Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process
出版年份 2018 全文链接
标题
Evolving and Expanding the Roles of Mitophagy as a Homeostatic and Pathogenic Process
作者
关键词
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出版物
PHYSIOLOGICAL REVIEWS
Volume 99, Issue 1, Pages 853-892
出版商
American Physiological Society
发表日期
2018-12-12
DOI
10.1152/physrev.00005.2018
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The coming of age of chaperone-mediated autophagy
- (2018) Susmita Kaushik et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A
- (2018) Agostinho G. Rocha et al. SCIENCE
- Evolving Concepts of Mitochondrial Dynamics
- (2018) Gerald W. Dorn Annual Review of Physiology
- Autophagy maintains the metabolism and function of young and old stem cells
- (2017) Theodore T. Ho et al. NATURE
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
- (2017) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity
- (2017) Verónica Eisner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
- (2017) Jesse S. Kerr et al. TRENDS IN NEUROSCIENCES
- A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance
- (2017) Babette C. Hammerling et al. Nature Communications
- Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
- (2017) Rhianna C. Laker et al. Nature Communications
- Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress
- (2017) Kim Han et al. Scientific Reports
- PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
- (2017) Yunjong Lee et al. Cell Reports
- Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox
- (2017) Mathew Suji Eapen et al. Expert Review of Respiratory Medicine
- Mitophagy in Parkinson’s Disease: Pathogenic and Therapeutic Implications
- (2017) Fei Gao et al. Frontiers in Neurology
- Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease
- (2017) Brianada Koentjoro et al. Scientific Reports
- Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate
- (2016) Alejandro Vazquez-Martin et al. Aging-US
- Structural basis for the phosphorylation of FUNDC1 LIR as a molecular switch of mitophagy
- (2016) Yao Kuang et al. Autophagy
- SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages
- (2016) Min-Ji Kim et al. Autophagy
- Cellular Metabolism and Induced Pluripotency
- (2016) Jun Wu et al. CELL
- NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria
- (2016) Zhenyu Zhong et al. CELL
- NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy
- (2016) V E Kagan et al. CELL DEATH AND DIFFERENTIATION
- Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles
- (2016) E Fiacco et al. CELL DEATH AND DIFFERENTIATION
- Autophagy and Alzheimer’s Disease
- (2016) Qian Li et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE
- (2016) Akihiro Shirakabe et al. CIRCULATION
- Aging and Autophagy in the Heart
- (2016) Akihiro Shirakabe et al. CIRCULATION RESEARCH
- Novel ESCRT functions in cell biology: spiraling out of control?
- (2016) Coen Campsteijn et al. CURRENT OPINION IN CELL BIOLOGY
- Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis
- (2016) Jennifer L. Larson-Casey et al. IMMUNITY
- BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy
- (2016) Tongmei Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria in lung disease
- (2016) Suzanne M. Cloonan et al. JOURNAL OF CLINICAL INVESTIGATION
- Potential biomarkers to follow the progression and treatment response of Huntington’s disease
- (2016) Marie-Hélène Disatnik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis
- (2016) Kenji Kobayashi et al. JOURNAL OF IMMUNOLOGY
- Receptor-mediated mitophagy
- (2016) Osamu Yamaguchi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Autophagy core machinery: overcoming spatial barriers in neurons
- (2016) Aileen R. Ariosa et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition
- (2016) Jeong-sun Ju et al. Journal of Physiological Sciences
- Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system
- (2016) Virgilio J. J. Cadete et al. JOURNAL OF PHYSIOLOGY-LONDON
- Correcting mitochondrial fusion by manipulating mitofusin conformations
- (2016) Antonietta Franco et al. NATURE
- Autophagy maintains stemness by preventing senescence
- (2016) Laura García-Prat et al. NATURE
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
- (2016) Andrew S. Moore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
- (2016) Rebecca Rojansky et al. eLife
- Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice
- (2015) Jessica A. Williams et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Deubiquitinating enzymes regulate PARK2-mediated mitophagy
- (2015) Yuqing Wang et al. Autophagy
- PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis
- (2015) Saburo Ito et al. Autophagy
- Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling
- (2015) Rohit A Sinha et al. Autophagy
- Mitochondrial dysfunction in cardiac aging
- (2015) Autumn Tocchi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX
- (2015) Paul A. Ney BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondrial DNA Variation in Human Radiation and Disease
- (2015) Douglas C. Wallace CELL
- Mitochondrial ROS Signaling in Organismal Homeostasis
- (2015) Gerald S. Shadel et al. CELL
- Mitoconfusion: Noncanonical Functioning of Dynamism Factors in Static Mitochondria of the Heart
- (2015) Moshi Song et al. Cell Metabolism
- Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts
- (2015) Moshi Song et al. Cell Metabolism
- How Mitochondrial Dynamism Orchestrates Mitophagy
- (2015) O. S. Shirihai et al. CIRCULATION RESEARCH
- Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse HeartsNovelty and Significance
- (2015) Moshi Song et al. CIRCULATION RESEARCH
- The retromer complex in development and disease
- (2015) S. Wang et al. DEVELOPMENT
- Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease
- (2015) S. Hwang et al. EMBO Molecular Medicine
- Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
- (2015) A. H. Chourasia et al. EMBO REPORTS
- Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy
- (2015) Weili Tian et al. FEBS LETTERS
- Mitochondrial biogenesis and dynamics in the developing and diseased heart
- (2015) Gerald W. Dorn et al. GENES & DEVELOPMENT
- Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains
- (2015) Xuan Ye et al. HUMAN MOLECULAR GENETICS
- TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation
- (2015) Gen Matsumoto et al. HUMAN MOLECULAR GENETICS
- Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival
- (2015) Amabel M. Orogo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death
- (2015) Hong-guang Xia et al. JOURNAL OF CELL BIOLOGY
- Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1
- (2015) Seung Baek Lee et al. MOLECULAR CELL
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans
- (2015) Konstantinos Palikaras et al. NATURE
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming
- (2015) Tianhua Ma et al. NATURE CELL BIOLOGY
- Huntingtin functions as a scaffold for selective macroautophagy
- (2015) Yan-Ning Rui et al. NATURE CELL BIOLOGY
- USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
- (2015) Christian N. Cunningham et al. NATURE CELL BIOLOGY
- The central role of muscle stem cells in regenerative failure with aging
- (2015) Helen M Blau et al. NATURE MEDICINE
- Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
- (2015) Wenzhang Wang et al. NATURE MEDICINE
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure
- (2015) Liuji Chen et al. NEUROBIOLOGY OF AGING
- Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
- (2015) Alicia M. Pickrell et al. NEURON
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration
- (2015) Daniel A. Stevens et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication
- (2015) Dominik Barthelme et al. PROTEIN SCIENCE
- Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice
- (2015) G. Gong et al. SCIENCE
- Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
- (2015) Beth Levine et al. TRENDS IN CELL BIOLOGY
- E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1
- (2015) Kun Wang et al. Nature Communications
- Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance
- (2015) Jiyong Liang et al. Nature Communications
- Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
- (2015) Tomokazu Murakawa et al. Nature Communications
- Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan
- (2015) Dominik Bernhardt et al. Scientific Reports
- Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis
- (2015) Avignat S. Patel et al. PLoS One
- MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury
- (2014) Praveen Mannam et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Senescence-Associated Secretory Phenotype and Its Possible Role in Chronic Obstructive Pulmonary Disease
