标题
Toward biotherapeutic product real-time quality monitoring
作者
关键词
-
出版物
CRITICAL REVIEWS IN BIOTECHNOLOGY
Volume 39, Issue 3, Pages 289-305
出版商
Informa UK Limited
发表日期
2019-02-06
DOI
10.1080/07388551.2018.1524362
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sequential Multivariate Cell Culture Modeling at Multiple Scales Supports Systematic Shaping of a Monoclonal Antibody Toward a Quality Target
- (2018) Michael Sokolov et al. Biotechnology Journal
- The Use of a GroEL-BLI Biosensor to Rapidly Assess Preaggregate Populations for Antibody Solutions Exhibiting Different Stability Profiles
- (2018) Samantha E. Pace et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validation
- (2018) Jérémie Giorgetti et al. TALANTA
- Sequential Multivariate Cell Culture Modeling at Multiple Scales Supports Systematic Shaping of a Monoclonal Antibody Toward a Quality Target
- (2018) Michael Sokolov et al. Biotechnology Journal
- Nanofluidic device for continuous multiparameter quality assurance of biologics
- (2017) Sung Hee Ko et al. Nature Nanotechnology
- Mechanistic Fermentation Models for Process Design, Monitoring, and Control
- (2017) Lisa Mears et al. TRENDS IN BIOTECHNOLOGY
- Automated N-Glycosylation Sequencing Of Biopharmaceuticals By Capillary Electrophoresis
- (2017) Marton Szigeti et al. Scientific Reports
- Electrochemical detection of protein glycosylation using lectin and protein–gold affinity interactions
- (2016) Sharda Yadav et al. ANALYST
- Capillary electrophoresis for automated on-line monitoring of suspension cultures: Correlating cell density, nutrients and metabolites in near real-time
- (2016) Ala A. Alhusban et al. ANALYTICA CHIMICA ACTA
- Liquid phase separation methods for N-glycosylation analysis of glycoproteins of biomedical and biopharmaceutical interest. A critical review
- (2016) Laszlo Hajba et al. ANALYTICA CHIMICA ACTA
- Spectroscopic sensors for in-line bioprocess monitoring in research and pharmaceutical industrial application
- (2016) Jens Claßen et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Rapid quantitation of monoclonal antibody N-glyco-occupancy and afucosylation using mass spectrometry
- (2016) Suli Liu et al. ANALYTICAL BIOCHEMISTRY
- High-Throughput, Automated Protein A Purification Platform with Multiattribute LC–MS Analysis for Advanced Cell Culture Process Monitoring
- (2016) Jia Dong et al. ANALYTICAL CHEMISTRY
- Structural characterization of expressed monoclonal antibodies by single sample mass spectral analysis after IdeS proteolysis
- (2016) Terence L. Kirley et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices
- (2016) Seyed Ali Mousavi Shaegh et al. Biomicrofluidics
- Investigation of the interactions of critical scale-up parameters (pH, pO2 and pCO2) on CHO batch performance and critical quality attributes
- (2016) Matthias Brunner et al. BIOPROCESS AND BIOSYSTEMS ENGINEERING
- Process performance and product quality in an integrated continuous antibody production process
- (2016) Daniel J. Karst et al. BIOTECHNOLOGY AND BIOENGINEERING
- Robust factor selection in early cell culture process development for the production of a biosimilar monoclonal antibody
- (2016) Michael Sokolov et al. BIOTECHNOLOGY PROGRESS
- Controlling the time evolution of mAb N-linked glycosylation, Part I: Microbioreactor experiments
- (2016) Thomas K. Villiger et al. BIOTECHNOLOGY PROGRESS
- Identifying a robust design space for glycosylation during monoclonal antibody production
- (2016) Melissa M. St. Amand et al. BIOTECHNOLOGY PROGRESS
- Controlling the time evolution of mAb N-linked glycosylation - Part II: Model-based predictions
- (2016) Thomas K. Villiger et al. BIOTECHNOLOGY PROGRESS
- Fast, robust and high-resolution glycosylation profiling of intact monoclonal IgG antibodies using nanoLC-chip-QTOF
- (2016) Joannes F.M. Jacobs et al. CLINICA CHIMICA ACTA
- State-of-the-art technologies for rapid and high-throughput sample preparation and analysis ofN-glycans from antibodies
- (2016) Udayanath Aich et al. ELECTROPHORESIS
- Online bioprocess data generation, analysis, and optimization for parallel fed-batch fermentations in milliliter scale
- (2016) David Benjamin Nickel et al. ENGINEERING IN LIFE SCIENCES
- A scalable software framework for data integration in bioprocess development
- (2016) Ingrid Schmid et al. ENGINEERING IN LIFE SCIENCES
- Adequacy and verifiability of pharmaceutical mixtures and dose units by variographic analysis (Theory of Sampling) – A call for a regulatory paradigm shift
- (2016) Kim H. Esbensen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- High throughput peptide mapping method for analysis of site specific monoclonal antibody oxidation
