Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
出版年份 2016 全文链接
标题
Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 24, Pages E3349-E3358
出版商
Proceedings of the National Academy of Sciences
发表日期
2016-06-01
DOI
10.1073/pnas.1523810113
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease
- (2015) Cyril Pottier et al. ACTA NEUROPATHOLOGICA
- TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation
- (2015) Gen Matsumoto et al. HUMAN MOLECULAR GENETICS
- The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
- (2015) Jin-Mi Heo et al. MOLECULAR CELL
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
- The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy
- (2015) David A. Tumbarello et al. PLoS Pathogens
- A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin
- (2015) Kapil Sirohi et al. PLoS One
- Amyotrophic lateral sclerosis onset is influenced by the burden of rare variants in known amyotrophic lateral sclerosis genes
- (2014) Janet Cady et al. ANNALS OF NEUROLOGY
- Mitochondria as signaling organelles
- (2014) Navdeep S Chandel BMC BIOLOGY
- Pink1, the first ubiquitin kinase
- (2014) X. Zheng et al. EMBO JOURNAL
- Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
- (2014) Ghazaleh Ashrafi et al. JOURNAL OF CELL BIOLOGY
- PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
- (2014) Lesley A. Kane et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial Dysfunction Induces Sarm1-Dependent Cell Death in Sensory Neurons
- (2014) D. W. Summers et al. JOURNAL OF NEUROSCIENCE
- Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
- (2014) Vladimir Rogov et al. MOLECULAR CELL
- Ubiquitin is phosphorylated by PINK1 to activate parkin
- (2014) Fumika Koyano et al. NATURE
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of ‘eat-me’ signals and autophagy cargo receptors in innate immunity
- (2013) Keith B. Boyle et al. CURRENT OPINION IN MICROBIOLOGY
- Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons
- (2012) Qian Cai et al. CURRENT BIOLOGY
- Optineurin and amyotrophic lateral sclerosis
- (2012) Hirofumi Maruyama et al. Geriatrics & Gerontology International
- A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany
- (2012) Jochen H. Weishaupt et al. NEUROBIOLOGY OF AGING
- Mitochondrial Ca2+ homeostasis: mechanism, role, and tissue specificities
- (2012) Paola Pizzo et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation
- (2011) Hidefumi Ito et al. ACTA NEUROPATHOLOGICA
- Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells
- (2011) Jin-Yi Yang et al. Autophagy
- Novel cross-talk within the IKK family controls innate immunity
- (2011) Kristopher Clark et al. BIOCHEMICAL JOURNAL
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
- (2009) Teresa L M Thurston et al. NATURE IMMUNOLOGY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More