MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics
出版年份 2015 全文链接
标题
MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF OBESITY
Volume 40, Issue 1, Pages 88-101
出版商
Springer Nature
发表日期
2015-08-27
DOI
10.1038/ijo.2015.170
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes
- (2015) Michael L. Multhaup et al. Cell Metabolism
- Identification of Circulating miR-101, miR-375 and miR-802 as Biomarkers for Type 2 Diabetes
- (2015) Chigusa Higuchi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids
- (2015) Daniel F. Vatner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-155 Deficiency Results in Decreased Macrophage Inflammation and Attenuated Atherogenesis in Apolipoprotein E–Deficient Mice
- (2014) Fen Du et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells
- (2014) Fengyun Wen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring
- (2014) R. O. Benatti et al. BRITISH JOURNAL OF NUTRITION
- Adipose Tissue Macrophages Promote Myelopoiesis and Monocytosis in Obesity
- (2014) Prabhakara R. Nagareddy et al. Cell Metabolism
- Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets
- (2014) Vasumathi Kameswaran et al. Cell Metabolism
- miR33 Inhibition Overcomes Deleterious Effects of Diabetes Mellitus on Atherosclerosis Plaque Regression in Mice
- (2014) Emilie Distel et al. CIRCULATION RESEARCH
- A Novel Function of MicroRNA 130a-3p in Hepatic Insulin Sensitivity and Liver Steatosis
- (2014) F. Xiao et al. DIABETES
- Maternal Protein Restriction Leads to Pancreatic Failure in Offspring: Role of Misexpressed MicroRNA-375
- (2014) O. Dumortier et al. DIABETES
- MicroRNA-29 Fine-tunes the Expression of Key FOXA2-Activated Lipid Metabolism Genes and Is Dysregulated in Animal Models of Insulin Resistance and Diabetes
- (2014) C. L. Kurtz et al. DIABETES
- Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization
- (2014) Francisco J. Ortega et al. DIABETES CARE
- Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice
- (2014) L. Goedeke et al. EMBO Molecular Medicine
- Differential Expression of MicroRNAs in Omental Adipose Tissue From Gestational Diabetes Mellitus Subjects Reveals miR-222 as a Regulator of ERα Expression in Estrogen-Induced Insulin Resistance
- (2014) Zhonghua Shi et al. ENDOCRINOLOGY
- Expression Profiling of PPARγ-Regulated MicroRNAs in Human Subcutaneous and Visceral Adipogenesis in both Genders
- (2014) Jing Yu et al. ENDOCRINOLOGY
- Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease
- (2014) Duarte M. S. Ferreira et al. FEBS Journal
- Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
- (2014) Cynthia L. Ogden et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Microvesicle-Shuttled miR-130b Reduces Fat Deposition in Recipient Primary Cultured Porcine Adipocytes by Inhibiting PPAR-γ Expression
- (2014) Shifeng Pan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Plasma Exosome MicroRNA Profiling Unravels a New Potential Modulator of Adiponectin Pathway in Diabetes: Effect of Glycemic Control
- (2014) Donato Santovito et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Early-postnatal changes in adiposity and lipids profile by transgenerational developmental programming in swine with obesity/leptin resistance
- (2014) Antonio Gonzalez-Bulnes et al. JOURNAL OF ENDOCRINOLOGY
- KSRP and MicroRNA 145 Are Negative Regulators of Lipolysis in White Adipose Tissue
- (2014) Y.-Y. Lin et al. MOLECULAR AND CELLULAR BIOLOGY
- MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function
- (2014) T. Fu et al. MOLECULAR AND CELLULAR BIOLOGY
- The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment
- (2014) Delphine Crépin et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
- (2014) Pieter Mestdagh et al. NATURE METHODS
- MicroRNAs Regulate Human Adipocyte Lipolysis: Effects of miR-145 Are Linked to TNF-α
- (2014) Silvia Lorente-Cebrián et al. PLoS One
- Effects of Calorie Restriction and Diet-Induced Obesity on Murine Colon Carcinogenesis, Growth and Inflammatory Factors, and MicroRNA Expression
- (2014) Susan E. Olivo-Marston et al. PLoS One
- The Expression of LEP, LEPR, IGF1 and IL10 in Obesity and the Relationship with microRNAs
- (2014) Renata Viesti A. Collares et al. PLoS One
- MicroRNA-223 coordinates cholesterol homeostasis
- (2014) Kasey C. Vickers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- let-7 Enhances Osteogenesis and Bone Formation While Repressing Adipogenesis of Human Stromal/Mesenchymal Stem Cells by Regulating HMGA2
- (2014) Jianfeng Wei et al. STEM CELLS AND DEVELOPMENT
- Imperfect centered miRNA binding sites are common and can mediate repression of target mRNAs
- (2014) Hilary C Martin et al. GENOME BIOLOGY
- Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7
- (2013) Lake Q. Jiang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- MicroRNA profiling links miR-378 to enhanced adipocyte lipolysis in human cancer cachexia
- (2013) Agné Kulyté et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease
- (2013) Maarten Hulsmans et al. CARDIOVASCULAR RESEARCH
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell
- (2013) Sudhir G. Tattikota et al. Cell Metabolism
