标题
Mitochondria as Potential Targets in Alzheimer Disease Therapy: An Update
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-08-23
DOI
10.3389/fphar.2019.00902
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mitochondrial proteins: from biogenesis to functional networks
- (2019) Nikolaus Pfanner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
- (2019) D. Allan Butterfield et al. NATURE REVIEWS NEUROSCIENCE
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Reverting Metabolic Dysfunction in Cortex and Cerebellum of APP/PS1 Mice, a Model for Alzheimer’s Disease by Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Agonist
- (2019) Kai Lun Chang et al. MOLECULAR NEUROBIOLOGY
- The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms
- (2018) Inhae Kang et al. FEBS LETTERS
- Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer’s Disease
- (2018) P. Hemachandra Reddy et al. JOURNAL OF ALZHEIMERS DISEASE
- Physical Exercise During Pregnancy Prevents Cognitive Impairment Induced by Amyloid-β in Adult Offspring Rats
- (2018) Caroline Peres Klein et al. MOLECULAR NEUROBIOLOGY
- Benefit of Oleuropein Aglycone for Alzheimer’s Disease by Promoting Autophagy
- (2018) Joaquín G. Cordero et al. Oxidative Medicine and Cellular Longevity
- The effects of exercise on hypothalamic neurodegeneration of Alzheimer’s disease mouse model
- (2018) Khoa Do et al. PLoS One
- Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients
- (2018) Julian H. Birnbaum et al. Stem Cell Research
- Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer’s disease
- (2018) Hui Wang et al. TOXICOLOGY LETTERS
- A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease
- (2018) Estela Area-Gomez et al. Cell Death & Disease
- 13 reasons why the brain is susceptible to oxidative stress
- (2018) James Nathan Cobley et al. Redox Biology
- Green Tea Epigallocatechin-3-Gallate (EGCG) and Other Flavonoids Reduce Alzheimer's Amyloid-Induced Mitochondrial Dysfunction
- (2018) Natasa Dragicevic et al. JOURNAL OF ALZHEIMERS DISEASE
- Coenzyme Q10 Decreases Amyloid Pathology and Improves Behavior in a Transgenic Mouse Model of Alzheimer's Disease
- (2018) Magali Dumont et al. JOURNAL OF ALZHEIMERS DISEASE
- Behavioral Improvement after Chronic Administration of Coenzyme Q10 in P301S Transgenic Mice
- (2018) Ceyhan Elipenahli et al. JOURNAL OF ALZHEIMERS DISEASE
- Dimebon Ameliorates Amyloid-β Induced Impairments of Mitochondrial Form and Function
- (2018) Schamim H. Eckert et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuroprotective Role of Trans-Resveratrol in a Murine Model of Familial Alzheimer's Disease
- (2018) David Porquet et al. JOURNAL OF ALZHEIMERS DISEASE
- Phenylpropanoids and Alzheimer's disease: A potential therapeutic platform
- (2018) Igri Kolaj et al. NEUROCHEMISTRY INTERNATIONAL
- Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer’s Disease
- (2018) Schamim H Eckert et al. Aging and Disease
- Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer’s disease
- (2018) Gary P. Morris et al. ACTA NEUROPATHOLOGICA
- Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative
- (2018) Dallas P. Veitch et al. Alzheimers & Dementia
- Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection
- (2018) Antonella Tramutola et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial biogenesis mediated by melatonin in an APPswe/PS1dE9 transgenic mice model
- (2018) ChaoYuan Song et al. NEUROREPORT
- Associations of the Mediterranean diet with cognitive and neuroimaging phenotypes of dementia in healthy older adults
- (2018) Aimee J Karstens et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Protective Effects of Wogonin against Alzheimer’s Disease by Inhibition of Amyloidogenic Pathway
- (2017) Ding-Siang Huang et al. Evidence-based Complementary and Alternative Medicine
- Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
- (2017) Shilpy Dixit et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer’s disease
- (2017) P. Hemachandra Reddy et al. HUMAN MOLECULAR GENETICS
- Inhibition of mitochondrial fragmentation protects against Alzheimer’s disease in rodent model
- (2017) Wenzhang Wang et al. HUMAN MOLECULAR GENETICS
- Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer’s Disease
- (2017) Qian Cai et al. JOURNAL OF ALZHEIMERS DISEASE
- Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease
- (2017) Robert J. Pawlosky et al. JOURNAL OF NEUROCHEMISTRY
- Novel ketone body therapy for managing Alzheimer's disease
- (2017) Michelle A. Puchowicz et al. JOURNAL OF NEUROCHEMISTRY
- Potential oxidative stress biomarkers of mild cognitive impairment due to Alzheimer disease
- (2017) Ana García-Blanco et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Dementia prevention, intervention, and care
- (2017) Gill Livingston et al. LANCET
- Short-Term Fructose Feeding Induces Inflammation and Oxidative Stress in the Hippocampus of Young and Adult Rats
- (2017) Luisa Cigliano et al. MOLECULAR NEUROBIOLOGY
- Olive (Olea europaea L.) Biophenols: A Nutriceutical against Oxidative Stress in SH-SY5Y Cells
- (2017) Syed Omar et al. MOLECULES
- Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy
- (2017) Timothy M. Brenza et al. Nanomedicine-Nanotechnology Biology and Medicine
- Multifactorial causal model of brain (dis)organization and therapeutic intervention: Application to Alzheimer’s disease
- (2017) Yasser Iturria-Medina et al. NEUROIMAGE
- (R)-α-Lipoyl-Gly- l -Pro- l -Glu dimethyl ester as dual acting agent for the treatment of Alzheimer's disease
- (2017) Lisa Marinelli et al. NEUROPEPTIDES
- Curcumin in Alzheimer’s disease: Can we think to new strategies and perspectives for this molecule?
