Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis
出版年份 2018 全文链接
标题
Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 3, Pages 674
出版商
MDPI AG
发表日期
2018-02-28
DOI
10.3390/ijms19030674
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Clodronate as a Therapeutic Strategy against Osteoarthritis
- (2017) Maria Valenti et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nitric Oxide Mediates Crosstalk between Interleukin 1β and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression
- (2017) Leilei Zhong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Efficacy and safety of adalimumab by intra-articular injection for moderate to severe knee osteoarthritis: An open-label randomized controlled trial
- (2017) Jianping Wang JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway
- (2017) Na Qin et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
- (2017) Ok Hee Jeon et al. NATURE MEDICINE
- Recent advances in the understanding of molecular mechanisms of cartilage degeneration, synovitis and subchondral bone changes in osteoarthritis
- (2016) Yingliang Wei et al. CONNECTIVE TISSUE RESEARCH
- Impaired muscle function in a mouse surgical model of post-traumatic osteoarthritis
- (2016) C. van der Poel et al. OSTEOARTHRITIS AND CARTILAGE
- When Is Osteonecrosis Not Osteonecrosis?: Adjudication of Reported Serious Adverse Joint Events in the Tanezumab Clinical Development Program
- (2016) Marc C. Hochberg et al. Arthritis & Rheumatology
- Bisphosphonates therapy for osteoarthritis: a meta-analysis of randomized controlled trials
- (2016) R. L. Xing et al. SpringerPlus
- Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
- (2015) Hyun Hwang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of HIF-1α and HIF-2α in osteoarthritis
- (2015) Fang-Jie Zhang et al. JOINT BONE SPINE
- Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α
- (2015) Wuyin Li et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Osteoarthritis
- (2015) S Glyn-Jones et al. LANCET
- Interleukin-6 and tumor necrosis factor alpha in synovial fluid are associated with progression of radiographic knee osteoarthritis in subjects with previous meniscectomy
- (2015) S. Larsson et al. OSTEOARTHRITIS AND CARTILAGE
- Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2
- (2015) Shurei Sugita et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis
- (2015) Zhaoyang Liu et al. Science Signaling
- A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis
- (2015) Zhaoyang Liu et al. Science Signaling
- Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: a randomised, multicentre, double-blind, placebo-controlled trial
- (2014) X Chevalier et al. ANNALS OF THE RHEUMATIC DISEASES
- Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain
- (2014) Thomas J Schnitzer et al. ANNALS OF THE RHEUMATIC DISEASES
- Regulation of the Catabolic Cascade in Osteoarthritis by the Zinc-ZIP8-MTF1 Axis
- (2014) Jin-Hong Kim et al. CELL
- The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
- (2014) Piotr Wojdasiewicz et al. MEDIATORS OF INFLAMMATION
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Bone–cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategies
- (2014) X.L. Yuan et al. OSTEOARTHRITIS AND CARTILAGE
- Effects of intra-articular clodronate in the treatment of knee osteoarthritis: results of a double-blind, randomized placebo-controlled trial
- (2014) Maurizio Rossini et al. RHEUMATOLOGY INTERNATIONAL
- Strontium ranelate reduces cartilage degeneration and subchondral bone remodeling in rat osteoarthritis model
- (2013) De-gang Yu et al. ACTA PHARMACOLOGICA SINICA
- Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss
- (2013) Jean-Pierre Pelletier et al. ANNALS OF THE RHEUMATIC DISEASES
- Alendronate protects against articular cartilage erosion by inhibiting subchondral bone loss in ovariectomized rats
- (2013) Songsong Zhu et al. BONE
- Bearing arms against osteoarthritis and sarcopenia: when cartilage and skeletal muscle find common interest in talking together
- (2013) Frédéric De Ceuninck et al. DRUG DISCOVERY TODAY
- A current review of molecular mechanisms regarding osteoarthritis and pain
- (2013) Andrew S. Lee et al. GENE
- The NF-κB signalling pathway in osteoarthritis
- (2013) Stella Rigoglou et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- WNT signaling in bone homeostasis and disease: from human mutations to treatments
- (2013) Roland Baron et al. NATURE MEDICINE
- Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: Implication for osteoarthritis therapy
- (2013) Amar S. More et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Are Bisphosphonates Effective in the Treatment of Osteoarthritis Pain? A Meta-Analysis and Systematic Review
- (2013) Alison J. Davis et al. PLoS One
- Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development
- (2013) Y. Hosaka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of Changes in Extracellular Matrix of Cartilage in the Presence of Inflammation on the Pathology of Osteoarthritis