- (2014) Manish Kumar et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Autophagy is not required to sustain exercise and PRKAA1/AMPK activity but is important to prevent mitochondrial damage during physical activity
- (2014) Francesca Lo Verso et al. Autophagy
- BECN1 is involved in the initiation of mitophagy
- (2014) Vinay Choubey et al. Autophagy
- AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
- (2014) F Strappazzon et al. CELL DEATH AND DIFFERENTIATION
- The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease
- (2014) Angelika B. Harbauer et al. Cell Metabolism
- Super-Suppression of Mitochondrial Reactive Oxygen Species Signaling Impairs Compensatory Autophagy in Primary Mitophagic Cardiomyopathy
- (2014) Moshi Song et al. CIRCULATION RESEARCH
- Cardiac Mitochondria and Reactive Oxygen Species Generation
- (2014) Yeong-Renn Chen et al. CIRCULATION RESEARCH
- Role of Cardiolipin in Mitochondrial Diseases and Apoptosis
- (2014) R. Santucci et al. CURRENT MEDICINAL CHEMISTRY
- Paternal Mitochondrial Destruction after Fertilization Is Mediated by a Common Endocytic and Autophagic Pathway in Drosophila
- (2014) Yoav Politi et al. DEVELOPMENTAL CELL
- A new pathway for mitochondrial quality control: mitochondrial-derived vesicles
- (2014) A. Sugiura et al. EMBO JOURNAL
- USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin
- (2014) T. M. Durcan et al. EMBO JOURNAL
- Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
- (2014) Gian-Luca McLelland et al. EMBO JOURNAL
- ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
- (2014) W. Wu et al. EMBO REPORTS
- The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
- (2014) Tom Cornelissen et al. HUMAN MOLECULAR GENETICS
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery
- (2014) S. Schuck et al. JOURNAL OF CELL SCIENCE
- Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD
- (2014) Kenji Mizumura et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelial PINK1 Mediates the Protective Effects of NLRP3 Deficiency during Lethal Oxidant Injury
- (2014) Y. Zhang et al. JOURNAL OF IMMUNOLOGY
- A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy
- (2014) Guo Chen et al. MOLECULAR CELL
- PINK1-PARKIN Interplay: Down to Ubiquitin Phosphorylation
- (2014) Alexandra Stolz et al. MOLECULAR CELL
- Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis
- (2014) Alban Ordureau et al. MOLECULAR CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
- (2014) Baris Bingol et al. NATURE
- Geriatric muscle stem cells switch reversible quiescence into senescence
- (2014) Pedro Sousa-Victor et al. NATURE
- Mitochondrial dynamics and inheritance during cell division, development and disease
- (2014) Prashant Mishra et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
- (2014) Daniel J Klionsky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling
- (2014) Rimpy Dhingra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of mitochondria in alcoholic liver disease
- (2014) Fatiha Nassir WORLD JOURNAL OF GASTROENTEROLOGY
- Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes
- (2014) Shinya Honda et al. Nature Communications
- Parkin Sensitizes toward Apoptosis Induced by Mitochondrial Depolarization through Promoting Degradation of Mcl-1
- (2014) Richard G. Carroll et al. Cell Reports
- Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state
- (2013) Cécile Jamart et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics
- (2013) Emanuele Marzetti et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Pathogenesis of Idiopathic Pulmonary Fibrosis
- (2013) Paul J. Wolters et al. Annual Review of Pathology-Mechanisms of Disease
- PINK1 is degraded through the N-end rule pathway
- (2013) Koji Yamano et al. Autophagy
- The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
- (2013) Seok Min Jin et al. Autophagy
- New insights into the function and regulation of mitochondrial fission
- (2013) Hidenori Otera et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitochondrial Contagion Induced by Parkin Deficiency in Drosophila Hearts and Its Containment by Suppressing Mitofusin
- (2013) Poonam Bhandari et al. CIRCULATION RESEARCH
- Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance
- (2013) Vitor A. Lira et al. FASEB JOURNAL
- Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
