Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

(2016) J. Julie Wu et al.   Aging-US

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes

(2011) Youngil Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control

(2011) Daolin Tang et al.   Cell Metabolism

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkin Interacts with Ambra1 to Induce Mitophagy

(2011) C. Van Humbeeck et al.   JOURNAL OF NEUROSCIENCE

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

(2011) Chengqun Huang et al.   PLoS One

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

(2011) George W. Rogers et al.   PLoS One

PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

(2011) F. Billia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Autophagy in the Heart: “You Only Live Twice”

(2010) Yaron Aviv et al.   ANTIOXIDANTS & REDOX SIGNALING

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

Mitochondrial turnover in the heart

(2010) Roberta A. Gottlieb et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

(2010) Dale W. Hailey et al.   CELL

Juvenile Exposure to Anthracyclines Impairs Cardiac Progenitor Cell Function and Vascularization Resulting in Greater Susceptibility to Stress-Induced Myocardial Injury in Adult Mice

(2010) Chengqun Huang et al.   CIRCULATION

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

(2010) Joo-Yong Lee et al.   JOURNAL OF CELL BIOLOGY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Functional Significance and Morphological Characterization of Starvation-Induced Autophagy in the Adult Heart

(2009) Hiromitsu Kanamori et al.   AMERICAN JOURNAL OF PATHOLOGY

Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy

(2009) Melanie Schwarten et al.   Autophagy

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion

(2008) Dieter A. Kubli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration

(2008) T. C. Frank-Cannon et al.   JOURNAL OF NEUROSCIENCE