Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis
出版年份 2020 全文链接
标题
Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis
作者
关键词
-
出版物
Cells
Volume 9, Issue 4, Pages 927
出版商
MDPI AG
发表日期
2020-04-13
DOI
10.3390/cells9040927
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Soya-cerebroside inhibits VEGF-facilitated angiogenesis in endothelial progenitor cells
- (2020) Hsiang-Ping Lee et al. FOOD AND AGRICULTURAL IMMUNOLOGY
- Role of Inflammation and the Immune System in the Progression of Osteoarthritis
- (2019) Jennifer E. Woodell‐May et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Topical Treatment of Degenerative Knee Osteoarthritis
- (2018) Zengdong Meng et al. AMERICAN JOURNAL OF THE MEDICAL SCIENCES
- Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy
- (2018) Purva Singh et al. Annals of the New York Academy of Sciences
- Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis
- (2018) Ju-Ryoung Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Treatment with Obestatin—A Ghrelin Gene-Encoded Peptide—Reduces the Severity of Experimental Colitis Evoked by Trinitrobenzene Sulfonic Acid
- (2018) Katarzyna Konarska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Macrophage plasticity, polarization, and function in health and disease
- (2018) Abbas Shapouri-Moghaddam et al. JOURNAL OF CELLULAR PHYSIOLOGY
- NLRP3 as a potentially novel biomarker for the management of osteoarthritis
- (2018) M.J. McAllister et al. OSTEOARTHRITIS AND CARTILAGE
- Sp1 Plays an Important Role in Vascular Calcification Both In Vivo and In Vitro
- (2018) Xinyu Zhang et al. Journal of the American Heart Association
- Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis
- (2018) Cuicui Wang et al. Journal of Orthopaedic Translation
- Glucose suppresses IL-1β-induced MMP-1 expression through the FAK, MEK, ERK, and AP-1 signaling pathways
- (2018) Tsung-Ju Wu et al. ENVIRONMENTAL TOXICOLOGY
- Repair of Damaged Articular Cartilage: Current Approaches and Future Directions
- (2018) Ekaterina Medvedeva et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Plumbagin suppresses endothelial progenitor cell-related angiogenesis in vitro and in vivo
- (2018) Hsiang-Ping Lee et al. Journal of Functional Foods
- Changes of articular cartilage and subchondral bone after extracorporeal shockwave therapy in osteoarthritis of the knee
- (2017) Ching-Jen Wang et al. International Journal of Medical Sciences
- Physiological exercise loading suppresses post-traumatic osteoarthritis progression via an increase in bone morphogenetic proteins expression in an experimental rat knee model
- (2017) H. Iijima et al. OSTEOARTHRITIS AND CARTILAGE
- Knee osteoarthritis has doubled in prevalence since the mid-20th century
- (2017) Ian J. Wallace et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Osteoarthritis: toward a comprehensive understanding of pathological mechanism
- (2017) Di Chen et al. Bone Research
- Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis
- (2017) Sonia Nasi et al. Frontiers in Pharmacology
- Interleukin-1 Receptor Blockade Rescues Myocarditis-Associated End-Stage Heart Failure
- (2017) Giulio Cavalli et al. Frontiers in Immunology
- Soya-cerebroside, an extract of Cordyceps militaris, suppresses monocyte migration and prevents cartilage degradation in inflammatory animal models
- (2017) Shan-Chi Liu et al. Scientific Reports
- The Influence of Knee Pain Location on Symptoms, Functional Status, and Knee-related Quality of Life in Older Adults With Chronic Knee Pain
- (2016) Shawn Farrokhi et al. CLINICAL JOURNAL OF PAIN
- Interleukin-1 induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes
- (2016) S.-Y. Chien et al. CLINICAL SCIENCE
- Comparison of micro-CT post-processing methods for evaluating the trabecular bone volume fraction in a rat ACL-transection model
- (2016) K.E. Chin et al. JOURNAL OF BIOMECHANICS
- BMP signalling in skeletal development, disease and repair
- (2016) Valerie S. Salazar et al. Nature Reviews Endocrinology
- Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
- (2016) William H. Robinson et al. Nature Reviews Rheumatology
- Imbalance Between Bone Morphogenetic Protein 2 and Noggin Induces Abnormal Osteogenic Differentiation of Mesenchymal Stem Cells in Ankylosing Spondylitis
- (2016) Zhongyu Xie et al. Arthritis & Rheumatology
- Interleukin-6 and chondrocyte mineralisation act in tandem to promote experimental osteoarthritis
