Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling

Tyrosine phosphatase SHP-2 mediates C-type lectin receptor–induced activation of the kinase Syk and anti-fungal TH17 responses

(2015) Zihou Deng et al.   NATURE IMMUNOLOGY

Optimal Aggregation of FcεRI with a Structurally Defined Trivalent Ligand Overrides Negative Regulation Driven by Phosphatases

(2014) Avanika Mahajan et al.   ACS Chemical Biology

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

(2014) Sanae Ben Mkaddem et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Human Peripheral IgM+ B Cells Is Transiently Inhibited by BCR-Independent Aggregation of Fc RIIB

(2014) E. M. Fournier et al.   JOURNAL OF IMMUNOLOGY

Positive and Negative Regulation of High Affinity IgE Receptor Signaling by Src Homology Region 2 Domain-Containing Phosphatase 1

(2014) K. Nakata et al.   JOURNAL OF IMMUNOLOGY

Through an ITIM-Independent Mechanism the Fc RIIB Blocks B Cell Activation by Disrupting the Colocalized Microclustering of the B Cell Receptor and CD19

(2014) L. Xu et al.   JOURNAL OF IMMUNOLOGY

Type I and type II Fc receptors regulate innate and adaptive immunity

(2014) Andrew Pincetic et al.   NATURE IMMUNOLOGY

Human Fc Receptor-Like 5 Binds Intact IgG via Mechanisms Distinct from Those of Fc Receptors

(2013) A. Franco et al.   JOURNAL OF IMMUNOLOGY

FCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signaling

(2013) Z. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Physical Interaction Between the Adaptor Proteins DOK3 and DAP12 Is Required to Inhibit Lipopolysaccharide Signaling in Macrophages

(2013) Q. Peng et al.   Science Signaling

IgG1 and IVIg induce inhibitory ITAM signaling through Fc RIII controlling inflammatory responses

(2012) M. Aloulou et al.   BLOOD

Intravenous Immunoglobulins Modulate Neutrophil Activation and Vascular Injury Through FcγRIII and SHP-1

(2012) Jung-Eun Jang et al.   CIRCULATION RESEARCH

Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production

(2012) Ivan Landego et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A pleckstrin homology-related domain in SHIP1 mediates membrane localization during Fcγ receptor-induced phagocytosis

(2012) Andrew Ming-Lum et al.   FASEB JOURNAL

Cutting Edge: Human FcRL4 and FcRL5 Are Receptors for IgA and IgG

(2012) T. J. Wilson et al.   JOURNAL OF IMMUNOLOGY

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

(2011) H. W. Sohn et al.   BLOOD

Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells

(2011) Konstantin Neumann et al.   CELLULAR SIGNALLING

Monophosphorylation of CD79a and CD79b ITAM Motifs Initiates a SHIP-1 Phosphatase-Mediated Inhibitory Signaling Cascade Required for B Cell Anergy

(2011) Shannon K. O'Neill et al.   IMMUNITY

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

Inhibitory ITAM Signaling Traps Activating Receptors with the Phosphatase SHP-1 to Form Polarized "Inhibisome" Clusters

(2011) S. Pfirsch-Maisonnas et al.   Science Signaling

CD23-mediated cell signaling in human B cells differs from signaling in cells of the monocytic lineage

(2010) Marcia A. Chan et al.   CLINICAL IMMUNOLOGY

TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1

(2010) Q. Peng et al.   Science Signaling

Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors

(2008) Carol T. Cady et al.   IMMUNOLOGICAL REVIEWS

Differential Dephosphorylation of the FcRγ Immunoreceptor Tyrosine-based Activation Motif Tyrosines with Dissimilar Potential for Activating Syk

(2008) Toshiyuki Yamashita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY