Airway Microbiota and the Implications of Dysbiosis in Asthma

Next-generation sequencing (NGS) in the microbiological world: How to make the most of your money

(2017) Antony T. Vincent et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Early-life respiratory infections and asthma development

(2016) Avraham Beigelman et al.   Current Opinion in Allergy and Clinical Immunology

Characterisation and therapeutic manipulation of the gut microbiome in inflammatory bowel disease

(2016) J. Schulberg et al.   INTERNAL MEDICINE JOURNAL

Deciphering bifidobacterial-mediated metabolic interactions and their impact on gut microbiota by a multi-omics approach

(2016) Francesca Turroni et al.   ISME Journal

Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways

(2016) Darcy R. Denner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Risk of Asthma from Cesarean Delivery Depends on Membrane Rupture

(2016) Astrid Sevelsted et al.   JOURNAL OF PEDIATRICS

Susceptibility to Lower Respiratory Infections in Childhood is Associated with Perturbation of the Cytokine Response to Pathogenic Airway Bacteria

(2016) Nadja Hawwa Vissing et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

(2016) Amy Langdon et al.   Genome Medicine

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

(2016) Leopoldo N. Segal et al.   Nature Microbiology

Early Respiratory Infections and the Development of Asthma in the First 27 Years of Life

(2015) Aino K. Rantala et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Homeostasis and its disruption in the lung microbiome

(2015) Robert P. Dickson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Recruited Alveolar Macrophages, in Response to Airway Epithelial–Derived Monocyte Chemoattractant Protein 1/CCL2, Regulate Airway Inflammation and Remodeling in Allergic Asthma

(2015) Yong Gyu Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Integrating microbial and host transcriptomics to characterize asthma-associated microbial communities

(2015) Eduardo Castro-Nallar et al.   BMC Medical Genomics

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Microbiota in Allergy and Asthma and the Emerging Relationship with the Gut Microbiome

(2015) Kei E. Fujimura et al.   Cell Host & Microbe

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

(2015) Fredrik Bäckhed et al.   Cell Host & Microbe

The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development

(2015) Shu Mei Teo et al.   Cell Host & Microbe

A comprehensive review of the nasal microbiome in chronic rhinosinusitis (CRS)

(2015) M. Mahdavinia et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Role of the Skin Microbiome in Atopic Dermatitis

(2015) Michael R. Williams et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Host-Microbiota Interactions in the Intestine

(2015) Charles O. Elson et al.   DIGESTIVE DISEASES

Retracted: Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance

(2015) Chris S Earl et al.   EMBO Molecular Medicine

The development of allergic inflammation in a murine house dust mite asthma model is suppressed by synbiotic mixtures of non-digestible oligosaccharides and Bifidobacterium breve M-16V

(2015) K. A. T. Verheijden et al.   EUROPEAN JOURNAL OF NUTRITION

Airway dysbiosis:Haemophilus influenzaeandTropherymain poorly controlled asthma

(2015) Jodie L. Simpson et al.   EUROPEAN RESPIRATORY JOURNAL

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

(2015) Monika Schaubeck et al.   GUT

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Microbiota and host immune responses: a love-hate relationship

(2015) Sarah Tomkovich et al.   IMMUNOLOGY

Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae

(2015) Mirjam Urb et al.   INFECTION AND IMMUNITY

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels

(2015) Michaela Schedel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The airway microbiome in patients with severe asthma: Associations with disease features and severity

(2015) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The microbiome in asthma

(2015) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma

(2015) Girolamo Pelaia et al.   MEDIATORS OF INFLAMMATION

Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma

(2015) Pinja Ilmarinen et al.   MEDIATORS OF INFLAMMATION

Multi -omics and metabolic modelling pipelines: Challenges and tools for systems microbiology

(2015) Marco Fondi et al.   MICROBIOLOGICAL RESEARCH

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

The microbiome of the urinary tract—a role beyond infection

(2015) Samantha A. Whiteside et al.   Nature Reviews Urology

Clostridium difficile Infection

(2015) Daniel A. Leffler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Nasopharyngeal Bacteria and Respiratory Viruses in Acute Symptoms of Young Children

(2015) Johanna M. Uitti et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma

(2015) Marcos Pérez-Losada et al.   PLoS One

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Early infancy microbial and metabolic alterations affect risk of childhood asthma

(2015) Marie-Claire Arrieta et al.   Science Translational Medicine

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

(2015) Arvind Venkataraman et al.   mBio

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

Epidemiology and economic burden of asthma

(2015) Patricia A. Loftus et al.   International Forum of Allergy & Rhinology

Early Exposure to Dogs and Farm Animals and the Risk of Childhood Asthma

(2015) Tove Fall et al.   JAMA Pediatrics

Individualized medicine and the microbiome in reproductive tract

(2015) Andrea G. Braundmeier et al.   Frontiers in Physiology

Age-of-asthma onset as a determinant of different asthma phenotypes in adults: a systematic review and meta-analysis of the literature

(2015) Daniel J Tan et al.   Expert Review of Respiratory Medicine

Is asthma prevalence still increasing?

