Process analytical technology (PAT) for biopharmaceuticals

Process analytical technology (PAT) for biopharmaceutical products

(2010) A. S. Rathore et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A model-based systems approach to pharmaceutical product-process design and analysis

(2010) Krist V. Gernaey et al.   CHEMICAL ENGINEERING SCIENCE

Application of mechanistic models to fermentation and biocatalysis for next-generation processes

(2010) Krist V. Gernaey et al.   TRENDS IN BIOTECHNOLOGY

Modelling and simulation of a transketolase mediated reaction: Sensitivity analysis of kinetic parameters

(2009) N.A. Sayar et al.   BIOCHEMICAL ENGINEERING JOURNAL

Identification of cell culture conditions to controlN-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells

(2009) Martin Gawlitzek et al.   BIOTECHNOLOGY AND BIOENGINEERING

Quality-by-Design for biotechnology-related pharmaceuticals

(2009) Carl-Fredrik Mandenius et al.   Biotechnology Journal

Good modeling practice for PAT applications: Propagation of input uncertainty and sensitivity analysis

(2009) Gürkan Sin et al.   BIOTECHNOLOGY PROGRESS

Determining Critical Process Parameters and Process Robustness in Preparative Chromatography - A Model-Based Approach

(2009) M. Degerman et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Global Sensitivity Analysis Challenges in Biological Systems Modeling

(2009) A. Kiparissides et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

On-line estimation of biomass, glucose and ethanol in Saccharomyces cerevisiae cultivations using in-situ multi-wavelength fluorescence and software sensors

(2009) Peter Ödman et al.   JOURNAL OF BIOTECHNOLOGY

Matrix notation for efficient development offirst-principlesmodels within PAT applications: Integrated modeling of antibiotic production withStreptomyces coelicolor

(2008) Gürkan Sin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Model-based computer-aided framework for design of process monitoring and analysis systems

(2008) Ravendra Singh et al.   COMPUTERS & CHEMICAL ENGINEERING