Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics
出版年份 2013 全文链接
标题
Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics
作者
关键词
-
出版物
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Volume 305, Issue 4, Pages H459-H476
出版商
American Physiological Society
发表日期
2013-06-08
DOI
10.1152/ajpheart.00936.2012
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice
- (2016) Sokrates Stein et al. Aging-US
- The NADPH Oxidase Nox4 and Aging in the Heart
- (2016) Tetsuro Ago et al. Aging-US
- Autophagy in endothelial progenitor cells is cytoprotective in hypoxic conditions
- (2012) Hai-Jie Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Enhancement of 26S Proteasome Functionality Connects Oxidative Stress and Vascular Endothelial Inflammatory Response in Diabetes Mellitus
- (2012) Hongtao Liu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Staying cool in difficult times: Mitochondrial dynamics, quality control and the stress response
- (2012) Timothy E. Shutt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitophagy: mechanisms, pathophysiological roles, and analysis
- (2012) Wen-Xing Ding et al. BIOLOGICAL CHEMISTRY
- Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy
- (2012) Riccardo Calvani et al. BIOLOGICAL CHEMISTRY
- The shape of things to come: mitochondrial fusion and fission in the adult heart
- (2012) A. R. Hall et al. CARDIOVASCULAR RESEARCH
- Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
- (2012) Jerome Piquereau et al. CARDIOVASCULAR RESEARCH
- Autophagy and cardiovascular aging
- (2012) Sreejayan Nair et al. CELL CYCLE
- Mitochondria and Cardiovascular Aging
- (2012) Dao-Fu Dai et al. CIRCULATION RESEARCH
- Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging
- (2012) Debapriya Dutta et al. CIRCULATION RESEARCH
- Insulin-Like Growth Factor 1 Alleviates High-Fat Diet–Induced Myocardial Contractile Dysfunction
- (2012) Yingmei Zhang et al. HYPERTENSION
- Translational evidence that impaired autophagy contributes to arterial ageing
- (2012) Thomas J. LaRocca et al. JOURNAL OF PHYSIOLOGY-LONDON
- Diverse Roles of Growth Hormone and Insulin-Like Growth Factor-1 in Mammalian Aging: Progress and Controversies
- (2012) W. E. Sonntag et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Circulating Factors Induced by Caloric Restriction in the Nonhuman Primate Macaca Mulatta Activate Angiogenic Processes in Endothelial Cells
- (2012) A. Csiszar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The Emerging Role of IGF-1 Deficiency in Cardiovascular Aging: Recent Advances
- (2012) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Age-Associated Proinflammatory Secretory Phenotype in Vascular Smooth Muscle Cells From the Non-human Primate Macaca mulatta: Reversal by Resveratrol Treatment
- (2012) A. Csiszar et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
- (2012) Takafumi Oka et al. NATURE
- Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
- (2012) Lei Liu et al. NATURE CELL BIOLOGY
- Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
- (2012) M. Vos et al. SCIENCE
- Mitochondrial Fission, Fusion, and Stress
- (2012) R. J. Youle et al. SCIENCE
- Cerebrovascular Disease and Mechanisms of Cognitive Impairment
- (2012) Raj N. Kalaria STROKE
- The neurobiology of sirtuins and their role in neurodegeneration
- (2012) Gizem Donmez TRENDS IN PHARMACOLOGICAL SCIENCES
- Mitochondrial network energetics in the heart
- (2012) Miguel A. Aon et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
- (2011) Antero Salminen et al. AGEING RESEARCH REVIEWS
- Caloric restriction: powerful protection for the aging heart and vasculature
- (2011) Edward P. Weiss et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response
- (2011) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
- (2011) Kyriakos N. Papanicolaou et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Resveratrol in cardiovascular health and disease
- (2011) Goran Petrovski et al. Annals of the New York Academy of Sciences
- Insulin-like growth factor-1 receptor activation prevents hydrogen peroxide-induced oxidative stress, mitochondrial dysfunction and apoptosis
- (2011) Chang-Ning Hao et al. APOPTOSIS
- Mitochondrial Oxidative Stress in Aortic Stiffening With Age
- (2011) Rui-Hai Zhou et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Effects of coenzyme Q10 on vascular endothelial function in humans: A meta-analysis of randomized controlled trials
- (2011) Linggen Gao et al. ATHEROSCLEROSIS
- A comprehensive glossary of autophagy-related molecules and processes (2ndedition)
- (2011) Daniel J Klionsky et al. Autophagy
- Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
- (2011) Seon-Jin Lee et al. Autophagy
- AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
- (2011) Zhonglin Xie et al. Autophagy
- Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum
- (2011) Dalibor Mijaljica et al. Autophagy
- Microautophagy: lesser-known self-eating
