Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-  pathway

(2012) A. Lorts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

(2012) Peter M van der Kraan et al.   ARTHRITIS RESEARCH & THERAPY

Alterations in periarticular bone and cross talk between subchondral bone and articular cartilage in osteoarthritis

(2012) Steven R. Goldring   Therapeutic Advances in Musculoskeletal Disease

Bone marrow-derived mesenchymal stem cells from early diffuse systemic sclerosis exhibit a paracrine machinery and stimulate angiogenesis in vitro

(2011) S. Guiducci et al.   ANNALS OF THE RHEUMATIC DISEASES

ALK1 as an emerging target for antiangiogenic therapy of cancer

(2011) S. I. Cunha et al.   BLOOD

Osteochondral alterations in osteoarthritis

(2011) Sunita Suri et al.   BONE

Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis

(2011) Ichiro Sekiya et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Pluripotency of mesenchymal cells derived from synovial fluid in patients with temporomandibular joint disorder

(2011) Noriaki Koyama et al.   LIFE SCIENCES

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Identification of a central role for complement in osteoarthritis

(2011) Qian Wang et al.   NATURE MEDICINE

Osteoarthritis year 2010 in review: non-pharmacologic therapy

(2011) G.A. Hawker et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis year 2010 in review: pharmacological therapies

(2011) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis year 2010 in review: pathomechanisms

(2011) W.B. van den Berg   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis year 2011 in review: biology

(2011) M. Lotz   OSTEOARTHRITIS AND CARTILAGE

Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells

(2011) X. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears

(2011) Verena Stein et al.   RHEUMATOLOGY INTERNATIONAL

In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat

(2010) Michael D. Jones et al.   ARTHRITIS AND RHEUMATISM

Inhibition of Sca-1-Positive Skeletal Stem Cell Recruitment by Alendronate Blunts the Anabolic Effects of Parathyroid Hormone on Bone Remodeling

(2010) Xiangwei Wu et al.   Cell Stem Cell

Smad3 Prevents β-Catenin Degradation and Facilitates β-Catenin Nuclear Translocation in Chondrocytes

(2010) Ming Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo

(2010) James R Edwards et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Camurati-engelmann disease: Unique variant featuring a novel mutation in TGFβ1 encoding transforming growth factor beta 1 and a missense change in TNFSF11 encoding RANK ligand

(2010) Michael P Whyte et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The basic science of the subchondral bone

(2010) Henning Madry et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

The bone–cartilage unit in osteoarthritis

(2010) Rik J. Lories et al.   Nature Reviews Rheumatology

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders

(2010) Rita Dreier   ARTHRITIS RESEARCH & THERAPY

Increase in ALK1/ALK5 Ratio as a Cause for Elevated MMP-13 Expression in Osteoarthritis in Humans and Mice

(2009) E. N. Blaney Davidson et al.   JOURNAL OF IMMUNOLOGY

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Subchondral fluid dynamics in a model of osteoarthritis: use of dynamic contrast-enhanced magnetic resonance imaging

(2009) J.H. Lee et al.   OSTEOARTHRITIS AND CARTILAGE

TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis

(2009) P.M. van der Kraan et al.   OSTEOARTHRITIS AND CARTILAGE

Evaluation of Tetrandrine Sustained Release Calcium Alginate Gel Beads In Vitro and In Vivo

(2009) Yan MA et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized

(2009) David J Hunter et al.   ARTHRITIS RESEARCH & THERAPY

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice

(2008) Qiuqian Wu et al.   ARTHRITIS AND RHEUMATISM

Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: Effects of morphine and rofecoxib

(2008) Kristina Ängeby Möller et al.   JOURNAL OF NEUROSCIENCE METHODS

Role of Bone in Osteoarthritis Pathogenesis

(2008) Steven R. Goldring   MEDICAL CLINICS OF NORTH AMERICA

Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritis

(2008) S. Amin et al.   OSTEOARTHRITIS AND CARTILAGE