- Decreased MicroRNA-221 is Associated with High Levels of TNF-a in Human Adipose Tissue-Derived Mesenchymal Stem Cells From Obese Woman
- (2013) Wen-Wen Chou et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Targeting the Circulating MicroRNA Signature of Obesity
- (2013) F. J. Ortega et al. CLINICAL CHEMISTRY
- RNA-Binding Protein PTB and MicroRNA-221 Coregulate AdipoR1 Translation and Adiponectin Signaling
- (2013) Y. Lustig et al. DIABETES
- Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α
- (2013) A. Meerson et al. DIABETOLOGIA
- Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes
- (2013) Valeria Nesca et al. DIABETOLOGIA
- Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content
- (2013) Tod Fullston et al. FASEB JOURNAL
- Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring
- (2013) Lisa M. Nicholas et al. FASEB JOURNAL
- MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3β of Wnt/β-catenin signaling pathway
- (2013) Hu Chen et al. FEBS LETTERS
- TNFα-induced miR-130 resulted in adipocyte dysfunction during obesity-related inflammation
- (2013) Chongtae Kim et al. FEBS LETTERS
- Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women
- (2013) C Nardelli et al. INTERNATIONAL JOURNAL OF OBESITY
- miR-200s Contribute to Interleukin-6 (IL-6)-induced Insulin Resistance in Hepatocytes
- (2013) Lin Dou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Changes in Circulating MicroRNAs Are Associated With Childhood Obesity
- (2013) Anna Prats-Puig et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The Impact of Childhood Obesity on Inflammation, Innate Immune Cell Frequency, and Metabolic MicroRNA Expression
- (2013) Eirin Carolan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Early leptin blockade predisposes fat-fed rats to overweight and modifies hypothalamic microRNAs
- (2013) Charlotte Benoit et al. JOURNAL OF ENDOCRINOLOGY
- Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease
- (2013) Hisamitsu Miyaaki et al. LIVER INTERNATIONAL
- MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2
- (2013) Ying Zhang et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
- (2013) Jan-Wilhelm Kornfeld et al. NATURE
- Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes
- (2013) Jeanette Baran-Gale et al. PLoS One
- Serum Circulating microRNA Profiling for Identification of Potential Type 2 Diabetes and Obesity Biomarkers
- (2013) Nuria Pescador et al. PLoS One
- MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells
- (2013) Hyunjoo Lee et al. PLoS One
- MiRNA-181a Regulates Adipogenesis by Targeting Tumor Necrosis Factor-α (TNF-α) in the Porcine Model
- (2013) Hongyi Li et al. PLoS One
- Deep Sequencing of Small RNA Repertoires in Mice Reveals Metabolic Disorders-Associated Hepatic miRNAs
- (2013) Tingming Liang et al. PLoS One
- Urinary miR-29 Correlates with Albuminuria and Carotid Intima-Media Thickness in Type 2 Diabetes Patients
- (2013) Hui Peng et al. PLoS One
- Macrophage microvesicles induce macrophage differentiation and miR-223 transfer
- (2012) N. Ismail et al. BLOOD
- Reduction of dietary glycaemic load modifies the expression of microRNA potentially associated with energy balance and cancer pathways in pre-menopausal women
- (2012) Susan E. McCann et al. BRITISH JOURNAL OF NUTRITION
- MicroRNA-130b and microRNA-374b mediate the effect of maternal dietary protein on offspring lipid metabolism in Meishan pigs
- (2012) Shifeng Pan et al. BRITISH JOURNAL OF NUTRITION
- A Novel Regulator of Macrophage Activation
- (2012) Guoqing Zhuang et al. CIRCULATION
- Developing MicroRNA Therapeutics
- (2012) Eva van Rooij et al. CIRCULATION RESEARCH
- Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity
- (2012) E. Arner et al. DIABETES
- Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity
- (2012) B. Zhou et al. DIABETOLOGIA
- MiRNA-21 Reverses High Glucose and High Insulin Induced Insulin Resistance in 3T3-L1 Adipocytes through Targeting Phosphatase and Tensin Homologue
- (2012) H.-y. Ling et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1 Production
- (2012) M. Haneklaus et al. JOURNAL OF IMMUNOLOGY
- miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes
- (2012) N. H. Foley et al. JOURNAL OF LEUKOCYTE BIOLOGY
- MicroRNAs in metabolism and metabolic disorders
- (2012) Veerle Rottiers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin
- (2012) Maarten Hulsmans et al. PLoS One
- Differential Expression of MicroRNAs in Adipose Tissue after Long-Term High-Fat Diet-Induced Obesity in Mice
- (2012) Dionysios V. Chartoumpekis et al. PLoS One
- c-Jun Amino-Terminal Kinase-1 Mediates Glucose-Responsive Upregulation of the RNA Editing Enzyme ADAR2 in Pancreatic Beta-Cells
- (2012) Liu Yang et al. PLoS One
- miRandola: Extracellular Circulating MicroRNAs Database
- (2012) Francesco Russo et al. PLoS One
- miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells
- (2012) Hongling Li et al. Stem Cell Research
- A Resource for the Conditional Ablation of microRNAs in the Mouse
- (2012) Chong Yon Park et al. Cell Reports
- TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors
- (2011) Sanhong Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Do repeated arrays of regulatory small-RNA genes elicit genomic imprinting?
