Harnessing the immune system via FcγR function in immune therapy: a pathway to next‐gen mAbs
出版年份 2020 全文链接
标题
Harnessing the immune system
via
FcγR function in immune therapy: a pathway to next‐gen mAbs
作者
关键词
-
出版物
IMMUNOLOGY AND CELL BIOLOGY
Volume 98, Issue 4, Pages 287-304
出版商
Wiley
发表日期
2020-03-11
DOI
10.1111/imcb.12326
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity
- (2020) Anna B. Morris et al. IMMUNITY
- Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation
- (2019) Josée Golay et al. BLOOD
- A stable engineered human IgG3 antibody with decreased aggregation during antibody expression and low pH stress
- (2019) Seiji Saito et al. PROTEIN SCIENCE
- An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes
- (2019) Kevan C. Herold et al. NEW ENGLAND JOURNAL OF MEDICINE
- TRIM21—From Intracellular Immunity to Therapy
- (2019) Stian Foss et al. Frontiers in Immunology
- Antibodies to watch in 2020
- (2019) Hélène Kaplon et al. mAbs
- The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity
- (2019) Sina Gordan et al. Cell Reports
- Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies
- (2018) Xiaojie Yu et al. CANCER CELL
- The binding of an anti-PD-1 antibody to FcγRΙ has a profound impact on its biological functions
- (2018) Tong Zhang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets
- (2018) Matthew H. Bakalar et al. CELL
- Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
- (2018) Spencer A. Freeman et al. CELL
- Update on Fc receptor-like (FCRL) family: new immunoregulatory players in health and diseases
- (2018) Davood Rostamzadeh et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Market watch: Top drugs and companies by sales in 2017
- (2018) Lisa Urquhart NATURE REVIEWS DRUG DISCOVERY
- The Contribution of Non-Professional Antigen-Presenting Cells to Immunity and Tolerance in the Liver
- (2018) Christina Mehrfeld et al. Frontiers in Immunology
- Picket-fences in the plasma membrane: functions in immune cells and phagocytosis
- (2018) Sivakami M. Mylvaganam et al. Seminars in Immunopathology
- Targeting FcRn to Generate Antibody-Based Therapeutics
- (2018) E. Sally Ward et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1
- (2018) Jessica C. Anania et al. Frontiers in Immunology
- Immune Checkpoints as Therapeutic Targets in Autoimmunity
- (2018) Christopher Paluch et al. Frontiers in Immunology
- CD32 Ligation Promotes the Activation of CD4+ T Cells
- (2018) María Pía Holgado et al. Frontiers in Immunology
- Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms
- (2017) Kirstie L. S. Cleary et al. JOURNAL OF IMMUNOLOGY
- A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies
- (2017) E Casey et al. LEUKEMIA
- Characterization of the Anti–PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice
- (2017) Elena Burova et al. MOLECULAR CANCER THERAPEUTICS
- CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
- (2017) Benjamin Descours et al. NATURE
- Nivolumab as Programmed Death-1 (PD-1) Inhibitor for Targeted Immunotherapy in Tumor
- (2017) Liting Guo et al. Journal of Cancer
- Fcγ Receptor Heterogeneity in Leukocyte Functional Responses
- (2017) Carlos Rosales Frontiers in Immunology
- Mouse Liver Sinusoidal Endothelium Eliminates HIV-Like Particles from Blood at a Rate of 100 Million per Minute by a Second-Order Kinetic Process
- (2017) Jessica M. Mates et al. Frontiers in Immunology
- Atezolizumab: A PD-L1–Blocking Antibody for Bladder Cancer
- (2016) Brant A. Inman et al. CLINICAL CANCER RESEARCH
- Harnessing Fc receptor biology in the design of therapeutic antibodies
- (2016) Peter Sondermann et al. CURRENT OPINION IN IMMUNOLOGY
- Immunoglobulin isotype knowledge and application to Fc engineering
- (2016) Randall J Brezski et al. CURRENT OPINION IN IMMUNOLOGY
- Targeting B cells in treatment of autoimmunity
- (2016) S Elizabeth Franks et al. CURRENT OPINION IN IMMUNOLOGY
- Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody
- (2016) Di Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor–Mediated Cross-Linking
- (2016) Marije B. Overdijk et al. JOURNAL OF IMMUNOLOGY
- Dimeric FcγR Ectodomains as Probes of the Fc Receptor Function of Anti-Influenza Virus IgG
- (2016) Bruce D. Wines et al. JOURNAL OF IMMUNOLOGY
- Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies
- (2015) Ann L. White et al. CANCER CELL
- Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect
- (2015) David J. DiLillo et al. CELL
- Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling
- (2015) Andrew Getahun et al. IMMUNOLOGICAL REVIEWS
- The biology of the classical Fcγ receptors in non-hematopoietic cells
- (2015) Clark L. Anderson et al. IMMUNOLOGICAL REVIEWS
- Fcγ receptors: genetic variation, function, and disease
- (2015) Chantal E. Hargreaves et al. IMMUNOLOGICAL REVIEWS
- Mouse and human FcR effector functions
- (2015) Pierre Bruhns et al. IMMUNOLOGICAL REVIEWS
- Trastuzumab Triggers Phagocytic Killing of High HER2 Cancer Cells In Vitro and In Vivo by Interaction with Fcγ Receptors on Macrophages
- (2015) Yun Shi et al. JOURNAL OF IMMUNOLOGY
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- (2015) Stefanie Derer et al. JOURNAL OF IMMUNOLOGY
- Inhibitory FcγRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering
- (2015) Yuki Iwayanagi et al. JOURNAL OF IMMUNOLOGY
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- (2015) Xiaoyu Yang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Obinutuzumab as frontline treatment of chronic lymphocytic leukemia: updated results of the CLL11 study
- (2015) V Goede et al. LEUKEMIA
- Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
- (2015) Masato Kiyoshi et al. Nature Communications
- Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody
- (2015) R. Stewart et al. Cancer Immunology Research
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- (2015) Jennifer D. Könitzer et al. PLoS One
- Dynamics of Inter-heavy Chain Interactions in Human Immunoglobulin G (IgG) Subclasses Studied by Kinetic Fab Arm Exchange
- (2014) Theo Rispens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fcγ Receptor Dependency of Agonistic CD40 Antibody in Lymphoma Therapy Can Be Overcome through Antibody Multimerization
- (2014) Ann L. White et al. JOURNAL OF IMMUNOLOGY
- Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection
- (2014) P. Acharya et al. JOURNAL OF VIROLOGY
- Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation
- (2013) Balthasar A. Heesters et al. IMMUNITY
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- (2013) Fabricio Montalvao et al. JOURNAL OF CLINICAL INVESTIGATION
- Impact of Immune Complex Size and Glycosylation on IgG Binding to Human Fc Rs
- (2013) A. Lux et al. JOURNAL OF IMMUNOLOGY
- Polymorphisms and Interspecies Differences of the Activating and Inhibitory Fc RII of Macaca nemestrina Influence the Binding of Human IgG Subclasses
- (2013) H. M. Trist et al. JOURNAL OF IMMUNOLOGY
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- (2013) Maja Pučić Baković et al. JOURNAL OF PROTEOME RESEARCH
- Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity
- (2013) Stefanie Derer et al. mAbs
- Clinical targeting of the TNF and TNFR superfamilies
- (2013) Michael Croft et al. NATURE REVIEWS DRUG DISCOVERY
- Engineered antibody Fc variant with selectively enhanced Fc RIIb binding over both Fc RIIaR131 and Fc RIIaH131
- (2013) F. Mimoto et al. PROTEIN ENGINEERING DESIGN & SELECTION
- EGFR expression levels affect the mode of action of EGFR-targeting monoclonal antibodies
- (2013) Stefanie Derer et al. OncoImmunology
- Results of a Phase 1 Study of AME-133v (LY2469298), an Fc-Engineered Humanized Monoclonal Anti-CD20 Antibody, in FcγRIIIa-Genotyped Patients with Previously Treated Follicular Lymphoma
- (2012) Andres Forero-Torres et al. CLINICAL CANCER RESEARCH
- Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
- (2012) Seung Y. Chu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Fc RIIb on Liver Sinusoidal Endothelium Clears Small Immune Complexes
- (2012) L. P. Ganesan et al. JOURNAL OF IMMUNOLOGY
- Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1
- (2012) Thomas C. Nesspor et al. JOURNAL OF MOLECULAR RECOGNITION
- Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond
- (2012) P. Mark Hogarth et al. NATURE REVIEWS DRUG DISCOVERY
- Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fc receptor engagement
- (2012) F. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction with Fc RIIB Is Critical for the Agonistic Activity of Anti-CD40 Monoclonal Antibody
- (2011) A. L. White et al. JOURNAL OF IMMUNOLOGY
- Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer
- (2011) José Baselga et al. NEW ENGLAND JOURNAL OF MEDICINE
- Functional Expression of IgG-Fc Receptors in Human Airway Smooth Muscle Cells
- (2010) YuXiu C. Xia et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity
- (2010) E. Mossner et al. BLOOD
- Long-lasting antitumor protection by anti-CD20 antibody through cellular immune response
- (2010) R. Abes et al. BLOOD
- Superior In vivo Efficacy of Afucosylated Trastuzumab in the Treatment of HER2-Amplified Breast Cancer
- (2010) Teemu T. Junttila et al. CANCER RESEARCH
- Reciprocal Regulation of Activating and Inhibitory Fc Receptors by TLR7/8 Activation: Implications for Tumor Immunotherapy
- (2010) J. P. Butchar et al. CLINICAL CANCER RESEARCH
- B-Cell Depletion In Vitro and In Vivo with an Afucosylated Anti-CD19 Antibody
- (2010) R. Herbst et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab
- (2009) S. P. Hilchey et al. BLOOD
- Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage Fc RI, Fc RIII, and Fc RIV
- (2008) V. Minard-Colin et al. BLOOD
- Specificity and affinity of human Fc receptors and their polymorphic variants for human IgG subclasses
- (2008) P. Bruhns et al. BLOOD
- The clinical pharmacology of therapeutic monoclonal antibodies in the treatment of malignancy; have the magic bullets arrived?
- (2008) Barrett W. Newsome et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia
- (2008) H. M. Horton et al. CANCER RESEARCH
- Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms
- (2008) Jette Wypych et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies
- (2008) Seung Y. Chu et al. MOLECULAR IMMUNOLOGY
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