- (2017) Melania Maria Serafini et al. PHARMACOLOGICAL RESEARCH
- Association between Mitofusin 2 Gene Polymorphisms and Late-Onset Alzheimer's Disease in the Korean Population
- (2017) Young Jong Kim et al. Psychiatry Investigation
- Caloric restriction improves health and survival of rhesus monkeys
- (2017) Julie A. Mattison et al. Nature Communications
- Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
- (2017) Anna Ochalek et al. Alzheimers Research & Therapy
- Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer’s Disease by Vitamin E and Selenium Trial (PREADViSE)
- (2017) Richard J. Kryscio et al. JAMA Neurology
- PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease
- (2017) Minna Oksanen et al. Stem Cell Reports
- A Mitocentric View of Alzheimer's Disease Suggests Multi-Faceted Treatments
- (2017) Gary E. Gibson et al. JOURNAL OF ALZHEIMERS DISEASE
- Aerobic Exercise Improves Cognition for Older Adults with Glucose Intolerance, A Risk Factor for Alzheimer's Disease
- (2017) Laura D. Baker et al. JOURNAL OF ALZHEIMERS DISEASE
- Dimebon (Latrepirdine) Enhances Mitochondrial Function and Protects Neuronal Cells from Death
- (2017) Shouting Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons
- (2017) Maria Manczak et al. JOURNAL OF ALZHEIMERS DISEASE
- An antioxidant specifically targeting mitochondria delays progression of Alzheimer’s disease-like pathology
- (2016) Natalia Stefanova et al. Aging-US
- Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death
- (2016) Xiaonan Wang et al. BRAIN RESEARCH
- Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology
- (2016) Daniela Pantano et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Mitochondrial quality control by the Pink1/Parkin system
- (2016) Cornelia Rüb et al. CELL AND TISSUE RESEARCH
- N -acetylcysteine protects memory decline induced by streptozotocin in mice
- (2016) Michael Costa et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Can Diet and Physical Activity Limit Alzheimer's Disease Risk?