- (2016) Xiaojuan Li et al. JOURNAL OF CHROMATOGRAPHY A
- Development of a rapid RP-UHPLC–MS method for analysis of modifications in therapeutic monoclonal antibodies
- (2016) Bing Zhang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Cutting-edge capillary electrophoresis characterization of monoclonal antibodies and related products
- (2016) Rabah Gahoual et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Ultrafast and high-throughput N-glycan analysis for monoclonal antibodies
- (2016) Xiaoyu Yang et al. mAbs
- The use of lectin microarray for assessing glycosylation of therapeutic proteins
- (2016) Lei Zhang et al. mAbs
- N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies
- (2016) Sha Sha et al. TRENDS IN BIOTECHNOLOGY
- On-line monitoring of downstream bioprocesses
- (2016) Patricia Roch et al. Current Opinion in Chemical Engineering
- Integrated Microfluidic Lectin Barcode Platform for High-Performance Focused Glycomic Profiling
- (2016) Yuqin Shang et al. Scientific Reports
- Biosimilar structural comparability assessment by NMR: from small proteins to monoclonal antibodies
- (2016) Boštjan Japelj et al. Scientific Reports
- Fluorescence dye-based detection of mAb aggregates in CHO culture supernatants
- (2015) Albert Jesuran Paul et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Site-Specific Protein N- and O-Glycosylation Analysis by a C18-Porous Graphitized Carbon–Liquid Chromatography-Electrospray Ionization Mass Spectrometry Approach Using Pronase Treated Glycopeptides
- (2015) Kathrin Stavenhagen et al. ANALYTICAL CHEMISTRY
- Mapping Monoclonal Antibody Structure by 2D 13C NMR at Natural Abundance
- (2015) Luke W. Arbogast et al. ANALYTICAL CHEMISTRY
- On the Analytical Superiority of 1D NMR for Fingerprinting the Higher Order Structure of Protein Therapeutics Compared to Multidimensional NMR Methods
- (2015) Leszek Poppe et al. ANALYTICAL CHEMISTRY
- Label-Free Glycoprofiling with Multiplex Surface Plasmon Resonance: A Tool To Quantify Sialylation of Erythropoietin
- (2015) Karin P. M. Geuijen et al. ANALYTICAL CHEMISTRY
- Fast Comparative Structural Characterization of Intact Therapeutic Antibodies Using Hydrogen–Deuterium Exchange and Electron Transfer Dissociation
- (2015) Jingxi Pan et al. ANALYTICAL CHEMISTRY
- Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis
- (2015) Yongle Pang et al. ANALYTICAL CHEMISTRY
- Rapid Preparation of Released N-Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection
- (2015) Matthew A. Lauber et al. ANALYTICAL CHEMISTRY
- Carbohydrates on Proteins: Site-Specific Glycosylation Analysis by Mass Spectrometry
- (2015) Zhikai Zhu et al. Annual Review of Analytical Chemistry
- The future of host cell protein (HCP) identification during process development and manufacturing linked to a risk-based management for their control
- (2015) Daniel G. Bracewell et al. BIOTECHNOLOGY AND BIOENGINEERING
- Advanced process monitoring and feedback control to enhance cell culture process production and robustness
- (2015) An Zhang et al. BIOTECHNOLOGY AND BIOENGINEERING
- A framework for real-time glycosylation monitoring (RT-GM) in mammalian cell culture
- (2015) Tharmala Tharmalingam et al. BIOTECHNOLOGY AND BIOENGINEERING
- Bridging the gap between PAT concepts and implementation: An integrated software platform for fermentation
- (2015) Viki R Chopda et al. Biotechnology Journal
- Screening and assessment of performance and molecule quality attributes of industrial cell lines across different fed-batch systems
- (2015) Yolande Rouiller et al. BIOTECHNOLOGY PROGRESS
- Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels
- (2015) Craig Zupke et al. BIOTECHNOLOGY PROGRESS
- Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis
- (2015) Anurag S. Rathore et al. BIOTECHNOLOGY PROGRESS
- Micro sequential injection system as the interfacing device for process analytical applications
- (2015) Chao-Hsiang “Richard” Wu et al. BIOTECHNOLOGY PROGRESS
- Intrinsic fluorescence-basedat situsoft sensor for monitoring monoclonal antibody aggregation
- (2015) Kaveh Ohadi et al. BIOTECHNOLOGY PROGRESS
- Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development
- (2015) Vijay Janakiraman et al. BIOTECHNOLOGY PROGRESS
- Advances in process monitoring tools for cell culture bioprocesses
- (2015) Liang Zhao et al. ENGINEERING IN LIFE SCIENCES
- Sensor systems for bioprocess monitoring
- (2015) Philipp Biechele et al. ENGINEERING IN LIFE SCIENCES
- Artificial Intelligence techniques applied as estimator in chemical process systems – A literature survey
- (2015) Jarinah Mohd Ali et al. EXPERT SYSTEMS WITH APPLICATIONS
