLoS One
- Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity
- (2017) Gregory A. Raciti et al. Scientific Reports
- mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction
- (2016) Masaki Igarashi et al. CELL
- Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan
- (2016) Valter D. Longo et al. Cell Metabolism
- Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk
- (2016) Jennifer H. Stern et al. Cell Metabolism
- Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues
- (2016) Vanessa Pellegrinelli et al. DIABETOLOGIA
- HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
- (2016) Mahboubeh Daneshpajooh et al. DIABETOLOGIA
- Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
- (2016) Alexandra Kautzky-Willer et al. ENDOCRINE REVIEWS
- FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice
- (2016) Ting Zhang et al. ENDOCRINOLOGY
- Intermittent Fasting Promotes Fat Loss With Lean Mass Retention, Increased Hypothalamic Norepinephrine Content, and Increased Neuropeptide Y Gene Expression in Diet-Induced Obese Male Mice
- (2016) Juliet D. Gotthardt et al. ENDOCRINOLOGY
- Calorie restriction in overweight older adults: Do benefits exceed potential risks?
- (2016) Julie L. Locher et al. EXPERIMENTAL GERONTOLOGY
- Circadian Clock Control of Liver Metabolic Functions
- (2016) Hans Reinke et al. GASTROENTEROLOGY
- Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation
- (2016) Xing Zeng et al. GENES & DEVELOPMENT
- Is liver stiffness equal to liver fibrosis?
- (2016) Maja Thiele et al. HEPATOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet
- (2016) L Parrillo et al. INTERNATIONAL JOURNAL OF OBESITY
- Attenuation of diet-induced obesity and induction of white fat browning with a chemical inhibitor of histone deacetylases
- (2016) A Ferrari et al. INTERNATIONAL JOURNAL OF OBESITY
- Histone Deacetylase 1 (HDAC1) Negatively Regulates Thermogenic Program in Brown Adipocytes via Coordinated Regulation of Histone H3 Lysine 27 (H3K27) Deacetylation and Methylation
- (2016) Fenfen Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenomic and transcriptional control of insulin resistance
- (2016) E. D. Rosen JOURNAL OF INTERNAL MEDICINE
- Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice
- (2016) Zhenjiang Liu et al. JOURNAL OF LIPID RESEARCH
- S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis
- (2016) Sang Ah Yi et al. MOLECULAR CELL
- Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation
- (2016) Zhongyu Xie et al. MOLECULAR CELL
- Metabolic regulation of gene expression through histone acylations
- (2016) Benjamin R. Sabari et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Diet-induced obesity and insulin resistance are associated with brown fat degeneration in SIRT1-deficient mice
- (2016) Fen Xu et al. Obesity
- Adipose tissue fibrosis, hypertrophy, and hyperplasia: Correlations with diabetes in human obesity
- (2016) Lindsey A. Muir et al. Obesity
- Restricting feeding to the active phase in middle-aged mice attenuates adverse metabolic effects of a high-fat diet
- (2016) M.J. Duncan et al. PHYSIOLOGY & BEHAVIOR
- Gender Differences in Response to Prolonged Every-Other-Day Feeding on the Proliferation and Apoptosis of Hepatocytes in Mice
- (2016) Katarzyna Piotrowska et al. Nutrients
- Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2
- (2016) Dae-Hwan Kim et al. Cell Reports
- LSD1 Interacts with Zfp516 to Promote UCP1 Transcription and Brown Fat Program
- (2016) Audrey Sambeat et al. Cell Reports
- Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue
- (2016) Delphine Duteil et al. Cell Reports
- SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting
- (2016) Marie Boutant et al. Cell Reports
- A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations
- (2016) Han Zhang et al. PLoS Genetics
- Reversibility ofβ-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
- (2016) Chunjun Sheng et al. Journal of Diabetes Research
- Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
- (2016) Julien Bricambert et al. Molecular Metabolism
- Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients
- (2016) Henriette Kirchner et al. Molecular Metabolism
- Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders
- (2016) Sung Sik Choe et al. Frontiers in Endocrinology
- Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction
- (2016) Chikara Komiya et al. PLoS One
- Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1
- (2015) Yulia Haim et al. Autophagy
- Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
- (2015) Christian Baumeier et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Histone Deacetylase HDAC8 Promotes Insulin Resistance and -Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
- (2015) Y. Tian et al. CANCER RESEARCH
- Promoting Health and Longevity through Diet: From Model Organisms to Humans
- (2015) Luigi Fontana et al. CELL
- Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes
- (2015) Michael L. Multhaup et al. Cell Metabolism
- Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
- (2015) Aaron M. Cypess et al. Cell Metabolism
- Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity
- (2015) Dongning Pan et al. DEVELOPMENTAL CELL
- Medium-chain triglyceride ameliorates insulin resistance and inflammation in high fat diet-induced obese mice
- (2015) Shanshan Geng et al. EUROPEAN JOURNAL OF NUTRITION
- Gender-specific postnatal demethylation and establishment of epigenetic memory
- (2015) Yitzhak Reizel et al. GENES & DEVELOPMENT
- Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets
- (2015) Thierry Brun et al. HUMAN MOLECULAR GENETICS
- The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
- (2015) I Dahlman et al. INTERNATIONAL JOURNAL OF OBESITY
- MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics
- (2015) J A Deiuliis INTERNATIONAL JOURNAL OF OBESITY
- The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation
- (2015) Lin Zha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels
- (2015) Emma Nilsson et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- NAFLD: A multisystem disease
- (2015) Christopher D. Byrne et al. JOURNAL OF HEPATOLOGY
- Six and 12 Weeks of Caloric Restriction Increases β Cell Function and Lowers Fasting and Postprandial Glucose Concentrations in People with Type 2 Diabetes
- (2015) Matheni Sathananthan et al. JOURNAL OF NUTRITION
- Dietary restriction preserves the mass and function of pancreatic β cells via cell kinetic regulation and suppression of oxidative/ER stress in diabetic mice
- (2015) Yukiko Kanda et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans
- (2015) Ville T. Männistö et al. LIVER INTERNATIONAL
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia
- (2015) Andreia V. Pinho et al. PLoS One
- Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
- (2015) Pedro Gomes et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Liver fibrosis in non-alcoholic fatty liver disease - diagnostic challenge with prognostic significance
- (2015) Per Stål WORLD JOURNAL OF GASTROENTEROLOGY
- Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment
- (2015) Matteo Piciucchi et al. International Journal of Endocrinology
- JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis
- (2015) Yohei Abe et al. Nature Communications
- Differential DNA methylation of genes involved in fibrosis progression in non-alcoholic fatty liver disease and alcoholic liver disease
- (2015) Müjdat Zeybel et al. Clinical Epigenetics
- An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss
- (2015) Miles C Benton et al. GENOME BIOLOGY
- SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function
- (2015) Marie Boutant et al. Molecular Metabolism
- Circulating IGFBP-2 levels are incrementally linked to correlates of the metabolic syndrome and independently associated with VLDL triglycerides
- (2014) Sophie Carter et al. ATHEROSCLEROSIS
- Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets
- (2014) Elin Hall et al. BMC Medicine
- Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis
- (2014) Christoph A. Thaiss et al. CELL
- Time-Restricted Feeding Is a Preventative and Therapeutic Intervention against Diverse Nutritional Challenges
- (2014) Amandine Chaix et al. Cell Metabolism
- Fasting: Molecular Mechanisms and Clinical Applications
- (2014) Valter D. Longo et al. Cell Metabolism
- Adaptive Thermogenesis in White Adipose Tissue: Is Lactate the New Brown(ing)?