- (2016) Shraddha Rege et al. Current Alzheimer Research
- Maintenance of Cognitive Performance and Mood for Individuals with Alzheimer’s Disease Following Consumption of a Nutraceutical Formulation: A One-Year, Open-Label Study
- (2016) Ruth Remington et al. JOURNAL OF ALZHEIMERS DISEASE
- ER–Mitochondria contact sites: A new regulator of cellular calcium flux comes into play
- (2016) Michiel Krols et al. JOURNAL OF CELL BIOLOGY
- Metabolic regulation of mitochondrial dynamics
- (2016) Prashant Mishra et al. JOURNAL OF CELL BIOLOGY
- Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease
- (2016) P Hemachandra Reddy et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process
- (2016) Giovanna Cenini et al. MOLECULAR BIOLOGY OF THE CELL
- Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria
- (2016) Juan A. Godoy et al. MOLECULAR NEUROBIOLOGY
- The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels
- (2016) Hasan Balaban et al. MOLECULAR NEUROBIOLOGY
- Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice
- (2016) Yunhua Peng et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
- (2016) Dongryeol Ryu et al. NATURE MEDICINE
- A TOMM40 poly-T variant modulates gene expression and is associated with vocabulary ability and decline in nonpathologic aging
- (2016) A. Payton et al. NEUROBIOLOGY OF AGING
- Epigallocatechin Gallate Attenuates β-Amyloid Generation and Oxidative Stress Involvement of PPARγ in N2a/APP695 Cells
- (2016) Zhao-Xu Zhang et al. NEUROCHEMICAL RESEARCH
- Resveratrol Attenuates Aβ25–35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway
- (2016) Haoyue Deng et al. NEUROCHEMICAL RESEARCH
- IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses
- (2016) Neta Gazit et al. NEURON
- Quercetin attenuates neuronal death against aluminum-induced neurodegeneration in the rat hippocampus
- (2016) D.R. Sharma et al. NEUROSCIENCE
- Moderate activation of autophagy regulates the intracellular calcium ion concentration and mitochondrial membrane potential in beta-amyloid-treated PC12 cells
- (2016) Zhongfeng Xue et al. NEUROSCIENCE LETTERS
- Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease
- (2016) Simon J. Beck et al. Nature Communications
- Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2
- (2016) Riccardo Filadi et al. Cell Reports
- Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers
- (2016) Pedro Lobos et al. NEURAL PLASTICITY
- Quercetin Protects against Okadaic Acid-Induced Injury via MAPK and PI3K/Akt/GSK3β Signaling Pathways in HT22 Hippocampal Neurons
- (2016) Wei Jiang et al. PLoS One
- Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 Mouse Model
- (2015) Gorka Gerenu et al. ACS Chemical Neuroscience
- Influence of antioxidant SkQ1 on accumulation of mitochondrial DNA deletions in the hippocampus of senescence-accelerated OXYS rats
- (2015) P. S. Loshchenova et al. BIOCHEMISTRY-MOSCOW
- Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer’s disease-relevant murine model
- (2015) Aaron N Long et al. BMC Neurology
- What Are the Benefits of Exercise for Alzheimer’s Disease? A Systematic Review of the Past 10 Years
- (2015) Salma S.S. Hernández et al. JOURNAL OF AGING AND PHYSICAL ACTIVITY
- Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review
- (2015) Thierry Paillard et al. Journal of Clinical Neurology
- Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35-induced neurotoxicity in human neuroblastoma cells
- (2015) Navrattan Kaur et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity
- (2015) Vedad Delic et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Dietary Tocotrienol/γ-Cyclodextrin Complex Increases Mitochondrial Membrane Potential and ATP Concentrations in the Brains of Aged Mice
- (2015) Anke Schloesser et al. Oxidative Medicine and Cellular Longevity
- The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid β peptide 42/40 ratio in healthy elderly persons: a randomized controlled trial
- (2015) Hisayo Yokoyama et al. BMC Geriatrics
- The neuroprotective effects of tocotrienol rich fraction and alpha tocopherol against glutamate injury in astrocytes
- (2015) Thilaga Rati Selvaraju et al. Bosnian Journal of Basic Medical Sciences
- Curcumin-Protected PC12 Cells Against Glutamate-Induced Oxidative Toxicity
- (2015) Chi-Huang Chang et al. FOOD TECHNOLOGY AND BIOTECHNOLOGY
- Dose-Response of Aerobic Exercise on Cognition: A Community-Based, Pilot Randomized Controlled Trial
- (2015) Eric D. Vidoni et al. PLoS One
- The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes
- (2014) Colton Linnertz et al. Alzheimers & Dementia
- Mitochondrial Biogenesis in Health and Disease. Molecular and Therapeutic Approaches
- (2014) Fabian Sanchis-Gomar et al. CURRENT PHARMACEUTICAL DESIGN
- The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
- (2014) Li Fang Ng et al. FREE RADICAL BIOLOGY AND MEDICINE
- Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis
- (2014) Heather M. Wilkins et al. HUMAN MOLECULAR GENETICS
- Effects of Long-Term Treatment with Quercetin on Cognition and Mitochondrial Function in a Mouse Model of Alzheimer’s Disease
- (2014) Dong-Mei Wang et al. NEUROCHEMICAL RESEARCH
- Lysosomal alkalization and dysfunction in human fibroblasts with the Alzheimer’s disease-linked presenilin 1 A246E mutation can be reversed with cAMP
- (2014) E.E. Coffey et al. NEUROSCIENCE
- Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?
