A stable engineered human IgG3 antibody with decreased aggregation during antibody expression and low pH stress
出版年份 2019 全文链接
标题
A stable engineered human IgG3 antibody with decreased aggregation during antibody expression and low pH stress
作者
关键词
-
出版物
PROTEIN SCIENCE
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-03-05
DOI
10.1002/pro.3598
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Antibodies to watch in 2018
- (2018) Hélène Kaplon et al. mAbs
- Structural characterization of the Man5 glycoform of human IgG3 Fc
- (2017) Ishan S. Shah et al. MOLECULAR IMMUNOLOGY
- Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice
- (2017) Rens Braster et al. PLoS One
- Immunogenicity of Therapeutic Protein Aggregates
- (2016) Ehab M. Moussa et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Hinge-Region O-Glycosylation of Human Immunoglobulin G3 (IgG3)
- (2015) Rosina Plomp et al. MOLECULAR & CELLULAR PROTEOMICS
- Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1
- (2015) Lai Sum Leoh et al. MOLECULAR IMMUNOLOGY
- Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases
- (2015) Vashti Irani et al. MOLECULAR IMMUNOLOGY
- Conformational and Colloidal Stabilities of Isolated Constant Domains of Human Immunoglobulin G and Their Impact on Antibody Aggregation under Acidic Conditions
- (2015) Seiki Yageta et al. MOLECULAR PHARMACEUTICS
- Dynamics of Inter-heavy Chain Interactions in Human Immunoglobulin G (IgG) Subclasses Studied by Kinetic Fab Arm Exchange
- (2014) Theo Rispens et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination
- (2014) N. L. Yates et al. Science Translational Medicine
- IgG Subclasses and Allotypes: From Structure to Effector Functions
- (2014) Gestur Vidarsson et al. Frontiers in Immunology
- An IgG3 switch variant of rituximab mediates enhanced complement-dependent cytotoxicity against tumour cells with low CD20 expression levels
- (2013) Thies Rösner et al. BRITISH JOURNAL OF HAEMATOLOGY
- Stability engineering of the human antibody repertoire
- (2013) Romain Rouet et al. FEBS LETTERS
- IgG2 Fc structure and the dynamic features of the IgG CH2–CH3 interface
- (2013) Alexey Teplyakov et al. MOLECULAR IMMUNOLOGY
- Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress
- (2013) Takahiko Ito et al. PROTEIN SCIENCE
- Excipients Differentially Influence the Conformational Stability and Pretransition Dynamics of Two IgG1 Monoclonal Antibodies
- (2012) Santosh V. Thakkar et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
- (2011) Nigel M. Stapleton et al. Nature Communications
- Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition
- (2010) Sanjay B. Hari et al. BIOCHEMISTRY
- Aggregation-Prone Motifs in Human Immunoglobulin G
- (2009) Naresh Chennamsetty et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Difference in the Complement Activation Site of Human IgG1 and IgG3
- (2009) T. E. Michaelsen et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities
- (2008) A. Natsume et al. CANCER RESEARCH
- Protein aggregation: Pathways, induction factors and analysis
- (2008) Hanns-Christian Mahler et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs
- (2008) Sandipan Sinha et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started