- (2014) L. Vergnes et al. DIABETES
- Browning of White Adipose Cells by Intermediate Metabolites: An Adaptive Mechanism to Alleviate Redox Pressure
- (2014) A. Carriere et al. DIABETES
- Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity
- (2014) Laia Bosch-Presegué et al. FEBS Journal
- Vascular rarefaction mediates whitening of brown fat in obesity
- (2014) Ippei Shimizu et al. JOURNAL OF CLINICAL INVESTIGATION
- Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia
- (2014) David G. Cotter et al. JOURNAL OF CLINICAL INVESTIGATION
- Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013
- (2014) Marie Ng et al. LANCET
- Suv39h1 Mediates AP-2 -Dependent Inhibition of C/EBP Expression during Adipogenesis
- (2014) Z.-C. Zhang et al. MOLECULAR AND CELLULAR BIOLOGY
- Gcn5 and PCAF Regulate PPAR and Prdm16 Expression To Facilitate Brown Adipogenesis
- (2014) Q. Jin et al. MOLECULAR AND CELLULAR BIOLOGY
- Calorie Restriction Decreases Murine and Human Pancreatic Tumor Cell Growth, Nuclear Factor-κB Activation, and Inflammation-Related Gene Expression in an Insulin-like Growth Factor-1−Dependent Manner
- (2014) Alison E. Harvey et al. PLoS One
- LSD1 promotes oxidative metabolism of white adipose tissue
- (2014) Delphine Duteil et al. Nature Communications
- Correction: Genome-Wide Associations between Genetic and Epigenetic Variation Influence mRNA Expression and Insulin Secretion in Human Pancreatic Islets
- (2014) PLoS Genetics
- Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion
- (2014) Tasnim Dayeh et al. PLoS Genetics
- Reducing Liver Fat by Low Carbohydrate Caloric Restriction Targets Hepatic Glucose Production in Non-Diabetic Obese Adults with Non-Alcoholic Fatty Liver Disease
- (2014) Haoyong Yu et al. Journal of Clinical Medicine
- Role of histone deacetylase 9 in regulating adipogenic differentiation and high fat diet-induced metabolic disease
- (2014) Tapan K Chatterjee et al. Adipocyte
- DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets
- (2013) Elin Hall et al. BMC Medical Genetics
- Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes
- (2013) Anna Biason-Lauber et al. Cell Metabolism
- DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
- (2013) Markus Ahrens et al. Cell Metabolism
- Glucagon-Induced Acetylation of Foxa2 Regulates Hepatic Lipid Metabolism
- (2013) Ferdinand von Meyenn et al. Cell Metabolism
- Anatomical Locations of Human Brown Adipose Tissue: Functional Relevance and Implications in Obesity and Type 2 Diabetes
- (2013) H. Sacks et al. DIABETES
- HDAC9 Knockout Mice Are Protected From Adipose Tissue Dysfunction and Systemic Metabolic Disease During High-Fat Feeding
- (2013) T. K. Chatterjee et al. DIABETES
- Very Low–Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and β-Cell Function in Type 2 Diabetic Patients
- (2013) Clifton Jackness et al. DIABETES
- Obesity Paradox Does Exist
- (2013) V. Hainer et al. DIABETES CARE
- Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets
- (2013) T. A. Dayeh et al. DIABETOLOGIA
- The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing
- (2013) L. Luu et al. DIABETOLOGIA
- Calorie restriction delays the progression of lesions to pancreatic cancer in the LSL-KrasG12D; Pdx-1/Cre mouse model of pancreatic cancer
- (2013) Susan Lanza-Jacoby et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Medium chain triglycerides dose-dependently prevent liver pathology in a rat model of non-alcoholic fatty liver disease
- (2013) Martin J J Ronis et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Deletion of SIRT1 From Hepatocytes in Mice Disrupts Lipin-1 Signaling and Aggravates Alcoholic Fatty Liver
- (2013) Huquan Yin et al. GASTROENTEROLOGY
- SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation
- (2013) Rui-Hong Wang et al. International Journal of Biological Sciences
- EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD
- (2013) Serena Vella et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenomic plasticity enables human pancreatic α to β cell reprogramming
- (2013) Nuria C. Bramswig et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
- (2013) Gijs den Besten et al. JOURNAL OF LIPID RESEARCH
- Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
- (2013) Steven E Kahn et al. LANCET
- SIRT1 interacts with metabolic transcriptional factors in the pancreas of insulin-resistant and calorie-restricted rats