(2015) Bo Lundbäck et al.   Expert Review of Respiratory Medicine

Bacterial Exposures and Associations with Atopy and Asthma in Children

(2015) Maria Valkonen et al.   PLoS One

Assessment and Selection of Competing Models for Zero-Inflated Microbiome Data

(2015) Lizhen Xu et al.   PLoS One

Early Respiratory Microbiota Composition Determines Bacterial Succession Patterns and Respiratory Health in Children

(2014) Giske Biesbroek et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

LPS Modulates Rhinovirus-Induced Chemokine Secretion in Monocytes and Macrophages

(2014) Maya R. Karta et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Indoor-Air Microbiome in an Urban Subway Network: Diversity and Dynamics

(2014) Marcus H. Y. Leung et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Moraxella catarrhalis-induced pro-inflammatory immune response is enhanced by the activation of the epidermal growth factor receptor in human pulmonary epithelial cells

(2014) Philippe Dje N'Guessan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Genetics Shape the Gut Microbiome

(2014) Julia K. Goodrich et al.   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Influenza Promotes Pneumococcal Growth during Coinfection by Providing Host Sialylated Substrates as a Nutrient Source

(2014) Steven J. Siegel et al.   Cell Host & Microbe

Defining dysbiosis and its influence on host immunity and disease

(2014) Charisse Petersen et al.   CELLULAR MICROBIOLOGY

The Role of Influenza and Parainfluenza Infections in Nasopharyngeal Pneumococcal Acquisition Among Young Children

(2014) Carlos G. Grijalva et al.   CLINICAL INFECTIOUS DISEASES

Biological significance of short-chain fatty acid metabolism by the intestinal microbiome

(2014) Elena Puertollano et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children

(2014) Susan V. Lynch et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Children with asthma by school age display aberrant immune responses to pathogenic airway bacteria as infants

(2014) Jeppe Madura Larsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations

(2014) Kirsten M. Kloepfer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Analysis of Culture-Dependent versus Culture-Independent Techniques for Identification of Bacteria in Clinically Obtained Bronchoalveolar Lavage Fluid

(2014) R. P. Dickson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

High Nasopharyngeal Pneumococcal Density, Increased by Viral Coinfection, Is Associated With Invasive Pneumococcal Pneumonia

(2014) Nicole Wolter et al.   JOURNAL OF INFECTIOUS DISEASES

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

Biogeography and individuality shape function in the human skin metagenome

(2014) Julia Oh et al.   NATURE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

(2014) Eva S Gollwitzer et al.   NATURE MEDICINE

Diet and host–microbial crosstalk in postnatal intestinal immune homeostasis

(2014) Nitya Jain et al.   Nature Reviews Gastroenterology & Hepatology

Gut microbiota and allergy: the importance of the pregnancy period

(2014) Thomas R. Abrahamsson et al.   PEDIATRIC RESEARCH

Potentially Pathogenic Airway Bacteria and Neutrophilic Inflammation in Treatment Resistant Severe Asthma

(2014) Benjamin J. Green et al.   PLoS One

Changes in the Lung Microbiome following Lung Transplantation Include the Emergence of Two Distinct Pseudomonas Species with Distinct Clinical Associations

(2014) Robert P. Dickson et al.   PLoS One

Changes in the Bacterial Microbiota in Gut, Blood, and Lungs following Acute LPS Instillation into Mice Lungs

(2014) Marc A. Sze et al.   PLoS One

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

Identifying Gut Microbe-Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice

(2014) J. J. Faith et al.   Science Translational Medicine

Diet and the development of the human intestinal microbiome

(2014) Noah Voreades et al.   Frontiers in Microbiology

Bacterial microbiome of lungs in COPD

(2014) Don Sin et al.   International Journal of Chronic Obstructive Pulmonary Disease

The role of macrolides in asthma: current evidence and future directions

(2014) Ernie H C Wong et al.   Lancet Respiratory Medicine

The Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma

(2013) Elena Goleva et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

(2013) Alison Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Low gut microbiota diversity in early infancy precedes asthma at school age

(2013) T. R. Abrahamsson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Staphylococcal enterotoxin sensitization in a community-based population: a potential role in adult-onset asthma

(2013) W.-J. Song et al.   CLINICAL AND EXPERIMENTAL ALLERGY

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

The microbiome and regulation of mucosal immunity

(2013) Andrew J. McDermott et al.   IMMUNOLOGY

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma

(2013) Michael C. Peters et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

High throughput sequencing methods and analysis for microbiome research

(2013) Julia M. Di Bella et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Habitual Dietary Intake Is Associated with Stool Microbiota Composition in Monozygotic Twins

