AMPK in Health and Disease

AMP-activated protein kinase control of fat metabolism in skeletal muscle

(2009) D. M. Thomson et al.   Acta Physiologica

The Glycogen-Binding Domain on the AMPK β Subunit Allows the Kinase to Act as a Glycogen Sensor

(2009) Andrew McBride et al.   Cell Metabolism

AMP-Activated Protein Kinase Phosphorylates Retinoblastoma Protein to Control Mammalian Brain Development

(2009) Biplab Dasgupta et al.   DEVELOPMENTAL CELL

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells

(2008) Hélène Klein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

(2008) Kei Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK

(2008) Peter F. Mount et al.   ATHEROSCLEROSIS

Insulin action on glucose transporters through molecular switches, tracks and tethers

(2008) Hilal Zaid et al.   BIOCHEMICAL JOURNAL

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

(2008) Shuai Chen et al.   BIOCHEMICAL JOURNAL

Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites

(2008) Neil FW Saunders et al.   BMC BIOINFORMATICS

Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas

(2008) C. M. Contreras et al.   CANCER RESEARCH

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

(2008) S. Gurumurthy et al.   CANCER RESEARCH

SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons

(2008) Ying Li et al.   Cell Metabolism

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

(2008) John W. Scott et al.   CHEMISTRY & BIOLOGY

AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5

(2008) S. L. McGee et al.   DIABETES

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I: A Mechanism for the Action of Berberine to Activate AMP-Activated Protein Kinase and Improve Insulin Action

(2008) N. Turner et al.   DIABETES

Metabolic Remodeling in Adipocytes Promotes Ciliary Neurotrophic Factor-Mediated Fat Loss in Obesity

(2008) Seamus Crowe et al.   ENDOCRINOLOGY

Small Molecule Antagonizes Autoinhibition and Activates AMP-activated Protein Kinase in Cells

(2008) Tao Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of GLUT4 Translocation by Tbc1d1, a Rab GTPase-activating Protein Abundant in Skeletal Muscle, Is Partially Relieved by AMP-activated Protein Kinase Activation

(2008) Jose A. Chavez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of TBC1D1 as an Insulin-, AICAR-, and Contraction-stimulated Signaling Nexus in Mouse Skeletal Muscle

(2008) Eric B. Taylor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drosophila alicorn Is a Neuronal Maintenance Factor Protecting against Activity-Induced Retinal Degeneration

(2008) M. R. Spasic et al.   JOURNAL OF NEUROSCIENCE

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation

(2008) Nicolas Dzamko et al.   JOURNAL OF PHYSIOLOGY-LONDON

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Thyroid Hormone Activates Adenosine 5′-Monophosphate-Activated Protein Kinase via Intracellular Calcium Mobilization and Activation of Calcium/Calmodulin-Dependent Protein Kinase Kinase-β

(2008) Masako Yamauchi et al.   MOLECULAR ENDOCRINOLOGY

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

(2008) I Ben Sahra et al.   ONCOGENE

Berberine improves glucose metabolism through induction of glycolysis

(2007) Jun Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SNF1/AMPK pathways in yeast

(2007) Kristina Hedbacker   Frontiers in Bioscience-Landmark

AMPK and transcriptional regulation

(2007) Sean et al.   Frontiers in Bioscience-Landmark

BRCA1 and acetyl-CoA carboxylase: The metabolic syndrome of breast cancer

(2007) Joan Brunet et al.   MOLECULAR CARCINOGENESIS

Single nucleotide polymorphisms in genes encoding LKB1 (STK11), TORC2 (CRTC2) and AMPK α2-subunit (PRKAA2) and risk of type 2 diabetes

(2007) Parvaneh Keshavarz et al.   MOLECULAR GENETICS AND METABOLISM