标题
The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer
作者
关键词
Breast cancer, Receptor tyrosine kinases, Targeted therapies, Drug resistance
出版物
CANCER AND METASTASIS REVIEWS
Volume 35, Issue 4, Pages 575-588
出版商
Springer Nature
发表日期
2016-12-02
DOI
10.1007/s10555-016-9649-6
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Prognostic value of ERBB4 expression in patients with triple negative breast cancer
- (2016) Ji-Yeon Kim et al. BMC CANCER
- Blocking c-Met–mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors
- (2016) Yi Du et al. NATURE MEDICINE
- Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F
- (2016) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
- (2016) Chia-Wei Li et al. Nature Communications
- Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein
- (2016) Dudi Warsito et al. Oncotarget
- Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
- (2015) Padmanee Sharma et al. CELL
- Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells
- (2015) Kaleigh Canfield et al. CELL CYCLE
- WNT receptors profile expression in mature blood cells and immature leukemic cells: RYK emerges as a hallmark receptor of acute leukemia
- (2015) Monserrat Alvarez-Zavala et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases
- (2015) Mei-Kuang Chen et al. FEBS Journal
- PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response
- (2015) Hsin-Wei Liao et al. JOURNAL OF CLINICAL INVESTIGATION
- Validating ROS1 Rearrangements As a Therapeutic Target in Non–Small-Cell Lung Cancer
- (2015) Benjamin Solomon JOURNAL OF CLINICAL ONCOLOGY
- Crizotinib Therapy for Advanced Lung Adenocarcinoma and a ROS1 Rearrangement: Results From the EUROS1 Cohort
- (2015) Julien Mazières et al. JOURNAL OF CLINICAL ONCOLOGY
- Minireview: Were the IGF Signaling Inhibitors All Bad?
- (2015) Heather Beckwith et al. MOLECULAR ENDOCRINOLOGY
- Activating ERBB4 mutations in non-small cell lung cancer
- (2015) K J Kurppa et al. ONCOGENE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK
- (2015) Phillip B. Murray et al. Science Signaling
- Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK
- (2015) Phillip B. Murray et al. Science Signaling
- ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics
- (2014) Carlos L. Arteaga et al. CANCER CELL
- Definition of PKC-α, CDK6, and MET as Therapeutic Targets in Triple-Negative Breast Cancer
- (2014) Yi-Hsin Hsu et al. CANCER RESEARCH
- Successes, toxicities and challenges in solid tumours
- (2014) Joel W. Neal et al. Nature Reviews Clinical Oncology
- Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer
- (2014) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer
- (2014) U. Thirumurthi et al. Science Signaling
- Receptor Tyrosine Kinases: Legacy of the First Two Decades
- (2014) J. Schlessinger Cold Spring Harbor Perspectives in Biology
- The landscape of kinase fusions in cancer
- (2014) Nicolas Stransky et al. Nature Communications
- Oncogenic ERBB3 Mutations in Human Cancers
- (2013) Bijay S. Jaiswal et al. CANCER CELL
- Combination of Antibody That Inhibits Ligand-Independent HER3 Dimerization and a p110 Inhibitor Potently Blocks PI3K Signaling and Growth of HER2+ Breast Cancers
- (2013) J. T. Garrett et al. CANCER RESEARCH
- Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: A new era begins
- (2013) J. Remon et al. CANCER TREATMENT REVIEWS
- Molecular Pathways: ROS1 Fusion Proteins in Cancer
- (2013) K. D. Davies et al. CLINICAL CANCER RESEARCH
- The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered
- (2013) Hui K. Gan et al. FEBS Journal
- MET is a potential target for use in combination therapy with EGFR inhibition in triple-negative/basal-like breast cancer
- (2013) Yu Jin Kim et al. INTERNATIONAL JOURNAL OF CANCER
- ErbB3 downregulation enhances luminal breast tumor response to antiestrogens
- (2013) Meghan M. Morrison et al. JOURNAL OF CLINICAL INVESTIGATION
- Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3
- (2013) Toni M. Brand et al. PLoS One
- Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis
- (2013) Sandra M. Saldana et al. PLoS One
- ROS1 Expression in Invasive Ductal Carcinoma of the Breast Related to Proliferation Activity
- (2013) Minseob Eom et al. YONSEI MEDICAL JOURNAL
- Receptor Tyrosine Kinases in the Nucleus
- (2013) G. Carpenter et al. Cold Spring Harbor Perspectives in Biology
- A Mechanism for the Upregulation of EGF Receptor Levels in Glioblastomas
- (2013) Jingwen Zhang et al. Cell Reports
- Presence of anaplastic lymphoma kinase in inflammatory breast cancer
- (2013) Fredika M Robertson et al. SpringerPlus
- ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response
- (2012) Basak Icli et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
- (2012) Roxana Schillaci et al. BMC CANCER
- Role of epidermal growth factor receptor in breast cancer
- (2012) Hiroko Masuda et al. BREAST CANCER RESEARCH AND TREATMENT
- Increased MET and HGF gene copy numbers are associated with trastuzumab failure in HER2-positive metastatic breast cancer
- (2012) G Minuti et al. BRITISH JOURNAL OF CANCER
- Landscape of EGFR signaling network in human cancers: Biology and therapeutic response in relation to receptor subcellular locations
- (2012) Woody Han et al. CANCER LETTERS
- Epidermal Growth Factor Receptor Variant III Contributes to Cancer Stem Cell Phenotypes in Invasive Breast Carcinoma
- (2012) C. A. Del Vecchio et al. CANCER RESEARCH
- ErbB380kDa, a nuclear variant of the ErbB3 receptor, binds to the Cyclin D1 promoter to activate cell proliferation but is negatively controlled by p14ARF
- (2012) Laëtitia Andrique et al. CELLULAR SIGNALLING
- Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF
- (2012) Dudi Warsito et al. EMBO REPORTS
- HER3 Overexpression and Survival in Solid Tumors: A Meta-analysis
- (2012) Alberto Ocana et al. JNCI-Journal of the National Cancer Institute
- Cetuximab-mediated Tumor Regression Depends on Innate and Adaptive Immune Responses
- (2012) Xuanming Yang et al. MOLECULAR THERAPY
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Activating HER2 Mutations in HER2 Gene Amplification Negative Breast Cancer
- (2012) Ron Bose et al. Cancer Discovery
- Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family
- (2012) Ying-Nai Wang et al. Cell and Bioscience
- The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development
- (2011) J. Zhong et al. DEVELOPMENT
- Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells
- (2011) Wei-Chien Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gefitinib resistance in HCC mahlavu cells: Upregulation of CD133 expression, activation of IGF-1R signaling pathway, and enhancement of IGF-1R nuclear translocation
- (2011) Adam S. Bodzin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Anaplastic lymphoma kinase in human cancer
- (2011) Antonella Barreca et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
- (2011) Siyuan Zhang et al. NATURE MEDICINE
- Feedback regulation of EGFR signalling: decision making by early and delayed loops
- (2011) Roi Avraham et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Elevated BCRP/ABCG2 Expression Confers Acquired Resistance to Gefitinib in Wild-Type EGFR-Expressing Cells
- (2011) Yun-Ju Chen et al. PLoS One
- A Perspective on Cancer Cell Metastasis
- (2011) C. L. Chaffer et al. SCIENCE
- HER-3 Overexpression Is Prognostic of Reduced Breast Cancer Survival
- (2010) Connie G. Chiu et al. ANNALS OF SURGERY
- Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells
- (2010) T. Aleksic et al. CANCER RESEARCH
- Cell Signaling by Receptor Tyrosine Kinases
- (2010) Mark A. Lemmon et al. CELL
- Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654
- (2010) Klaus Dittmann et al. FEBS LETTERS
- Breast Cancer Subtypes and the Risk of Local and Regional Relapse
- (2010) K. David Voduc et al. JOURNAL OF CLINICAL ONCOLOGY
- Nuclear EGFR in ductal invasive breast cancer: correlation with cyclin-D1 and prognosis