- An individual-based modeling approach to simulate the effects of cellular nutrient competition on Escherichia coli K-12 MG1655 colony behavior and interactions in aerobic structured food systems
- (2015) Ignace L.M.M. Tack et al. FOOD MICROBIOLOGY
- Comparison of orthogonal chromatographic and lectin-affinity microarray methods for glycan profiling of a therapeutic monoclonal antibody
- (2015) Matthew C. Cook et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Characterization of free thiol variants of an IgG1 by reversed phase ultra high pressure liquid chromatography coupled with mass spectrometry
- (2015) Hongbin Liu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Control Systems Engineering in Continuous Pharmaceutical Manufacturing May 20–21, 2014 Continuous Manufacturing Symposium
- (2015) Allan S. Myerson et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry
- (2015) Markus Haberger et al. mAbs
- Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics
- (2015) Richard S Rogers et al. mAbs
- Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 2: Mass spectrometric methods
- (2015) Dietmar Reusch et al. mAbs
- Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review
- (2015) Levente L. Simon et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- 2D 1HN, 15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies
- (2015) Luke W. Arbogast et al. PHARMACEUTICAL RESEARCH
- Fiber-Optic Chemical Sensors and Fiber-Optic Bio-Sensors
- (2015) Marie Pospíšilová et al. SENSORS
- Bridging the gap between PAT concepts and implementation: An integrated software platform for fermentation
- (2015) Viki R Chopda et al. Biotechnology Journal
- Review of online coupling of sample preparation techniques with liquid chromatography
- (2014) Jialiang Pan et al. ANALYTICA CHIMICA ACTA
- Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry
- (2014) Richard Y.-C. Huang et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Development of a soft-sensor based on multi-wavelength fluorescence spectroscopy and a dynamic metabolic model for monitoring mammalian cell cultures
- (2014) Kaveh Ohadi et al. BIOTECHNOLOGY AND BIOENGINEERING
- Identification of manipulated variables for a glycosylation control strategy
- (2014) Melissa M. St. Amand et al. BIOTECHNOLOGY AND BIOENGINEERING
- Cross-scale predictive modeling of CHO cell culture growth and metabolites using Raman spectroscopy and multivariate analysis
- (2014) Brandon Berry et al. BIOTECHNOLOGY PROGRESS
- Monitoring an enzyme purification process using on-line and in-line NIR measurements
- (2014) Anna Klimkiewicz et al. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
- Towards real-time monitoring of therapeutic protein quality in mammalian cell processes
- (2014) Daniel A.M. Pais et al. CURRENT OPINION IN BIOTECHNOLOGY
- The development and application of high throughput cultivation technology in bioprocess development
- (2014) Quan Long et al. JOURNAL OF BIOTECHNOLOGY
- Chemometrics application in biotech processes: assessing comparability across processes and scales
- (2014) Anurag S. Rathore et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Multivariate analysis of the effect of operating conditions on hybridoma cell metabolism and glycosylation of produced antibody
- (2014) Amy Green et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Mini-review: soft sensors as means for PAT in the manufacture of bio-therapeutics
- (2014) Carl-Fredrik Mandenius et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Integrating systems analysis and control for implementing process analytical technology in bioprocess development
- (2014) James Gomes et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Rapid process development of chromatographic process using direct analysis in real time mass spectrometry as a process analytical technology tool
- (2014) Binjun Yan et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Theory and practice of size exclusion chromatography for the analysis of protein aggregates
- (2014) Szabolcs Fekete et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- LC-MS/MS Peptide Mapping with Automated Data Processing for Routine Profiling of N-Glycans in Immunoglobulins
- (2014) Bhavana Shah et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods
- (2014) Dietmar Reusch et al. mAbs
- Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process
- (2014) Zhibiao Fu et al. Microbial Cell Factories
- Detection principles and development of microfluidic sensors in the last decade
- (2014) Rahul Antony et al. MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS
- Controllability Analysis of Protein Glycosylation in Cho Cells
