Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

Antibodies to watch in 2010

(2010) Janice M. Reichert   mAbs

Cleavage of IgGs by proteases associated with invasive diseases

(2010) Randall J. Brezski et al.   mAbs

Optimization of Fc-mediated effector functions of monoclonal antibodies

(2009) William R Strohl   CURRENT OPINION IN BIOTECHNOLOGY

Structure of the Murine Unglycosylated IgG1 Fc Fragment

(2009) Matthias J. Feige et al.   JOURNAL OF MOLECULAR BIOLOGY

Aglycosylated IgG variants expressed in bacteria that selectively bind Fc RI potentiate tumor cell killing by monocyte-dendritic cells

(2009) S. T. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fc-Disabled Anti-Mouse CD40L Antibodies Retain Efficacy in Promoting Transplantation Tolerance

(2008) S. R. Daley et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Specificity and affinity of human Fc  receptors and their polymorphic variants for human IgG subclasses

(2008) P. Bruhns et al.   BLOOD

When binding is enough: nonactivating antibody formats

(2008) Aran F Labrijn et al.   CURRENT OPINION IN IMMUNOLOGY

Molecular engineering and design of therapeutic antibodies

(2008) Leonard G Presta   CURRENT OPINION IN IMMUNOLOGY