(2013) Catarina D. Simões et al.   JOURNAL OF NUTRITION

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Pneumococcal Bacterial Load Colonization as a Marker of Mixed Infection in Children With Alveolar Community-acquired Pneumonia and Respiratory Syncytial Virus or Rhinovirus Infection

(2013) Susanna Esposito et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Probiotic Administration in Early Life, Atopy, and Asthma: A Meta-analysis of Clinical Trials

(2013) N. Elazab et al.   PEDIATRICS

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

(2013) M. I. Smith et al.   SCIENCE

The impact of azithromycin therapy on the airway microbiota in asthma

(2013) Mariel Slater et al.   THORAX

The emerging world of the fungal microbiome

(2013) Gary B. Huffnagle et al.   TRENDS IN MICROBIOLOGY

A Guide to Enterotypes across the Human Body: Meta-Analysis of Microbial Community Structures in Human Microbiome Datasets

(2013) Omry Koren et al.   PLoS Computational Biology

Viral and Bacterial Interactions in the Upper Respiratory Tract

(2013) Astrid A. T. M. Bosch et al.   PLoS Pathogens

Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation

(2013) Leopoldo N Segal et al.   Microbiome

Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships

(2013) Ian H McHardy et al.   Microbiome

A qPCR-based metric of Th2 airway inflammation in asthma

(2013) Nirav R Bhakta et al.   Clinical and Translational Allergy

Th17-stimulating Protein Vaccines Confer Protection againstPseudomonas aeruginosaPneumonia

(2012) Weihui Wu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areas

(2012) A. M. Karvonen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

(2012) Shannon L Russell et al.   EMBO REPORTS

Architectural design influences the diversity and structure of the built environment microbiome

(2012) Steven W Kembel et al.   ISME Journal

Specific IgE against Staphylococcus aureus enterotoxins: An independent risk factor for asthma

(2012) Claus Bachert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Early-life environmental determinants of allergic diseases and the wider pandemic of inflammatory noncommunicable diseases

(2012) Susan L. Prescott   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma-associated differences in microbial composition of induced sputum

(2012) Pradeep Reddy Marri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Voriconazole and Posaconazole Improve Asthma Severity in Allergic Bronchopulmonary Aspergillosis and Severe Asthma with Fungal Sensitization

(2012) Livingstone Chishimba et al.   JOURNAL OF ASTHMA

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Asthma phenotypes: the evolution from clinical to molecular approaches

(2012) Sally E Wenzel   NATURE MEDICINE

The oral microbiome in health and disease

(2012) William G. Wade   PHARMACOLOGICAL RESEARCH

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

(2012) T. Olszak et al.   SCIENCE

CombinedHaemophilus influenzaerespiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma

(2012) Ama-Tawiah Essilfie et al.   THORAX

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

(2011) Tina Herbst et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macrolides in the treatment of asthma

(2011) James T. Good et al.   CURRENT OPINION IN PULMONARY MEDICINE

The genetics of asthma and allergic disease: a 21st century perspective

(2011) Carole Ober et al.   IMMUNOLOGICAL REVIEWS

Experimental and analytical tools for studying the human microbiome

(2011) Justin Kuczynski et al.   NATURE REVIEWS GENETICS

Prenatal or Early-Life Exposure to Antibiotics and Risk of Childhood Asthma: A Systematic Review

(2011) W. Murk et al.   PEDIATRICS

Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease

(2011) Ama-Tawiah Essilfie et al.   PLoS Pathogens

Moving pictures of the human microbiome

(2011) J Gregory Caporaso et al.   GENOME BIOLOGY

IgE Sensitization toAspergillus fumigatusIs Associated with Reduced Lung Function in Asthma

(2010) Abbie Fairs et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Update on Infection and Antibiotics in Asthma

(2010) Donald R. Rollins et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Man's best friend? The effect of pet ownership on house dust microbial communities

(2010) Kei E. Fujimura et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

(2010) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Role of viral respiratory infections in asthma and asthma exacerbations

(2010) William W Busse et al.   LANCET

Association Between Nasopharyngeal Load of Streptococcus pneumoniae, Viral Coinfection, and Radiologically Confirmed Pneumonia in Vietnamese Children

(2010) Huong Thi Thu Vu et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Disordered Microbial Communities in Asthmatic Airways

(2010) Markus Hilty et al.   PLoS One

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative Analyses of the Bacterial Microbiota of the Human Nostril and Oropharynx

(2010) Katherine Lemon   mBio

T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma

(2009) Prescott G. Woodruff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Randomized Controlled Trial of Oral Antifungal Treatment for Severe Asthma with Fungal Sensitization

(2008) David W. Denning et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE