Dynamics of Inter-heavy Chain Interactions in Human Immunoglobulin G (IgG) Subclasses Studied by Kinetic Fab Arm Exchange
出版年份 2014 全文链接
标题
Dynamics of Inter-heavy Chain Interactions in Human Immunoglobulin G (IgG) Subclasses Studied by Kinetic Fab Arm Exchange
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 9, Pages 6098-6109
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2014-01-15
DOI
10.1074/jbc.m113.541813
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nanomolar to sub-picomolar affinity measurements of antibody–antigen interactions and protein multimerizations: Fluorescence-assisted high-performance liquid chromatography
- (2013) Theo Rispens et al. ANALYTICAL BIOCHEMISTRY
- Engineering a Monomeric Fc Domain Modality byN-Glycosylation for the Half-life Extension of Biotherapeutics
- (2013) Tetsuya Ishino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Determinants of Unique Properties of Human IgG4-Fc
- (2013) Anna M. Davies et al. JOURNAL OF MOLECULAR BIOLOGY
- Drug interference in immunogenicity assays depends on valency
- (2013) Theo Rispens et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Mechanical Stability of the Antibody Domain CH3 Homodimer in Different Oxidation States
- (2013) Morten Bertz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies
- (2013) Xiaojie Yu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Monovalent IgG4 molecules
- (2013) Ian C. Wilkinson et al. mAbs
- An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations
- (2013) Omid Vafa et al. METHODS
- IgG2 Fc structure and the dynamic features of the IgG CH2–CH3 interface
- (2013) Alexey Teplyakov et al. MOLECULAR IMMUNOLOGY
- Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange
- (2013) A. F. Labrijn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation
- (2012) Pauline A van Schouwenburg et al. ANNALS OF THE RHEUMATIC DISEASES
- Effect of zinc on human IgG1 and its FcγR interactions
- (2012) Sophie Sibéril et al. IMMUNOLOGY LETTERS
- Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions
- (2012) Kavitha Baruah et al. JOURNAL OF MOLECULAR BIOLOGY
- Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis
- (2012) Thomas A. Bowden et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Disulfide bond structures of IgG molecules
- (2012) Hongcheng Liu et al. mAbs
- Crystal structure of the human IgG4 CH3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange
- (2012) Anna M. Davies et al. MOLECULAR IMMUNOLOGY
- Fc–Fc interactions of human IgG4 require dissociation of heavy chains and are formed predominantly by the intra-chain hinge isomer
- (2012) Theo Rispens et al. MOLECULAR IMMUNOLOGY
- Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans
- (2011) Tsunehiro Mizushima et al. GENES TO CELLS
- Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3-CH3 Interaction Strength
- (2011) A. F. Labrijn et al. JOURNAL OF IMMUNOLOGY
- Development and validation of immunoassays to quantify the half-antibody exchange of an IgG4 antibody, natalizumab (Tysabri®) with endogenous IgG4
- (2011) Renée I. Shapiro et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Use of a Human Recombinant Immunoglobulin G1 CH3 Domain as a Probe for Detecting Alternatively Folded Human IgG in Intravenous Ig Products
- (2011) Theresa Guhr et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanism of Immunoglobulin G4 Fab-arm Exchange
- (2011) Theo Rispens et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rapid LC–MS screening for IgG Fc modifications and allelic variants in blood
- (2011) Andrew M. Goetze et al. MOLECULAR IMMUNOLOGY
- Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose
- (2011) C. Ferrara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
- (2011) Nigel M. Stapleton et al. Nature Communications
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Influence of pH on Heat-Induced Aggregation and Degradation of Therapeutic Monoclonal Antibodies
- (2010) Tomoyoshi Ishikawa et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Traces of pFc’ in IVIG interact with human IgG Fc domains and counteract aggregation
- (2010) Theo Rispens et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Human immunoglobulin allotypes
- (2010) Roy Jefferis et al. mAbs
- Conformational plasticity of RNA for target recognition as revealed by the 2.15 Å crystal structure of a human IgG–aptamer complex
- (2010) Yusuke Nomura et al. NUCLEIC ACIDS RESEARCH
- Impact of Molecular Processing in the Hinge Region of Therapeutic IgG4 Antibodies on Disposition Profiles in Cynomolgus Monkeys
- (2009) K. Stubenrauch et al. DRUG METABOLISM AND DISPOSITION
- Measuring the poise of thiol/disulfide couples in vivo
- (2009) Dean P. Jones et al. FREE RADICAL BIOLOGY AND MEDICINE
- Human IgG4 Binds to IgG4 and Conformationally Altered IgG1 via Fc-Fc Interactions
- (2009) T. Rispens et al. JOURNAL OF IMMUNOLOGY
- Structure of the Murine Unglycosylated IgG1 Fc Fragment
- (2009) Matthias J. Feige et al. JOURNAL OF MOLECULAR BIOLOGY
- Aggregation-Prone Motifs in Human Immunoglobulin G
- (2009) Naresh Chennamsetty et al. JOURNAL OF MOLECULAR BIOLOGY
- Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions
- (2009) Max Crispin et al. JOURNAL OF MOLECULAR BIOLOGY
- Comparison of the ability of wild type and stabilized human IgG4 to undergo Fab arm exchange with endogenous IgG4 in vitro and in vivo
- (2009) Kenneth B. Lewis et al. MOLECULAR IMMUNOLOGY
- Structural characterization of a human Fc fragment engineered for extended serum half-life
- (2009) Vaheh Oganesyan et al. MOLECULAR IMMUNOLOGY
- Therapeutic IgG4 antibodies engage in Fab-arm exchange with endogenous human IgG4 in vivo
- (2009) Aran F Labrijn et al. NATURE BIOTECHNOLOGY
- Structural characterization of a human Fc fragment engineered for lack of effector functions
- (2008) Vaheh Oganesyan et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities
- (2008) A. Natsume et al. CANCER RESEARCH
- New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2·1-Å resolution
- (2008) Petr Kolenko et al. IMMUNOLOGY
- Structural characterization of a mutated, ADCC-enhanced human Fc fragment
- (2008) Vaheh Oganesyan et al. MOLECULAR IMMUNOLOGY
- IMGT(R), the international ImMunoGeneTics information system(R)
- (2008) M.-P. Lefranc et al. NUCLEIC ACIDS RESEARCH
- TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved
- (2008) A. H. Keeble et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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