- (2013) Melissa K. McCoy et al. HUMAN MOLECULAR GENETICS
- Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models
- (2013) Jordi Magrané et al. HUMAN MOLECULAR GENETICS
- Macrophage Migration Inhibitory Factor Deletion Exacerbates Pressure Overload–Induced Cardiac Hypertrophy Through Mitigating Autophagy
- (2013) Xihui Xu et al. HYPERTENSION
- Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury
- (2013) Gouri Yogalingam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
- (2013) Kei Okatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- The ubiquitin ligase parkin mediates resistance to intracellular pathogens
- (2013) Paolo S. Manzanillo et al. NATURE
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
- (2013) Charleen T. Chu et al. NATURE CELL BIOLOGY
- VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations
- (2013) Nam Chul Kim et al. NEURON
- Deubiquitylases From Genes to Organism
- (2013) Michael J. Clague et al. PHYSIOLOGICAL REVIEWS
- Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury
- (2013) Hilary K. Siddall et al. PLoS One
- mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology
- (2013) C. Betz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Kissing and nanotunneling mediate intermitochondrial communication in the heart
- (2013) X. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
- (2013) J.-F. Trempe et al. SCIENCE
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- Selective escape of proteins from the mitochondria during mitophagy
- (2013) Shotaro Saita et al. Nature Communications
- Bit-by-bit autophagic removal of parkin-labelled mitochondria
- (2013) Jin-Yi Yang et al. Nature Communications
- Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart
- (2013) Atsushi Hoshino et al. Nature Communications
- Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy
- (2013) Hagai Abeliovich et al. Nature Communications
- Animal Models of Parkinson's Disease: Vertebrate Genetics
- (2013) Y. Lee et al. Cold Spring Harbor Perspectives in Medicine
- Drosophila as a Model to Study Mitochondrial Dysfunction in Parkinson's Disease
- (2013) M. Guo Cold Spring Harbor Perspectives in Medicine
- Insufficient autophagy in idiopathic pulmonary fibrosis
- (2012) Jun Araya et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
- (2012) Kati J. Ahlqvist et al. Cell Metabolism
- Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
- (2012) Weijiao Huang et al. CELL RESEARCH
- A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
- (2012) Vincent Soubannier et al. CURRENT BIOLOGY
- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- Mitochondria-targeted catalase reduces abnormal APP processing, amyloid production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension
- (2012) P. Mao et al. HUMAN MOLECULAR GENETICS
- Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction
- (2012) Dieter A. Kubli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
- (2012) Rita A. Hanna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
- (2012) Noriko Kondo-Okamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants
- (2012) Manu Sharma et al. JOURNAL OF MEDICAL GENETICS
- BNip3 Regulates Mitochondrial Function and Lipid Metabolism in the Liver
- (2012) D. Glick et al. MOLECULAR AND CELLULAR BIOLOGY
- Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy
- (2012) A. Orsi et al. MOLECULAR BIOLOGY OF THE CELL
- Phenotypic variability ofparkinmutations in single kindred
- (2012) Brianada Koentjoro et al. MOVEMENT DISORDERS
- The clonal and mutational evolution spectrum of primary triple-negative breast cancers
- (2012) Sohrab P. Shah et al. NATURE
- The aged niche disrupts muscle stem cell quiescence
- (2012) Joe V. Chakkalakal et al. NATURE
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- The Molecular Pathology of Alzheimer's Disease
- (2012) Charles R. Harrington NEUROIMAGING CLINICS OF NORTH AMERICA
- Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan
- (2012) Sara Sigismund et al. PHYSIOLOGICAL REVIEWS
- Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis
- (2012) T. Willinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Delivery of endosomes to lysosomes via microautophagy in the visceral endoderm of mouse embryos
- (2012) Nobuyuki Kawamura et al. Nature Communications
- A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