- (2013) Yong-Ru Chen et al. MOLECULAR BIOLOGY REPORTS
- EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex
- (2013) Haruya Ohno et al. NATURE
- Brown and beige fat: development, function and therapeutic potential
- (2013) Matthew Harms et al. NATURE MEDICINE
- Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial
- (2013) Krista A Varady et al. Nutrition Journal
- Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults
- (2013) Ian J. Neeland et al. Obesity
- Butyrate-Producing Probiotics Reduce Nonalcoholic Fatty Liver Disease Progression in Rats: New Insight into the Probiotics for the Gut-Liver Axis
- (2013) Hitoshi Endo et al. PLoS One
- Dietary Restriction Depends on Nutrient Composition to Extend Chronological Lifespan in Budding Yeast Saccharomyces cerevisiae
- (2013) Ziyun Wu et al. PLoS One
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- A Fasting-Responsive Signaling Pathway that Extends Life Span in C. elegans
- (2013) Masaharu Uno et al. Cell Reports
- H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
- (2013) Ji-Eun Lee et al. eLife
- SIRT1 and energy metabolism
- (2012) X. Li ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Very-low-calorie diet: a quick therapeutic tool to improve β cell function in morbidly obese patients with type 2 diabetes
- (2012) Ilaria Malandrucco et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans
- (2012) Ksenia Sevastianova et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Adipogenesis: From Stem Cell to Adipocyte
- (2012) Qi Qun Tang et al. Annual Review of Biochemistry
- Dietary restriction increases site-specific histone H3 acetylation in rat liver: Possible modulation by sirtuins
- (2012) Kyojiro Kawakami et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
- (2012) Li Qiang et al. CELL
- Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet
- (2012) Megumi Hatori et al. Cell Metabolism
- A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
- (2012) Jalal Taneera et al. Cell Metabolism
- Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis
- (2012) Lifeng Wang et al. EMBO JOURNAL
- Dietary obesity-associated Hif1 activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
- (2012) J. Krishnan et al. GENES & DEVELOPMENT
- Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease
- (2012) Carlos Jose Pirola et al. GUT
- Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition
- (2012) Rui-Hong Wang et al. International Journal of Biological Sciences
- Thyroid hormone regulation of Sirtuin 1 expression and implications to integrated responses in fasted mice
- (2012) Aline Cordeiro et al. JOURNAL OF ENDOCRINOLOGY
- Alternate day fasting (ADF) with a high-fat diet produces similar weight loss and cardio-protection as ADF with a low-fat diet
- (2012) Monica C. Klempel et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Increased DNA Methylation and Decreased Expression ofPDX-1in Pancreatic Islets from Patients with Type 2 Diabetes
- (2012) Beatrice T. Yang et al. MOLECULAR ENDOCRINOLOGY
- Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
- (2012) T. Shimazu et al. SCIENCE
- Calorie Restriction from a Young Age Preserves the Functions of Pancreatic ^|^beta; Cells in Aging Rats
- (2012) Xiao-ye He et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure
- (2012) Shinjiro Hino et al. Nature Communications
- SIRT2 as a Therapeutic Target for Age-Related Disorders
- (2012) Rita Machado de Oliveira et al. Frontiers in Pharmacology
- Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction
- (2011) Jeffrey D Browning et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Sirtuin 1 in lipid metabolism and obesity
- (2011) Thaddeus T. Schug et al. ANNALS OF MEDICINE
- A Hormone-Dependent Module Regulating Energy Balance
- (2011) Biao Wang et al. CELL
- Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis
- (2011) Maria M. Mihaylova et al. CELL
- Control of pancreatic β-cell fate by insulin signaling: The sweet spot hypothesis
- (2011) James D Johnson et al. CELL CYCLE
- Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
- (2011) Shiro Maeda et al. Clinical and Experimental Nephrology
- Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans
- (2011) Changting Xiao et al. DIABETES
- SirT1 Regulates Adipose Tissue Inflammation
- (2011) M. P. Gillum et al. DIABETES
- EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
- (2011) E. Ezhkova et al. GENES & DEVELOPMENT