- (2011) Stéphane Labialle et al. BIOESSAYS
- The Lin28/let-7 Axis Regulates Glucose Metabolism
- (2011) Hao Zhu et al. CELL
- MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling
- (2011) Hong-Yan Ling et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells
- (2011) David F. Steiner et al. IMMUNITY
- miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes
- (2011) Harsh Dweep et al. JOURNAL OF BIOMEDICAL INFORMATICS
- Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers
- (2011) H. M. Heneghan et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
- (2011) Katey J. Rayner et al. JOURNAL OF CLINICAL INVESTIGATION
- Obesity is associated with hypothalamic injury in rodents and humans
- (2011) Joshua P. Thaler et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNAs 103 and 107 regulate insulin sensitivity
- (2011) Mirko Trajkovski et al. NATURE
- Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
- (2011) Katey J. Rayner et al. NATURE
- Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
- (2011) Sabine D. Jordan et al. NATURE CELL BIOLOGY
- MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
- (2011) Kasey C. Vickers et al. NATURE CELL BIOLOGY
- Silencing of microRNA families by seed-targeting tiny LNAs
- (2011) Susanna Obad et al. NATURE GENETICS
- Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
- (2011) J. D. Arroyo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs
- (2011) R. J. A. Frost et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study
- (2010) Lei Kong et al. ACTA DIABETOLOGICA
- Statistical Evaluation of a Biomarker
- (2010) Patrick Ray et al. ANESTHESIOLOGY
- Circulating MicroRNAs in Patients With Coronary Artery Disease
- (2010) Stephan Fichtlscherer et al. CIRCULATION RESEARCH
- Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes
- (2010) Anna Zampetaki et al. CIRCULATION RESEARCH
- The MicroRNA Spectrum in 12 Body Fluids
- (2010) J. A. Weber et al. CLINICAL CHEMISTRY
- Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes
- (2010) B. M. Herrera et al. DIABETOLOGIA
- MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism
- (2010) Dimitrios Iliopoulos et al. JOURNAL OF LIPID RESEARCH
- miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor Expression
- (2010) E. K. Lee et al. MOLECULAR AND CELLULAR BIOLOGY
- MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation
- (2010) Tao Li et al. NATURE IMMUNOLOGY
- MicroRNA control of signal transduction
- (2010) Masafumi Inui et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
- (2010) K. J. Rayner et al. SCIENCE
- ADAR editing in double-stranded UTRs and other noncoding RNA sequences
- (2010) Heather A. Hundley et al. TRENDS IN BIOCHEMICAL SCIENCES
- Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
- (2010) Iain J Gallagher et al. Genome Medicine
- Origins and Mechanisms of miRNAs and siRNAs
- (2009) Richard W. Carthew et al. CELL
- MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity
- (2009) H. Xie et al. DIABETES
- MicroRNAlet-7Regulates 3T3-L1 Adipogenesis
- (2009) Tingwan Sun et al. MOLECULAR ENDOCRINOLOGY
- Many roads to maturity: microRNA biogenesis pathways and their regulation
- (2009) Julia Winter et al. NATURE CELL BIOLOGY
- MicroRNA Expression in Human Omental and Subcutaneous Adipose Tissue
- (2009) Nora Klöting et al. PLoS One
- miR-375 maintains normal pancreatic - and -cell mass
- (2009) M. N. Poy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet
- (2008) Rieko Takanabe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
- (2008) R. D. Morin et al. GENOME RESEARCH
- Most mammalian mRNAs are conserved targets of microRNAs
- (2008) R. C. Friedman et al. GENOME RESEARCH
- Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes
- (2008) Manlio Vinciguerra et al. HEPATOLOGY
- LNA-mediated microRNA silencing in non-human primates
- (2008) Joacim Elmén et al. NATURE
- The microRNA miR-8 is a conserved negative regulator of Wnt signaling
- (2008) J. A. Kennell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circulating microRNAs as stable blood-based markers for cancer detection
- (2008) P. S. Mitchell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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