Bone remodelling in osteoarthritis

Decreased bone tissue mineralization can partly explain subchondral sclerosis observed in osteoarthritis

(2012) L.G.E. Cox et al.   BONE

Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations

(2012) Oran D. Kennedy et al.   BONE

Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: An in vivo microfocal computed tomography study

(2011) Sander M. Botter et al.   ARTHRITIS AND RHEUMATISM

Elevated cross-talk between subchondral bone and cartilage in osteoarthritic joints

(2011) Jun Pan et al.   BONE

Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts

(2011) Thomas F. Chan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Improving subchondral bone integrity reduces progression of cartilage damage in experimental osteoarthritis preceded by osteoporosis

(2011) M. Bellido et al.   OSTEOARTHRITIS AND CARTILAGE

Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling

(2010) A. Kadri et al.   ANNALS OF THE RHEUMATIC DISEASES

Osteoarthritic changes in canine articular cartilage, subchondral bone, and synovium fifty-four months after transection of the anterior cruciate ligament

(2010) Kenneth D. Brandt et al.   ARTHRITIS AND RHEUMATISM

Control of Dkk-1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees

(2010) Lin-Hsiu Weng et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritis in cynomolgus macaques III: Effects of age, gender, and subchondral bone thickness on the severity of disease

(2010) Cathy S. Carlson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Similarities and discrepancies in subchondral bone structure in two differently induced canine models of osteoarthritis

(2010) Femke Intema et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis

(2010) D.D. Kumarasinghe et al.   OSTEOARTHRITIS AND CARTILAGE

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis

(2010) Miriam Bellido et al.   ARTHRITIS RESEARCH & THERAPY

Cartilage loss occurs in the same subregions as subchondral bone attrition: A within-knee subregion-matched approach from the multicenter osteoarthritis study

(2009) T. Neogi et al.   ARTHRITIS AND RHEUMATISM

Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production

(2009) Denis Couchourel et al.   ARTHRITIS AND RHEUMATISM

In situ measurement of transport between subchondral bone and articular cartilage

(2009) Jun Pan et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis

(2009) S. Kwan Tat et al.   RHEUMATOLOGY

Bisphosphonates for osteoarthritis prevention: "Holy Grail" or not?

(2008) K. G Saag   ANNALS OF THE RHEUMATIC DISEASES

Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis

(2008) Jennifer Hwang et al.   ARTHRITIS AND RHEUMATISM

Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis

(2008) A. Kadri et al.   ARTHRITIS AND RHEUMATISM

A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models

(2008) Yvonne H Sniekers et al.   BMC MUSCULOSKELETAL DISORDERS

Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: Influence of osteotropic factors

(2008) Steeve Kwan Tat et al.   BONE

Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort

(2008) S. Reichenbach et al.   OSTEOARTHRITIS AND CARTILAGE

Should subchondral bone turnover be targeted when treating osteoarthritis?

(2008) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3T

(2008) R.I. Bolbos et al.   OSTEOARTHRITIS AND CARTILAGE

ADAMTS5−/− mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes

(2008) S.M. Botter et al.   OSTEOARTHRITIS AND CARTILAGE

Enhanced Expression of Osteocalcin mRNA in Human Osteoarthritic Trabecular Bone of the Proximal Femur Is Associated with Decreased Expression of Interleukin-6 and Interleukin-11 mRNA

(2006) Julia S. Kuliwaba et al.   JOURNAL OF BONE AND MINERAL RESEARCH