Gefitinib resistance in HCC mahlavu cells: Upregulation of CD133 expression, activation of IGF-1R signaling pathway, and enhancement of IGF-1R nuclear translocation

Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9

(2010) Hua Deng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CD133 expression in chemo-resistant Ewing sarcoma cells

(2010) Xiaohua Jiang et al.   BMC CANCER

Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells

(2010) T. Aleksic et al.   CANCER RESEARCH

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

CD133 expression is a potential prognostic indicator in intrahepatic cholangiocarcinoma

(2010) Mitsuo Shimada et al.   JOURNAL OF GASTROENTEROLOGY

CD133 suppresses neuroblastoma cell differentiation via signal pathway modification

(2010) H Takenobu et al.   ONCOGENE

SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

(2010) B. Sehat et al.   Science Signaling

Insulin-Like Growth Factor-1 Receptor Inhibition Induces a Resistance Mechanism via the Epidermal Growth Factor Receptor/HER3/AKT Signaling Pathway: Rational Basis for Cotargeting Insulin-Like Growth Factor-1 Receptor and Epidermal Growth Factor Receptor in Hepatocellular Carcinoma

(2009) C. Desbois-Mouthon et al.   CLINICAL CANCER RESEARCH

Resistance mechanisms to cancer chemotherapy

(2008) Kelly Marie Redmond   Frontiers in Bioscience-Landmark

Insulin, the Insulin-Like Growth Factor Axis, and Mortality in Patients With Nonmetastatic Colorectal Cancer

(2008) Brian M. Wolpin et al.   JOURNAL OF CLINICAL ONCOLOGY