- (2010) Ita Hadžisejdić et al. MODERN PATHOLOGY
- Progesterone Receptor Induces ErbB-2 Nuclear Translocation To Promote Breast Cancer Growth via a Novel Transcriptional Effect: ErbB-2 Function as a Coactivator of Stat3
- (2010) W. Beguelin et al. MOLECULAR AND CELLULAR BIOLOGY
- Diverse somatic mutation patterns and pathway alterations in human cancers
- (2010) Zhengyan Kan et al. NATURE
- Understanding resistance to EGFR inhibitors—impact on future treatment strategies
- (2010) Deric L. Wheeler et al. Nature Reviews Clinical Oncology
- MET signalling: principles and functions in development, organ regeneration and cancer
- (2010) Livio Trusolino et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors
- (2010) Young Lim Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- EGFR Signaling and Drug Discovery
- (2010) Georg Lurje et al. ONCOLOGY
- ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation
- (2010) Fumin Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus
- (2010) L. Huo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevation of Receptor Tyrosine Kinase EphA2 Mediates Resistance to Trastuzumab Therapy
- (2009) G. Zhuang et al. CANCER RESEARCH
- Nuclear localization of active HGF receptor Met in aggressive MDA-MB231 breast carcinoma cells
- (2009) E. Matteucci et al. CARCINOGENESIS
- Nuclear Translocation of the Epidermal Growth Factor Receptor Family Membrane Tyrosine Kinase Receptors
- (2009) S.-C. Wang et al. CLINICAL CANCER RESEARCH
- ErbB receptors and signaling pathways in cancer
- (2009) Nancy E Hynes et al. CURRENT OPINION IN CELL BIOLOGY
- Cdc37 Regulates Ryk Signaling by Stabilizing the Cleaved Ryk Intracellular Domain
- (2009) Jungmook Lyu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exon Array Profiling Detects EML4-ALK Fusion in Breast, Colorectal, and Non-Small Cell Lung Cancers
- (2009) E. Lin et al. MOLECULAR CANCER RESEARCH
- Linear combinations of docking affinities explain quantitative differences in RTK signaling
- (2009) Andrew Gordus et al. Molecular Systems Biology
- Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4
- (2009) Todd D Prickett et al. NATURE GENETICS
- Predictive value of EGFR and HER2 overexpression in advanced non-small-cell lung cancer
- (2009) F R Hirsch et al. ONCOGENE
- Crosstalk in Met receptor oncogenesis
- (2009) Andrea Z. Lai et al. TRENDS IN CELL BIOLOGY
- Correlates and Determinants of Nuclear Epidermal Growth Factor Receptor Content in an Oropharyngeal Cancer Tissue Microarray
- (2008) A. Psyrri et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- The HER4/4ICD Estrogen Receptor Coactivator and BH3-Only Protein Is an Effector of Tamoxifen-Induced Apoptosis
- (2008) A. Naresh et al. CANCER RESEARCH
- A Central Role for HER3 in HER2-Amplified Breast Cancer: Implications for Targeted Therapy
- (2008) S. T. Lee-Hoeflich et al. CANCER RESEARCH
- Met Receptor Contributes to Trastuzumab Resistance of Her2-Overexpressing Breast Cancer Cells
- (2008) D. L. Shattuck et al. CANCER RESEARCH
- Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate
- (2008) G. D. Lewis Phillips et al. CANCER RESEARCH
- Cleavage of the Wnt Receptor Ryk Regulates Neuronal Differentiation during Cortical Neurogenesis
- (2008) Jungmook Lyu et al. DEVELOPMENTAL CELL
- The status and role of ErbB receptors in human cancer
- (2008) I. Überall et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- EGFR family: Structure physiology signalling and therapeutic targets†
- (2008) Antony W. Burgess GROWTH FACTORS
- The epidermal growth factor receptor ligands at a glance
- (2008) Marlon R. Schneider et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors
- (2008) Antonello Mai et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer
- (2008) Weiya Xia et al. MOLECULAR CARCINOGENESIS
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression
- (2008) Liang-Yi Hung et al. NUCLEIC ACIDS RESEARCH
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