Feedback regulation of EGFR signalling: decision making by early and delayed loops

Expression of leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins in human ependymoma relates to tumor location, WHO Grade, and patient age

(2011) W. Yi et al.   CLINICAL NEUROPATHOLOGY

An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

(2010) Qing Sheng et al.   CANCER CELL

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

PTPD1 Supports Receptor Stability and Mitogenic Signaling in Bladder Cancer Cells

(2010) Annalisa Carlucci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTP1B Targets the Endosomal Sorting Machinery

(2010) Matthew Stuible et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation

(2010) Yuri Frosi et al.   JOURNAL OF CELL BIOLOGY

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

(2010) Lai Kuan Goh et al.   JOURNAL OF CELL BIOLOGY

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased accuracy of ligand sensing by receptor internalization

(2010) Gerardo Aquino et al.   PHYSICAL REVIEW E

Mig-6 controls EGFR trafficking and suppresses gliomagenesis

(2010) H. Ying et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breakdown of endocytosis in the oncogenic activation of receptor tyrosine kinases

(2009) Jasmine V. Abella et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

EMT, the cytoskeleton, and cancer cell invasion

(2009) Mahmut Yilmaz et al.   CANCER AND METASTASIS REVIEWS

Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation

(2009) Diana C. Hargreaves et al.   CELL

Defining Network Topologies that Can Achieve Biochemical Adaptation

(2009) Wenzhe Ma et al.   CELL

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

A Unifying Model for the Selective Regulation of Inducible Transcription by CpG Islands and Nucleosome Remodeling

(2009) Vladimir R. Ramirez-Carrozzi et al.   CELL

An Unbiased Screen Identifies DEP-1 Tumor Suppressor as a Phosphatase Controlling EGFR Endocytosis

(2009) Gabi Tarcic et al.   CURRENT BIOLOGY

Tyrosine phosphorylation: thirty years and counting

(2009) Tony Hunter   CURRENT OPINION IN CELL BIOLOGY

A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts

(2009) Nils Blüthgen et al.   FEBS Journal

Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway

(2009) S.-Y. Shin et al.   JOURNAL OF CELL SCIENCE

Dynamics and Variability of ERK2 Response to EGF in Individual Living Cells

(2009) Cellina Cohen-Saidon et al.   MOLECULAR CELL

Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling

(2009) Lea Goentoro et al.   MOLECULAR CELL

Ras/MAPK signaling from endomembranes

(2009) Nicole Fehrenbacher et al.   Molecular Oncology

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

(2009) Harish Shankaran et al.   Molecular Systems Biology

Cell fate decisions are specified by the dynamic ERK interactome

(2009) Alex von Kriegsheim et al.   NATURE CELL BIOLOGY

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4

(2009) Todd D Prickett et al.   NATURE GENETICS

Regulation of endocytosis via the oxygen-sensing pathway

(2009) Yi Wang et al.   NATURE MEDICINE

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

Regulation of Epidermal Growth Factor Receptor Trafficking by Lysine Deacetylase HDAC6

(2009) Y. Lissanu Deribe et al.   Science Signaling

Differential Effects of EGFR Ligands on Endocytic Sorting of the Receptor

(2009) Kirstine Roepstorff et al.   TRAFFIC

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Negative elongation factor NELF controls transcription of immediate early genes in a stimulus-specific manner

(2008) Toshitsugu Fujita et al.   EXPERIMENTAL CELL RESEARCH

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

(2008) Tim F Cloughesy et al.   PLOS MEDICINE