- (2014) Melissa M. St. Amand et al. PLoS One
- Therapeutic protein aggregation: mechanisms, design, and control
- (2014) Christopher J. Roberts TRENDS IN BIOTECHNOLOGY
- Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity
- (2014) Frank Delvigne et al. TRENDS IN BIOTECHNOLOGY
- Multivariate PAT solutions for biopharmaceutical cultivation: current progress and limitations
- (2014) Sarah M. Mercier et al. TRENDS IN BIOTECHNOLOGY
- Current advances and strategies towards fully automated sample preparation for regulated LC–MS/MS bioanalysis
- (2014) Naiyu Zheng et al. Bioanalysis
- High throughput process development in biomanufacturing
- (2014) Karol M Łącki Current Opinion in Chemical Engineering
- Overview of integrated models for bioprocess engineering
- (2014) Ajoy Velayudhan Current Opinion in Chemical Engineering
- Glycan analysis: scope and limitations of different techniques—a case for integrated use of LC-MS(/MS) and NMR techniques
- (2013) Meike Fellenberg et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- An automated robotic platform for rapid profiling oligosaccharide analysis of monoclonal antibodies directly from cell culture
- (2013) Margaret Doherty et al. ANALYTICAL BIOCHEMISTRY
- Review of microfluidic microbioreactor technology for high-throughput submerged microbiological cultivation
- (2013) Hanaa M. Hegab et al. Biomicrofluidics
- Identifying analytics for high throughput bioprocess development studies
- (2013) Spyridon Konstantinidis et al. BIOTECHNOLOGY AND BIOENGINEERING
- Microbial heterogeneity affects bioprocess robustness: Dynamic single-cell analysis contributes to understanding of microbial populations
- (2013) Frank Delvigne et al. Biotechnology Journal
- Design of experiments applications in bioprocessing: Concepts and approach
- (2013) Vijesh Kumar et al. BIOTECHNOLOGY PROGRESS
- Development of at-line assay to monitor charge variants of MAbs during production
- (2013) M. M. St. Amand et al. BIOTECHNOLOGY PROGRESS
- Bioprocess data mining using regularized regression and random forests
- (2013) Syeda Hassan et al. BMC Systems Biology
- Evaluation of wavelength selection methods for 2D fluorescence spectra applied to bioprocesses characterization
- (2013) S. S. Masiero et al. BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
- Soft sensor assisted dynamic bioprocess control: Efficient tools for bioprocess development
- (2013) Patrick Sagmeister et al. CHEMICAL ENGINEERING SCIENCE
- Hybrid semi-parametric modeling in process systems engineering: Past, present and future
- (2013) Moritz von Stosch et al. COMPUTERS & CHEMICAL ENGINEERING
- Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications
- (2013) Hui Wei et al. DRUG DISCOVERY TODAY
- Process analytical technology (PAT) tools for the cultivation step in biopharmaceutical production
- (2013) Mathieu Streefland et al. ENGINEERING IN LIFE SCIENCES
- Consistent development of bioprocesses from microliter cultures to the industrial scale
- (2013) Peter Neubauer et al. ENGINEERING IN LIFE SCIENCES
- Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies
- (2013) Hao Zhang et al. FEBS LETTERS
- Perspectives in process analysis
- (2013) Rudolf W. Kessler JOURNAL OF CHEMOMETRICS
- Fast separation of large biomolecules using short monolithic columns
- (2013) Aleš Podgornik et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2μm particles
- (2013) Szabolcs Fekete et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Monitoring Blending of Pharmaceutical Powders with Multipoint NIR Spectroscopy
- (2012) Otto Scheibelhofer et al. AAPS PHARMSCITECH
- Bioreactor monitoring with spectroscopy and chemometrics: a review
- (2012) N. D. Lourenço et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Improved Protein Hydrogen/Deuterium Exchange Mass Spectrometry Platform with Fully Automated Data Processing
- (2012) Zhongqi Zhang et al. ANALYTICAL CHEMISTRY
- Real-time monitoring and control of microbial bioprocesses with focus on the specific growth rate: current state and perspectives
- (2012) Moira Monika Schuler et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Soft sensor control of metabolic fluxes in a recombinant Escherichia coli fed-batch cultivation producing green fluorescence protein
- (2012) Robert Gustavsson et al. BIOPROCESS AND BIOSYSTEMS ENGINEERING
- Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes
- (2012) Patrick Wechselberger et al. BIOPROCESS AND BIOSYSTEMS ENGINEERING
- Automated dynamic fed-batch process and media optimization for high productivity cell culture process development
- (2012) Franklin Lu et al. BIOTECHNOLOGY AND BIOENGINEERING
- How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?