- (2013) Maricela Maldonado et al. Biomed Research International
- Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial
- (2012) Laura Louise Laslett et al. ANNALS OF THE RHEUMATIC DISEASES
- Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial
- (2012) Jean-Yves Reginster et al. ANNALS OF THE RHEUMATIC DISEASES
- A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee
- (2012) Marie-Pierre Hellio le Graverand et al. ANNALS OF THE RHEUMATIC DISEASES
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Dystrophin and utrophin “double knockout” dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities
- (2012) Christian Isaac et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
- (2012) Dong Sohn et al. ARTHRITIS RESEARCH & THERAPY
- Muscle Impairments in Patients With Knee Osteoarthritis
- (2012) Ali H. Alnahdi et al. Sports Health-A Multidisciplinary Approach
- Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification
- (2011) Gust Verbruggen et al. ANNALS OF THE RHEUMATIC DISEASES
- Autophagy activation by rapamycin reduces severity of experimental osteoarthritis
- (2011) Beatriz Caramés et al. ANNALS OF THE RHEUMATIC DISEASES
- Increased inflammatory cytokine expression in the vastus lateralis of patients with knee osteoarthritis
- (2011) Itamar Levinger et al. ARTHRITIS AND RHEUMATISM
- Autophagy modulates osteoarthritis-related gene expression in human chondrocytes
- (2011) Hiroshi Sasaki et al. ARTHRITIS AND RHEUMATISM
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- OARSI-FDA initiative: defining the disease state of osteoarthritis
- (2011) N.E. Lane et al. OSTEOARTHRITIS AND CARTILAGE
- Anabolic/Catabolic Balance in Pathogenesis of Osteoarthritis: Identifying Molecular Targets
- (2011) Michael B. Mueller et al. PM&R
- Aging and its effects on inflammation in skeletal muscle at rest and following exercise-induced muscle injury
- (2010) Jonathan Peake et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Osteoarthritis: can anti-cytokine therapy play a role in treatment?
- (2010) Ana Luisa G. Calich et al. CLINICAL RHEUMATOLOGY
- Characterization of apoptosis in articular cartilage derived from the knee joints of patients with osteoarthritis
- (2010) Giuseppe Musumeci et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- (2010) Taku Saito et al. NATURE MEDICINE
- Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
- (2010) Siyoung Yang et al. NATURE MEDICINE
- Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
- (2010) Mohit Kapoor et al. Nature Reviews Rheumatology
- Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis
- (2010) M. Güler-Yüksel et al. OSTEOARTHRITIS AND CARTILAGE
- Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease
- (2010) B.W. Strassle et al. OSTEOARTHRITIS AND CARTILAGE
- Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees
- (2010) Y. Wang et al. RHEUMATOLOGY
- Effects of diacerein at the molecular level in the osteoarthritis disease process
- (2010) Johanne Martel-Pelletier et al. Therapeutic Advances in Musculoskeletal Disease
- Erosive osteoarthritis of the hand: clinical experience with anakinra
- (2009) L Bacconnier et al. ANNALS OF THE RHEUMATIC DISEASES
- Regulation of autophagy in human and murine cartilage: Hypoxia-inducible factor 2 suppresses chondrocyte autophagy
- (2009) Jolene Bohensky et al. ARTHRITIS AND RHEUMATISM
- Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebo-controlled study
- (2009) X. Chevalier et al. ARTHRITIS AND RHEUMATISM
- Matrix metalloproteinase 13âdeficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
- (2009) C. B. Little et al. ARTHRITIS AND RHEUMATISM
- Molecular regulation of skeletal muscle mass
- (2009) Aaron P Russell CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes
- (2009) R. Ahmad et al. JOURNAL OF IMMUNOLOGY
- Muscle weakness causes joint degeneration in rabbits
- (2009) A. Rehan Youssef et al. OSTEOARTHRITIS AND CARTILAGE
- Physical Function and Properties of Quadriceps Femoris Muscle in Men With Knee Osteoarthritis
- (2008) Tuomas Liikavainio et al. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
- Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis
- (2008) Jennifer Hwang et al. ARTHRITIS AND RHEUMATISM
- Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice
- (2008) Mei Zhu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Role of Bone in Osteoarthritis Pathogenesis
- (2008) Steven R. Goldring MEDICAL CLINICS OF NORTH AMERICA
- Role of Muscle in the Genesis and Management of Knee Osteoarthritis
- (2008) Kim L. Bennell et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13
- (2008) David Long et al. ARTHRITIS RESEARCH & THERAPY
- Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-κBp65-specific siRNA
- (2007) L.X. Chen et al. OSTEOARTHRITIS AND CARTILAGE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search