The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms
出版年份 2019 全文链接
标题
The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 99, Issue 2, Pages 1153-1222
出版商
American Physiological Society
发表日期
2019-02-06
DOI
10.1152/physrev.00058.2017
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- Role of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Imipramine, Clomipramine, and Trimipramine
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- Developmental hyperbilirubinemia and CNS toxicity in mice humanized with the UDP glucuronosyltransferase 1 (UGT1) locus
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- Organic Solute Transporter, OSTα-OSTβ: Its Role in Bile Acid Transport and Cholestasis
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- Src supports UDP-glucuronosyltransferase-2B7 detoxification of catechol estrogens associated with breast cancer
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- Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells
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- Effects of UGT1A1*28 polymorphism on raloxifene pharmacokinetics and pharmacodynamics
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- Evidence for oxazepam as anin vivoprobe of UGT2B15: oxazepam clearance is reduced byUGT2B15D85Y polymorphism but unaffected byUGT2B17deletion
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- Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancer
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- UGT1A1 polymorphism and hyperbilirubinemia in a patient who received sorafenib
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- Characterization of UGTs Active against SAHA and Association between SAHA Glucuronidation Activity Phenotype with UGT Genotype
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- TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
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- 4-Hydroxy-3-methoxymethamphetamine Glucuronide as a Phase II Metabolite of 3,4-Methylenedioxymethamphetamine: Enzyme-Assisted Synthesis and Involvement of Human Hepatic Uridine 5′-Diphosphate-Glucuronosyltransferase 2B15 in the Glucuronidation
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- Glucuronidation of Dihydrotestosterone and trans-Androsterone by Recombinant UDP-Glucuronosyltransferase (UGT) 1A4: Evidence for Multiple UGT1A4 Aglycone Binding Sites
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- Quantitative Analysis of UDP-Glucuronosyltransferase (UGT) 1A and UGT2B Expression Levels in Human Livers
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- Identification of Human UGT2B7 as the Major Isoform Involved in the O-Glucuronidation of Chloramphenicol
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- Sorafenib
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- Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10
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- UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans
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- Targeting bile-acid signalling for metabolic diseases
- (2008) Charles Thomas et al. NATURE REVIEWS DRUG DISCOVERY
- Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells
- (2008) M Asim et al. ONCOGENE
- Metabolism and Renal Elimination of Gaboxadol in Humans: Role of UDP-Glucuronosyltransferases and Transporters
- (2008) Xiao-Yan Chu et al. PHARMACEUTICAL RESEARCH
- Cost–effectiveness ofUGT1A1genotyping in second-line, high-dose, once every 3 weeks irinotecan monotherapy treatment of colorectal cancer
- (2008) Marko Obradovic et al. PHARMACOGENOMICS
- Stereoselective Glucuronidation of Propranolol in Human and Cynomolgus Monkey Liver Microsomes: Role of Human Hepatic UDP-Glucuronosyltransferase Isoforms, UGT1A9, UGT2B4 and UGT2B7
- (2008) Nobumitsu Hanioka et al. PHARMACOLOGY
- The organic solute transporter - , Ost -Ost , is essential for intestinal bile acid transport and homeostasis
- (2008) A. Rao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes
- (2008) Bo-Ying Bao et al. PROSTATE
- TheUGT2B17gene deletion is not associated with prostate cancer risk
- (2008) Mats Olsson et al. PROSTATE
- Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues
- (2008) Athena Starlard-Davenport et al. STEROIDS
- Genetic variability of aryl hydrocarbon receptor (AhR)-mediated regulation of the human UDP glucuronosyltransferase (UGT) 1A4 gene
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