- (2014) Torbjörn Persson et al. Oxidative Medicine and Cellular Longevity
- Exercise-Induced Neuroprotection of Hippocampus in APP/PS1 Transgenic Mice via Upregulation of Mitochondrial 8-Oxoguanine DNA Glycosylase
- (2014) Hai Bo et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial-Targeted Curcuminoids: A Strategy to Enhance Bioavailability and Anticancer Efficacy of Curcumin
- (2014) Cheruku Apoorva Reddy et al. PLoS One
- Coenzyme Q10 Protects Human Endothelial Cells from β-Amyloid Uptake and Oxidative Stress-Induced Injury
- (2014) Mario Durán-Prado et al. PLoS One
- High-dose of vitamin C supplementation reduces amyloid plaque burden and ameliorates pathological changes in the brain of 5XFAD mice
- (2014) S-Y Kook et al. Cell Death & Disease
- Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome
- (2013) Daniela Valenti et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- March separate, strike together — Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease
- (2013) Anne Eckert et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives
- (2013) Russell H. Swerdlow et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell
- (2013) Xueqi Gan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Effect of DHA and CoenzymeQ10 Against A�- and Zinc-Induced Mitochondrial Dysfunction in Human Neuronal Cells
- (2013) Nadia Sadli et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Different Forms of Selenoprotein M Differentially Affect Aβ Aggregation and ROS Generation
- (2013) Ping Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Age-Dependent Modulation of Synaptic Plasticity and Insulin Mimetic Effect of Lipoic Acid on a Mouse Model of Alzheimer’s Disease
- (2013) Harsh Sancheti et al. PLoS One
- The Polyphenol Oleuropein Aglycone Protects TgCRND8 Mice against Aß Plaque Pathology
- (2013) Cristina Grossi et al. PLoS One
- Selenium neurotoxicity in humans: Bridging laboratory and epidemiologic studies
- (2013) Marco Vinceti et al. TOXICOLOGY LETTERS
- Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability
- (2013) P Weisová et al. Translational Psychiatry
- Sites of reactive oxygen species generation by mitochondria oxidizing different substrates
- (2013) Casey L. Quinlan et al. Redox Biology
- Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding
- (2012) Anna Picca et al. AGE
- Antioxidants for Alzheimer Disease
- (2012) Douglas R. Galasko et al. ARCHIVES OF NEUROLOGY
- The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25?35-induced oxidative stress and neuronal apoptosis in rats
- (2012) XiaoQiang Tian et al. BEHAVIOURAL BRAIN RESEARCH
- Green tea (−)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia
- (2012) Regina Biasibetti et al. BEHAVIOURAL BRAIN RESEARCH
- Chaperone–protease networks in mitochondrial protein homeostasis
- (2012) Wolfgang Voos BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Scutellaria baicalensisExtracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction
- (2012) A-Rang Im et al. Evidence-based Complementary and Alternative Medicine
- Mitochondria-targeted catalase reduces abnormal APP processing, amyloid production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension
- (2012) P. Mao et al. HUMAN MOLECULAR GENETICS
- Long-term use of standardised ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial
- (2012) Bruno Vellas et al. LANCET NEUROLOGY
- A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing
- (2012) G Davies et al. MOLECULAR PSYCHIATRY
- Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration
- (2012) Zu-Hang Sheng et al. NATURE REVIEWS NEUROSCIENCE
- A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
- (2012) Yoshihiro Kashiwaya et al. NEUROBIOLOGY OF AGING
- Effect of One-Year Vitamin C- and E-Supplementation on Cerebrospinal Fluid Oxidation Parameters and Clinical Course in Alzheimer’s Disease
- (2012) Sönke Arlt et al. NEUROCHEMICAL RESEARCH
- Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo
- (2012) Brian DuBoff et al. NEURON
- Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells
- (2012) Natasa Dragicevic et al. NEUROPHARMACOLOGY
- Accumulation of Exogenous Amyloid-BetaPeptide in Hippocampal Mitochondria Causes Their Dysfunction: A Protective Role for Melatonin
- (2012) Sergio Rosales-Corral et al. Oxidative Medicine and Cellular Longevity
- Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study
- (2012) John M Ringman et al. Alzheimers Research & Therapy
- The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype
- (2011) Sterling C. Johnson et al. Alzheimers & Dementia
- Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
- (2011) Marcus J. Calkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
- (2011) Maria Manczak et al. HUMAN MOLECULAR GENETICS
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
- (2011) Eugenia Morselli et al. JOURNAL OF CELL BIOLOGY
- Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease
- (2011) Baiyang Sheng et al. JOURNAL OF NEUROCHEMISTRY
- The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
- (2011) M. J. McManus et al. JOURNAL OF NEUROSCIENCE
- Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signaling
- (2011) Natasa Dragicevic et al. JOURNAL OF PINEAL RESEARCH
- mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca2+, and lipid insults in NARP cybrids: a potential therapeutic target for melatonin
- (2011) Tsung-I Peng et al. JOURNAL OF PINEAL RESEARCH
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Curcumin Attenuates Aluminum-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain
- (2011) Pooja Khanna Sood et al. NEUROTOXICITY RESEARCH
- 2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease
- (2011) Jia Yao et al. PLoS One
- Exercise training increases size of hippocampus and improves memory
- (2011) K. I. Erickson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Short-term fasting induces profound neuronal autophagy
- (2010) Mehrdad Alirezaei et al. Autophagy
- Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
- (2010) Richard C. Scarpulla BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- Melatonin Reduces Apoptosis Induced by Calcium Signaling in Human Leukocytes: Evidence for the Involvement of Mitochondria and Bax Activation
- (2010) Javier Espino et al. JOURNAL OF MEMBRANE BIOLOGY
- Expression of -Amyloid Induced Age-Dependent Presynaptic and Axonal Changes in Drosophila
- (2010) X.-L. Zhao et al. JOURNAL OF NEUROSCIENCE
- Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: Toward therapeutic modulation of mild cognitive impairment
- (2010) Quanzhen Huang et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease
- (2010) Dimitrios Kapogiannis et al. LANCET NEUROLOGY
- Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo
- (2010) Anne Eckert et al. MOLECULAR NEUROBIOLOGY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Genome-wide association study of CSF biomarkers A 1-42, t-tau, and p-tau181p in the ADNI cohort
- (2010) S. Kim et al. NEUROLOGY
- Dimebon Inhibits Calcium-Induced Swelling of Rat Brain Mitochondria But Does Not Alter Calcium Retention or Cytochrome C Release
- (2010) Kranthi Kumari Naga et al. NEUROMOLECULAR MEDICINE
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- Ginkgo Biloba Extract Ameliorates Oxidative Phosphorylation Performance and Rescues Aβ-Induced Failure
- (2010) Virginie Rhein et al. PLoS One
- Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
- (2010) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance
- (2009) J. Mark Davis et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia
- (2009) Weiping Qin et al. ARCHIVES OF NEUROLOGY
- Importing Mitochondrial Proteins: Machineries and Mechanisms
- (2009) Agnieszka Chacinska et al. CELL
- Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release
- (2009) Giuseppe Petrosillo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese
- (2009) Norihiro Takei et al. GENOMICS
- Ginkgo biloba for Preventing Cognitive Decline in Older AdultsA Randomized Trial
- (2009) Beth E. Snitz JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease
- (2009) Larry Baum et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- Drosophila Miro Is Required for Both Anterograde and Retrograde Axonal Mitochondrial Transport
- (2009) G. J. Russo et al. JOURNAL OF NEUROSCIENCE
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Differential effects of melatonin on amyloid-β peptide 25-35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture
- (2009) Weiguo Dong et al. JOURNAL OF PINEAL RESEARCH
- A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
- (2009) A D Roses et al. PHARMACOGENOMICS JOURNAL
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
- (2009) Dong-Hyung Cho et al. SCIENCE
- Dynamin-Like Protein 1 Reduction Underlies Mitochondrial Morphology and Distribution Abnormalities in Fibroblasts from Sporadic Alzheimer's Disease Patients
- (2008) Xinglong Wang et al. AMERICAN JOURNAL OF PATHOLOGY
- Green Tea Epigallocatechin 3-Gallate Accumulates in Mitochondria and Displays a Selective Antiapoptotic Effect Against Inducers of Mitochondrial Oxidative Stress in Neurons
- (2008) Emily K. Schroeder et al. ANTIOXIDANTS & REDOX SIGNALING
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Protective effect of quercetin in primary neurons against Aβ(1–42): relevance to Alzheimer's disease
- (2008) Mubeen Ahmad Ansari et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study
- (2008) Rachelle S Doody et al. LANCET
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
- (2008) S. Hauptmann et al. NEUROBIOLOGY OF AGING
- Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease
- (2008) Tanea Reed et al. NEUROBIOLOGY OF DISEASE
- Amyloid- overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
- (2008) X. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The amyloid -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
- (2008) C. A. Hansson Petersen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: Neurofilaments attenuate tau-mediated neurite instability
- (2007) Maya Dubey et al. CELL MOTILITY AND THE CYTOSKELETON
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More