- (2015) Sonia Nasi et al. ANNALS OF THE RHEUMATIC DISEASES
- Multiple roles of tumor necrosis factor-alpha in fracture healing
- (2015) Jonathan M. Karnes et al. BONE
- Subchondral bone and osteoarthritis
- (2015) Thomas Funck-Brentano et al. CURRENT OPINION IN RHEUMATOLOGY
- The Interleukin-1 Balance During Encephalitis Is Associated With Clinical Severity, Blood-Brain Barrier Permeability, Neuroimaging Changes, and Disease Outcome
- (2015) Benedict Daniel Michael et al. JOURNAL OF INFECTIOUS DISEASES
- Resistin Promotes Angiogenesis in Endothelial Progenitor Cells Through Inhibition of MicroRNA206: Potential Implications for Rheumatoid Arthritis
- (2015) Chen-Ming Su et al. STEM CELLS
- The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
- (2014) Piotr Wojdasiewicz et al. MEDIATORS OF INFLAMMATION
- Bone–cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategies
- (2014) X.L. Yuan et al. OSTEOARTHRITIS AND CARTILAGE
- Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib)
- (2013) J. El-Hoss et al. BONE
- Macrophages: Supportive cells for tissue repair and regeneration
- (2013) Bénédicte Chazaud IMMUNOBIOLOGY
- Interplay between Cartilage and Subchondral Bone Contributing to Pathogenesis of Osteoarthritis
- (2013) Ashish Sharma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
- (2013) Gehua Zhen et al. NATURE MEDICINE
- Hypertrophic differentiation during chondrogenic differentiation of progenitor cells is stimulated by BMP-2 but suppressed by BMP-7
- (2013) M.M.J. Caron et al. OSTEOARTHRITIS AND CARTILAGE
- Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes
- (2013) Guangyi Li et al. ARTHRITIS RESEARCH & THERAPY
- Osteoarthritis: A disease of the joint as an organ
- (2012) Richard F. Loeser et al. ARTHRITIS AND RHEUMATISM
- Transcriptional regulation by post-transcriptional modification—Role of phosphorylation in Sp1 transcriptional activity
- (2012) Shijian Chu GENE
- Noggin suppression decreases BMP-2-induced osteogenesis of human bone marrow-derived mesenchymal stem cellsIn Vitro
- (2012) Chao Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment
- (2012) Indira Prasadam et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Bone remodelling in osteoarthritis
- (2012) David B. Burr et al. Nature Reviews Rheumatology
- Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
- (2012) F. Berenbaum OSTEOARTHRITIS AND CARTILAGE
- Bone morphogenetic protein-2-induced Wnt/beta-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
- (2012) Ioanna Papathanasiou et al. ARTHRITIS RESEARCH & THERAPY
- Inflammation in osteoarthritis
- (2011) Mary B. Goldring et al. CURRENT OPINION IN RHEUMATOLOGY
- Noggin
- (2011) Carola Krause et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development
- (2011) B. Shu et al. JOURNAL OF CELL SCIENCE
- Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?
- (2011) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- Role of Sp1 transcription factor in Interleukin-1-induced ADAMTS-4 (aggrecanase-1) gene expression in human articular chondrocytes
- (2011) Judith Sylvester et al. RHEUMATOLOGY INTERNATIONAL
- High Doses of Bone Morphogenetic Protein 2 Induce Structurally Abnormal Bone and Inflammation In Vivo
- (2011) Janette N. Zara et al. TISSUE ENGINEERING PART A
- Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis
- (2011) Gabriel N Kaufman et al. ARTHRITIS RESEARCH & THERAPY
- Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis
- (2011) Geetha Mohan et al. ARTHRITIS RESEARCH & THERAPY
- Bone Morphogenetic Proteins and articular cartilage
- (2010) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- In vitro differentiation of chondrogenic ATDC5 cells is enhanced by culturing on synthetic hydrogels with various charge densities
- (2009) Hyuck Joon Kwon et al. Acta Biomaterialia
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- Bone morphogenetic protein signaling and arthritis
- (2009) Rik J.U. Lories et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Sp1 Phosphorylation and Its Regulation of Gene Transcription
- (2009) N. Y. Tan et al. MOLECULAR AND CELLULAR BIOLOGY
- MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation – divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation
- (2009) B.-C. Sondergaard et al. OSTEOARTHRITIS AND CARTILAGE
- Should subchondral bone turnover be targeted when treating osteoarthritis?
- (2008) M.A. Karsdal et al. OSTEOARTHRITIS AND CARTILAGE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started