Comprehensive Analysis of the Therapeutic IgG4 Antibody Pembrolizumab: Hinge Modification Blocks Half Molecule Exchange In Vitro and In Vivo

出版年份 2015 全文链接

标题

作者

关键词

half molecule (Fab arm) exchange analysis, IgG4, bispecific antibody, pembrolizumab, cancer immunotherapy, analytical biochemistry, bioanalysis, glycoprotein, immunology, biotechnology

出版物

JOURNAL OF PHARMACEUTICAL SCIENCES

Volume 104, Issue 12, Pages 4002-4014

出版商

Elsevier BV

发表日期

2015-08-27

DOI

10.1002/jps.24620

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