- (2012) Manuel J. T. Carrondo et al. Biotechnology Journal
- Soft sensors in bioprocessing: A status report and recommendations
- (2012) Reiner Luttmann et al. Biotechnology Journal
- Minimizing immunogenicity of biopharmaceuticals by controlling critical quality attributes of proteins
- (2012) Miranda M. C. van Beers et al. Biotechnology Journal
- Quality attributes of recombinant therapeutic proteins: An assessment of impact on safety and efficacy as part of a quality by design development approach
- (2012) Alex Eon-Duval et al. BIOTECHNOLOGY PROGRESS
- Design of Monitoring and Sensor Systems for Bioprocesses by Biomechatronic Methodology
- (2012) C.-F. Mandenius CHEMICAL ENGINEERING & TECHNOLOGY
- Rapid evaluation for heterogeneities in monoclonal antibodies by liquid chromatography/mass spectrometry with a column-switching system
- (2012) Ryosuke Kuribayashi et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Application of the quality by design approach to the drug substance manufacturing process of an Fc fusion protein: Towards a global multi‐step design space
- (2012) Alex Eon-Duval et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Disulfide bond structures of IgG molecules
- (2012) Hongcheng Liu et al. mAbs
- Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars
- (2012) Steven A. Berkowitz et al. NATURE REVIEWS DRUG DISCOVERY
- Process analytical technology (PAT) for biopharmaceuticals
- (2011) Jarka Glassey et al. Biotechnology Journal
- Use of computational fluid dynamics as a tool for establishing process design space for mixing in a bioreactor
- (2011) A. S. Rathore et al. BIOTECHNOLOGY PROGRESS
- Hybrid modeling framework for process analytical technology: Application to Bordetella pertussis cultures
- (2011) M. von Stosch et al. BIOTECHNOLOGY PROGRESS
- A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus
- (2011) Ioscani Jimenez del Val et al. BIOTECHNOLOGY PROGRESS
- Comparison of different estimation techniques for biomass concentration in large scale yeast fermentation
- (2011) A. Hocalar et al. ISA TRANSACTIONS
- Microfluidic sensing: state of the art fabrication and detection techniques
- (2011) Jing Wu et al. JOURNAL OF BIOMEDICAL OPTICS
- Rapid whole monoclonal antibody analysis by mass spectrometry: An Ultra scale-down study of the effect of harvesting by centrifugation on the post-translational modification profile
- (2010) C.Q. Reid et al. BIOTECHNOLOGY AND BIOENGINEERING
- Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns
- (2010) Ioscani Jimenez del Val et al. BIOTECHNOLOGY PROGRESS
- Review of adaptation mechanisms for data-driven soft sensors
- (2010) Petr Kadlec et al. COMPUTERS & CHEMICAL ENGINEERING
- Evaluation of software sensors for on-line estimation of culture conditions in an Escherichia coli cultivation expressing a recombinant protein
- (2010) Benedikt Warth et al. JOURNAL OF BIOTECHNOLOGY
- Assessing monoclonal antibody product quality attribute criticality through clinical studies
- (2010) Andrew M. Goetze et al. mAbs
- ICAS-PAT: A software for design, analysis and validation of PAT systems
- (2009) Ravendra Singh et al. COMPUTERS & CHEMICAL ENGINEERING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now