- DNA methylation profiles of human active and inactive X chromosomes
- (2011) A. J. Sharp et al. GENOME RESEARCH
- Dietary methyl-consuming compounds and metabolic syndrome
- (2011) Shi-Sheng Zhou et al. HYPERTENSION RESEARCH
- Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: An analysis of the PROactive study population
- (2011) Wolfram Doehner et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance
- (2011) Tie Fu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL
- (2011) Partha Chakrabarti et al. JOURNAL OF LIPID RESEARCH
- The effect of caloric restriction and glycemic load on measures of oxidative stress and antioxidants in humans: Results from the calerie trial of human caloric restriction
- (2011) Mohsen Meydani et al. Journal of Nutrition Health & Aging
- SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians
- (2011) Yan Dong et al. MOLECULAR GENETICS AND METABOLISM
- Fasting and High-Fat Diet Alter Histone Deacetylase Expression in the Medial Hypothalamus
- (2011) Hiromasa Funato et al. PLoS One
- A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism
- (2011) D. Feng et al. SCIENCE
- Epigenetic diet: impact on the epigenome and cancer
- (2011) Tabitha M Hardy et al. Epigenomics
- Haploinsufficiency of HDAC4 Causes Brachydactyly Mental Retardation Syndrome, with Brachydactyly Type E, Developmental Delays, and Behavioral Problems
- (2010) Stephen R. Williams et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in ratsThis paper is one of a selection of papers published in this special issue entitled “Second International Symposium on Recent Advances in Basic, Clinical, and Social Medicine” and has undergone the Journal's usual peer review process.
- (2010) Yong-Ru Chen et al. Biochemistry and Cell Biology
- SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
- (2010) Tadahiro Shimazu et al. Cell Metabolism
- Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets
- (2010) B. T. Yang et al. DIABETOLOGIA
- Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
- (2010) Qihuang Jin et al. EMBO JOURNAL
- Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/−Mice: A Role of Lipid Mobilization and Inflammation
- (2010) Fen Xu et al. ENDOCRINOLOGY
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
- (2010) A. K. Walker et al. GENES & DEVELOPMENT
- The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women
- (2010) M N Harvie et al. INTERNATIONAL JOURNAL OF OBESITY
- Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice
- (2010) Xinmei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Class II Histone Deacetylases Limit GLUT4 Gene Expression during Adipocyte Differentiation
- (2010) Juston Weems et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice
- (2010) Cuiying Xiao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
- (2010) Julien Bricambert et al. JOURNAL OF CLINICAL INVESTIGATION
- Fasting promotes the expression of SIRT1, an NAD+-dependent protein deacetylase, via activation of PPARα in mice
- (2010) Satoru Hayashida et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- A human gut microbial gene catalogue established by metagenomic sequencing
- (2010) Junjie Qin et al. NATURE
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
- (2010) Benjamin F Voight et al. NATURE GENETICS
- Genomics, Type 2 Diabetes, and Obesity
- (2010) Mark I. McCarthy NEW ENGLAND JOURNAL OF MEDICINE
- Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis
- (2010) L. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of caloric restriction on SIRT1 expression and apoptosis of islet beta cells in type 2 diabetic rats
- (2009) Xiangqun Deng et al. ACTA DIABETOLOGICA
- Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
- (2009) Kathryn Moynihan Ramsey et al. AGING CELL
- Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults
- (2009) Krista A Varady et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction
- (2009) Luigi Bouchard et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss
- (2009) Michael K. Badman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
- (2009) Takeshi Yoshizaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Histochemical demonstration of monocarboxylate transporters in mouse brown adipose tissue
- (2009) Toshihiko Iwanaga et al. BIOMEDICAL RESEARCH-TOKYO
- Histone Methylation Regulator PTIP Is Required for PPARγ and C/EBPα Expression and Adipogenesis
- (2009) Young-Wook Cho et al. Cell Metabolism
- Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
- (2009) Aparna Purushotham et al. Cell Metabolism
- Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
- (2009) Z. Gao et al. DIABETES
- Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
- (2009) Petra Louis et al. FEMS MICROBIOLOGY LETTERS
- MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis
- (2009) Jelena Mann et al. GASTROENTEROLOGY
- Polycomb protein Ezh2 regulates pancreatic -cell Ink4a/Arf expression and regeneration in diabetes mellitus
- (2009) H. Chen et al. GENES & DEVELOPMENT
- Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
- (2009) Takeshi Inagaki et al. GENES TO CELLS
- Protective effects of trichostatin A on liver injury in septic mice
- (2009) Li Zhang et al. HEPATOLOGY RESEARCH
- Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
- (2009) Luan Shu et al. HUMAN MOLECULAR GENETICS
- Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice
- (2009) Chenhong Zhang et al. ISME Journal
- Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet
- (2009) Igor P. Pogribny et al. JOURNAL OF HEPATOLOGY
- Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
- (2009) Keisuke Tateishi et al. NATURE
- SIRT1 and insulin resistance
- (2009) Fengxia Liang et al. Nature Reviews Endocrinology
- SIRT1 Transcription Is Decreased in Visceral Adipose Tissue of Morbidly Obese Patients with Severe Hepatic Steatosis
- (2009) Cíntia dos Santos Costa et al. OBESITY SURGERY
- Effect of a Standardised Dietary Restriction Protocol on Multiple Laboratory Strains of Drosophila melanogaster
- (2009) Richard C. Grandison et al. PLoS One
- SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats
- (2009) D. M. Erion et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
- (2009) R. J. Colman et al. SCIENCE
- Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
- (2009) Daniel I. Chasman et al. PLoS Genetics
- Association between insulin secretion, insulin sensitivity and type 2 diabetes susceptibility variants identified in genome-wide association studies
- (2008) Stephanie-May Ruchat et al. ACTA DIABETOLOGICA
- Adaptation to intermittent stress promotes maintenance of β-cell compensation: comparison with food restriction
- (2008) Holly E. Bates et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2008) Joanne M. Ajmo et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Selective versus Total Insulin Resistance: A Pathogenic Paradox
- (2008) Michael S. Brown et al. Cell Metabolism
- Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation
- (2008) Jérôme N. Feige et al. Cell Metabolism
- Overexpression of SIRT1 Protects Pancreatic -Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor- B Signaling Pathway
- (2008) J.-H. Lee et al. DIABETES
- -Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of -Cell Mass in Humans
- (2008) J. J. Meier et al. DIABETES
- Adipose Tissue: The New Endocrine Organ? A Review Article
- (2008) Susan E. Wozniak et al. DIGESTIVE DISEASES AND SCIENCES
- Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks
- (2008) Sarah K Knutson et al. EMBO JOURNAL
- Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A
- (2008) Florian Thieringer et al. GENE
- Tissue-specific regulation of SIRT1 by calorie restriction
- (2008) D. Chen et al. GENES & DEVELOPMENT
- GLUT4 Enhancer Factor (GEF) Interacts with MEF2A and HDAC5 to Regulate theGLUT4Promoter in Adipocytes
- (2008) David P. Sparling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes
- (2008) T. Yoshizaki et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ
- (2008) Fei Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans
- (2008) Sakiko Honjoh et al. NATURE
- A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
- (2008) Yi Liu et al. NATURE
- Effect of 6-Month Calorie Restriction and Exercise on Serum and Liver Lipids and Markers of Liver Function
- (2008) D. Enette Larson-Meyer et al. Obesity
- Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9
- (2008) Min Wei et al. PLoS Genetics
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
- (2008) Jamie L. Barger et al. PLoS One
- Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
- (2008) J. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sirt1 protects against high-fat diet-induced metabolic damage
- (2008) P. T. Pfluger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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