- (2011) Wen-wen Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure
- (2011) Dao-Fu Dai et al. CIRCULATION RESEARCH
- Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis
- (2011) Yun Chen et al. CIRCULATION RESEARCH
- Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice
- (2011) Z. Xie et al. DIABETES
- The role of free radical generation in increasing cerebrovascular permeability
- (2011) Paul A. Fraser FREE RADICAL BIOLOGY AND MEDICINE
- Caloric Restriction Ameliorates Angiotensin II–Induced Mitochondrial Remodeling and Cardiac Hypertrophy
- (2011) Piet Finckenberg et al. HYPERTENSION
- The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease
- (2011) M. J. McManus et al. JOURNAL OF NEUROSCIENCE
- Parkin Interacts with Ambra1 to Induce Mitophagy
- (2011) C. Van Humbeeck et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy
- (2011) Dao-Fu Dai et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Age-Associated Vascular Oxidative Stress, Nrf2 Dysfunction, and NF- B Activation in the Nonhuman Primate Macaca mulatta
- (2011) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes
- (2011) K. N. Papanicolaou et al. MOLECULAR AND CELLULAR BIOLOGY
- Caloric restriction
- (2011) John R. Speakman et al. MOLECULAR ASPECTS OF MEDICINE
- Image-based genome-wide siRNA screen identifies selective autophagy factors
- (2011) Anthony Orvedahl et al. NATURE
- Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging
- (2011) D. R. Green et al. SCIENCE
- Vascular Contributions to Cognitive Impairment and Dementia
- (2011) Philip B. Gorelick et al. STROKE
- AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction
- (2010) Subat Turdi et al. AGING CELL
- Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
- (2010) Dao-Fu Dai et al. AGING CELL
- Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
- (2010) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Development of Mitochondria-targeted Aromatic-cationic Peptides for Neurodegenerative Diseases
- (2010) Hazel H. Szeto Annals of the New York Academy of Sciences
- Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
- (2010) Raquel S. Carreira et al. Autophagy
- Inhibition of autophagy in the heart induces age-related cardiomyopathy
- (2010) Manabu Taneike et al. Autophagy
- What are the sources of hydrogen peroxide production by heart mitochondria?
- (2010) Vera G. Grivennikova et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Neuroprotective properties of resveratrol in different neurodegenerative disorders
- (2010) Diego Albani et al. BIOFACTORS
- Mitochondrial morphology and cardiovascular disease
- (2010) S.-B. Ong et al. CARDIOVASCULAR RESEARCH
- Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury
- (2010) Sang-Bing Ong et al. CIRCULATION
- Intramyocardial VEGF-B 167 Gene Delivery Delays the Progression Towards Congestive Failure in Dogs With Pacing-Induced Dilated Cardiomyopathy
- (2010) Martino Pepe et al. CIRCULATION RESEARCH
- Oxidative Stress and Endothelial Dysfunction in Cardiovascular Disease: Mitochondria-Targeted Therapeutics
- (2010) M. Rocha et al. CURRENT MEDICINAL CHEMISTRY
- Chaperone-mediated autophagy in protein quality control
- (2010) Esperanza Arias et al. CURRENT OPINION IN CELL BIOLOGY
- Arterial aging: a journey into subclinical arterial disease
- (2010) Mingyi Wang et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes
- (2010) A. Makino et al. DIABETOLOGIA
- Does calorie restriction induce mitochondrial biogenesis? A reevaluation
- (2010) Chad R. Hancock et al. FASEB JOURNAL
- Mitochondrial impairment contributes to cocaine-induced cardiac dysfunction: Prevention by the targeted antioxidant MitoQ
- (2010) Aurélia Vergeade et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging
- (2010) Ken Shinmura et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mitochondria and aging in the vascular system
- (2010) Zoltan Ungvari et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mechanisms of Vascular Aging: New Perspectives
- (2010) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Life-long caloric restriction elicits pronounced protection of the aged myocardium: A role for AMPK
- (2010) Andrew G. Edwards et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Cardiac Aging in Mice and Humans: The Role of Mitochondrial Oxidative Stress
- (2010) Dao-Fu Dai et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
- (2010) E Morselli et al. Cell Death & Disease
- Resveratrol induces mitochondrial biogenesis in endothelial cells
- (2009) Anna Csiszar et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial-derived hydrogen peroxide inhibits relaxation of bovine coronary arterial smooth muscle to hypoxia through stimulation of ERK MAP kinase
- (2009) Qun Gao et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells
- (2009) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging
- (2009) Mary L. Modrick et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- MitoQ administration prevents endotoxin-induced cardiac dysfunction