- (2011) Alexander Zimprich et al. AMERICAN JOURNAL OF HUMAN GENETICS
- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
- (2011) Joo-Ho Shin et al. CELL
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover
- (2011) S Rikka et al. CELL DEATH AND DIFFERENTIATION
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Microautophagy: lesser-known self-eating
- (2011) Wen-wen Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis
- (2011) Yun Chen et al. CIRCULATION RESEARCH
- Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation
- (2011) Mariusz Karbowski et al. CURRENT OPINION IN CELL BIOLOGY
- p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death
- (2011) Xi Feng et al. EMBO JOURNAL
- Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
- (2011) Flavie Strappazzon et al. EMBO JOURNAL
- Activation of autophagy protects against acetaminophen-induced hepatotoxicity
- (2011) Hong-Min Ni et al. HEPATOLOGY
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane
- (2011) Saori R. Yoshii et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin Ubiquitinates Drp1 for Proteasome-dependent Degradation
- (2011) Hongxia Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
- (2011) Cathrin Meissner et al. JOURNAL OF NEUROCHEMISTRY
- Parkin Interacts with Ambra1 to Induce Mitophagy
- (2011) C. Van Humbeeck et al. JOURNAL OF NEUROSCIENCE
- Phosphorylation of Serine 114 on Atg32 mediates mitophagy
- (2011) Yoshimasa Aoki et al. MOLECULAR BIOLOGY OF THE CELL
- During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
- (2011) Ligia C. Gomes et al. NATURE CELL BIOLOGY
- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
- (2011) Aleksandar Rakovic et al. PLoS One
- Control of Mitochondrial Morphology Through Differential Interactions of Mitochondrial Fusion and Fission Proteins
- (2011) Pinwei Huang et al. PLoS One
- Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
- (2011) A. S. Rambold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
- (2011) C. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
- (2011) F. Billia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin ligase Nedd4 promotes -synuclein degradation by the endosomal-lysosomal pathway
- (2011) G. K. Tofaris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans Embryos
- (2011) M. Sato et al. SCIENCE
- Postfertilization Autophagy of Sperm Organelles Prevents Paternal Mitochondrial DNA Transmission
- (2011) S. Al Rawi et al. SCIENCE
- Return to the fetal gene program
- (2010) Heinrich Taegtmeyer et al. Annals of the New York Academy of Sciences
- Regulation of autophagy by transforming growth factor-β (TGF-β) signaling
- (2010) Hiroshi I. Suzuki et al. Autophagy
- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
- (2010) Derek Narendra et al. Autophagy
- Inhibition of autophagy in the heart induces age-related cardiomyopathy
- (2010) Manabu Taneike et al. Autophagy
- How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?
- (2010) Elena Ziviani et al. Autophagy
- Cardiotoxicity of anthracycline agents for the treatment of cancer: Systematic review and meta-analysis of randomised controlled trials
- (2010) Lesley A Smith et al. BMC CANCER
- The diverse functions of GAPDH: Views from different subcellular compartments
- (2010) Carlos Tristan et al. CELLULAR SIGNALLING
- Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes
- (2010) Emélie Braschi et al. CURRENT BIOLOGY
- LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
- (2010) Hilla Weidberg et al. EMBO JOURNAL
- p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
- (2010) Kei Okatsu et al. GENES TO CELLS
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming
- (2010) Wen-Xing Ding et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Mitofusin 2 Is Necessary for Transport of Axonal Mitochondria and Interacts with the Miro/Milton Complex
- (2010) A. Misko et al. JOURNAL OF NEUROSCIENCE
- Huntington's disease: from molecular pathogenesis to clinical treatment
- (2010) Christopher A Ross et al. LANCET NEUROLOGY
- Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
- (2010) Daisuke Nakada et al. NATURE
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
- (2010) Boyi Gan et al. NATURE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Selective autophagy: ubiquitin-mediated recognition and beyond
- (2010) Claudine Kraft et al. NATURE CELL BIOLOGY