- (2009) G. S. Supinski et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial–Lysosomal Axis Theory of Aging
- (2009) Alexei Terman et al. ANTIOXIDANTS & REDOX SIGNALING
- Alzheimer Disease–Associated Peptide, Amyloid β40, Inhibits Vascular Regeneration With Induction of Endothelial Autophagy
- (2009) Shin-ichiro Hayashi et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Emerging roles of mitochondrial membrane dynamics in health and disease
- (2009) Anja Schäfer et al. BIOLOGICAL CHEMISTRY
- Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway
- (2009) Narasimman Gurusamy et al. CARDIOVASCULAR RESEARCH
- Mitochondrial OPA1, apoptosis, and heart failure
- (2009) Le Chen et al. CARDIOVASCULAR RESEARCH
- Role of BNIP3 and NIX in cell death, autophagy and mitophagy
- (2009) J Zhang et al. CELL DEATH AND DIFFERENTIATION
- Metformin Prevents Progression of Heart Failure in Dogs
- (2009) Hideyuki Sasaki et al. CIRCULATION
- Heart Disease and Stroke Statistics—2009 Update
- (2009) et al. CIRCULATION
- Suppression of Phosphoinositide 3-Kinase Prevents Cardiac Aging in Mice
- (2009) Yasutaka Inuzuka et al. CIRCULATION
- Overexpression of Catalase Targeted to Mitochondria Attenuates Murine Cardiac Aging
- (2009) Dao-Fu Dai et al. CIRCULATION
- Antioxidant, EUK-8, Prevents Murine Dilated Cardiomyopathy
- (2009) Satoru Kawakami et al. CIRCULATION JOURNAL
- Cellular Mechanisms of Cardioprotection by Calorie Restriction: State of the Science and Future Perspectives
- (2009) Emanuele Marzetti et al. CLINICS IN GERIATRIC MEDICINE
- Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer’s disease
- (2009) Magali Dumont et al. FASEB JOURNAL
- Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
- (2009) Delyth Graham et al. HYPERTENSION
- Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1
- (2009) Anna Csiszar et al. MECHANISMS OF AGEING AND DEVELOPMENT
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases
- (2009) Wolfgang Voos RESEARCH IN MICROBIOLOGY
- Resveratrol preserves cerebrovascular density and cognitive function in aging mice
- (2009) Charlotte Oomen Frontiers in Aging Neuroscience
- Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats
- (2008) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice
- (2008) Anna Csiszar et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Ultrastructure of the Mitochondrion and Its Bearing on Function and Bioenergetics
- (2008) Giovanni Benard et al. ANTIOXIDANTS & REDOX SIGNALING
- Studies of the human aortic intima by a direct quantitative assay of mutant alleles in the mitochondrial genome
- (2008) M. Sazonova et al. ATHEROSCLEROSIS
- Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
- (2008) Gilad Twig et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
- (2008) Tianzheng Yu et al. CARDIOVASCULAR RESEARCH
- Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
- (2008) Philip Wenzel et al. CARDIOVASCULAR RESEARCH
- Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
- (2008) Kevin J. Pearson et al. Cell Metabolism
- Antioxidant Gene Therapy for Cardiovascular Disease
- (2008) Anna-Liisa Levonen et al. CIRCULATION
- Mechanisms Underlying Caloric Restriction and Lifespan Regulation
- (2008) Zoltan Ungvari et al. CIRCULATION RESEARCH
- Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure
- (2008) Susheel Gundewar et al. CIRCULATION RESEARCH
- Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
- (2008) Gilad Twig et al. EMBO JOURNAL
- Low Doses of Insulin-Like Growth Factor-I Induce Mitochondrial Protection in Aging Rats
- (2008) Juan E. Puche et al. ENDOCRINOLOGY
- Mitochondrial biogenesis and healthy aging
- (2008) Guillermo López-Lluch et al. EXPERIMENTAL GERONTOLOGY
- Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart
- (2008) J.L. Barger et al. EXPERIMENTAL GERONTOLOGY
- The role of p66Shc deletion in age-associated arterial dysfunction and disease states
- (2008) Giovanni G. Camici et al. JOURNAL OF APPLIED PHYSIOLOGY
- Vascular endothelial senescence: from mechanisms to pathophysiology
- (2008) Jorge D. Erusalimsky JOURNAL OF APPLIED PHYSIOLOGY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Mitofusin 2 tethers endoplasmic reticulum to mitochondria
- (2008) Olga Martins de Brito et al. NATURE
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
- (2008) Jamie L. Barger et al. PLoS One
- Increased Aortic Calpain-1 Activity Mediates Age-Associated Angiotensin II Signaling of Vascular Smooth Muscle Cells
- (2008) Liqun Jiang et al. PLoS One
- Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury
- (2007) Hazel H. Szeto ANTIOXIDANTS & REDOX SIGNALING
- Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction
- (2007) Abdulrahman K. Doughan et al. CIRCULATION RESEARCH
- Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
- (2007) Andrew J. Farrall et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search