- Eaten alive: a history of macroautophagy
- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
- (2010) Angela C. Poole et al. PLoS One
- Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
- (2010) M. M. Lipinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
- (2010) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)
- (2010) J. S. Oakhill et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
- (2010) D. F. Egan et al. SCIENCE
- Cardiac Aging in Mice and Humans: The Role of Mitochondrial Oxidative Stress
- (2010) Dao-Fu Dai et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Mitochondrial Pruning by Nix and BNip3: An Essential Function for Cardiac-Expressed Death Factors
- (2010) Gerald W. Dorn Journal of Cardiovascular Translational Research
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy
- (2009) Melanie Schwarten et al. Autophagy
- Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions
- (2009) Na Rae Hwang et al. BIOCHEMICAL JOURNAL
- Functional complementation of mitochondrial DNAs: Mobilizing mitochondrial genetics against dysfunction
- (2009) Eric A. Schon et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
- (2009) Tomotake Kanki et al. DEVELOPMENTAL CELL
- Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
- (2009) Koji Okamoto et al. DEVELOPMENTAL CELL
- Mitochondrial ‘kiss-and-run’: interplay between mitochondrial motility and fusion–fission dynamics
- (2009) Xingguo Liu et al. EMBO JOURNAL
- Nix is a selective autophagy receptor for mitochondrial clearance
- (2009) Ivana Novak et al. EMBO REPORTS
- Hypoxia-induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia-tolerant mole rat, Spalax ehrenbergi
- (2009) Mark Band et al. FASEB JOURNAL
- What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy?
- (2009) Jakob D. Wikstrom et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes
- (2009) H. H. Pua et al. JOURNAL OF IMMUNOLOGY
- Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
- (2009) G. Bellot et al. MOLECULAR AND CELLULAR BIOLOGY
- Discovery of Atg5/Atg7-independent alternative macroautophagy
- (2009) Yuya Nishida et al. NATURE
- Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
- (2009) Selvaraju Veeriah et al. NATURE GENETICS
- AMPK in Health and Disease
- (2009) Gregory R. Steinberg et al. PHYSIOLOGICAL REVIEWS
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The rotary mechanism of the ATP synthase
- (2008) Robert K. Nakamoto et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- Role of glyceraldehyde-3-phosphate dehydrogenase in vesicular transport from Golgi apparatus to endoplasmic reticulum
- (2008) A. V. Bryksin et al. BIOCHEMISTRY-MOSCOW
- Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
- (2008) M. Kundu et al. BLOOD
- Ubiquitin Chain Editing Revealed by Polyubiquitin Linkage-Specific Antibodies
- (2008) Kim Newton et al. CELL
- Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation
- (2008) Abhinav Diwan et al. CIRCULATION
- Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers
- (2008) Margaret Neuspiel et al. CURRENT BIOLOGY
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- On the mechanism of organelle degradation in the vertebrate lens
- (2008) Steven Bassnett EXPERIMENTAL EYE RESEARCH
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Endoplasmic reticulum–mitochondria crosstalk in NIX-mediated murine cell death
- (2008) Abhinav Diwan et al. JOURNAL OF CLINICAL INVESTIGATION
- Mitochondria in the aetiology and pathogenesis of Parkinson's disease
- (2008) Anthony HV Schapira LANCET NEUROLOGY
- Regulation of Mitochondrial Morphology by USP30, a Deubiquitinating Enzyme Present in the Mitochondrial Outer Membrane
- (2008) Nobuhiro Nakamura et al. MOLECULAR BIOLOGY OF THE CELL
- Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
- (2008) Eisuke Itakura et al. MOLECULAR BIOLOGY OF THE CELL
- Essential role for Nix in autophagic maturation of erythroid cells
- (2008) Hector Sandoval et al. NATURE
- The role of oxygen availability in embryonic development and stem cell function
- (2008) M. Celeste Simon et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondria in Neuroplasticity and Neurological Disorders
- (2008) Mark P. Mattson et al. NEURON
- Parkin as a tumor suppressor gene for hepatocellular carcinoma
- (2008) M Fujiwara et al. ONCOGENE
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