标题
Clinical epigenetics: seizing opportunities for translation
作者
关键词
-
出版物
NATURE REVIEWS GENETICS
Volume 20, Issue 2, Pages 109-127
出版商
Springer Nature
发表日期
2018-11-27
DOI
10.1038/s41576-018-0074-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Antiretroviral Therapy in Advanced HIV Disease: Which is the Best Regimen?
- (2018) Joaquim Burgos et al. AIDS REVIEWS
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
- (2018) Katherine A. Hoadley et al. CELL
- Human Papillomavirus DNA Methylation as a Biomarker for Cervical Precancer: Consistency across 12 Genotypes and Potential Impact on Management of HPV-Positive Women
- (2018) Megan A. Clarke et al. CLINICAL CANCER RESEARCH
- Optimal Management of Histone Deacetylase Inhibitor-Related Adverse Events in Patients With Multiple Myeloma: A Focus on Panobinostat
- (2018) Jamie D. Cavenagh et al. Clinical Lymphoma Myeloma & Leukemia
- dCas9: A Versatile Tool for Epigenome Editing
- (2018) Daan J.W. Brocken et al. CURRENT ISSUES IN MOLECULAR BIOLOGY
- Epigenetics of inflammatory arthritis
- (2018) Deepa Hammaker et al. CURRENT OPINION IN RHEUMATOLOGY
- DNA methylation-based classification of central nervous system tumours
- (2018) David Capper et al. NATURE
- PM20D1 is a quantitative trait locus associated with Alzheimer’s disease
- (2018) Jose V. Sanchez-Mut et al. NATURE MEDICINE
- Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin
- (2018) Manuel Rodríguez-Paredes et al. Nature Communications
- Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis
- (2018) Felix Bormann et al. Cell Reports
- Epigenetics and precision medicine in cardiovascular patients: from basic concepts to the clinical arena
- (2017) Sarah Costantino et al. EUROPEAN HEART JOURNAL
- Interleukin-2 receptor-α proximal promoter hypomethylation is associated with multiple sclerosis
- (2017) J Field et al. GENES AND IMMUNITY
- Maternal Macronutrient Consumption and the Developmental Origins of Metabolic Disease in the Offspring
- (2017) Stephanie Kereliuk et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetics of psoriatic disease: A systematic review and critical appraisal
- (2017) Remy A. Pollock et al. JOURNAL OF AUTOIMMUNITY
- Targeting noncoding RNAs in disease
- (2017) Brian D. Adams et al. JOURNAL OF CLINICAL INVESTIGATION
- Epi proColon® 2.0 CE: A Blood-Based Screening Test for Colorectal Cancer
- (2017) Yvette N. Lamb et al. Molecular Diagnosis & Therapy
- Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation
- (2017) Talal Jamil Qazi et al. MOLECULAR NEUROBIOLOGY
- α-Synuclein promotes dilation of the exocytotic fusion pore
- (2017) Todd Logan et al. NATURE NEUROSCIENCE
- The IBD interactome: an integrated view of aetiology, pathogenesis and therapy
- (2017) Heitor S. P. de Souza et al. Nature Reviews Gastroenterology & Hepatology
- Genetic insights into the neurodevelopmental origins of schizophrenia
- (2017) Rebecca Birnbaum et al. NATURE REVIEWS NEUROSCIENCE
- New insights into the epigenetics of inflammatory rheumatic diseases
- (2017) Esteban Ballestar et al. Nature Reviews Rheumatology
- The Epigenetics of Epilepsy and Its Progression
- (2017) Rebecca M. Hauser et al. NEUROSCIENTIST
- DNA methylation at the 9p21 glaucoma susceptibility locus is associated with normal-tension glaucoma
- (2017) Kathryn P. Burdon et al. OPHTHALMIC GENETICS
- Epigenetic research in multiple sclerosis: progress, challenges, and opportunities
- (2017) Galina Y. Zheleznyakova et al. PHYSIOLOGICAL GENOMICS
- Single-cell epigenomics: Recording the past and predicting the future
- (2017) Gavin Kelsey et al. SCIENCE
- Single-Cell Multiomics: Multiple Measurements from Single Cells
- (2017) Iain C. Macaulay et al. TRENDS IN GENETICS
- Epigenetic Alterations in Human Papillomavirus-Associated Cancers
- (2017) David Soto et al. Viruses-Basel
- Epigenetics and allergy: from basic mechanisms to clinical applications
- (2017) Daniel P Potaczek et al. Epigenomics
- The Epitranscriptome of Noncoding RNAs in Cancer
- (2017) Manel Esteller et al. Cancer Discovery
- Epigenetic Biomarkers for Parkinson’s Disease: From Diagnostics to Therapeutics
- (2017) Jennifer L. Jakubowski et al. Journal of Parkinsons Disease
- Translating epigenetics into clinic: focus on lupus
- (2017) Zijun Wang et al. Clinical Epigenetics
- Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
- (2017) Roberta Mazzone et al. Clinical Epigenetics
- Epigenetic mechanisms during ageing and neurogenesis as novel therapeutic avenues in human brain disorders
- (2017) Raúl Delgado-Morales et al. Clinical Epigenetics
- From genetics and epigenetics to the future of precision treatment for obesity
- (2017) Xulong Sun et al. Gastroenterology Report
- B Vitamin Deficiency Promotes Tau Phosphorylation Through Regulation of GSK3β and PP2A
- (2017) Vincenzina Nicolia et al. JOURNAL OF ALZHEIMERS DISEASE
- Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis
- (2017) Teresa Ayuso et al. PLoS One
- DNA Methylomes Reveal Biological Networks Involved in Human Eye Development, Functions and Associated Disorders
- (2017) María Berdasco et al. Scientific Reports
- Clinical and molecular analyses of Beckwith-Wiedemann syndrome: Comparison between spontaneous conception and assisted reproduction techniques
- (2016) Jair Tenorio et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Repetitive element hypermethylation in multiple sclerosis patients
- (2016) K. Y. Neven et al. BMC GENETICS
- Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes
- (2016) R. Guerrero-Preston et al. Cancer Prevention Research
- Combining Epigenetic and Immunotherapy to Combat Cancer
- (2016) Katherine B. Chiappinelli et al. CANCER RESEARCH
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery
- (2016) Hendrik G. Stunnenberg et al. CELL
- A Landscape of Pharmacogenomic Interactions in Cancer
- (2016) Francesco Iorio et al. CELL
- Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin
- (2016) Matthew W. Snyder et al. CELL
- Multitarget Drugs: an Epigenetic Epiphany
- (2016) A. Ganesan ChemMedChem
- Romidepsin for the treatment of relapsed/refractory cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome): Use in a community setting
- (2016) Sunil A. Reddy CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Histone modifying enzymes: novel disease biomarkers and assay development
- (2016) Fei Ma et al. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
- Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer
- (2016) Anna Martínez-Cardús et al. GASTROENTEROLOGY
- Time to take human embryo culture seriously: Table I
- (2016) Arne Sunde et al. HUMAN REPRODUCTION
- New Concepts in Cancer Biomarkers: Circulating miRNAs in Liquid Biopsies
- (2016) Erika Larrea et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer
- (2016) Petra ter Brugge et al. JNCI-Journal of the National Cancer Institute
- Gene promoter methylation and expression of Pin1 differ between patients with frontotemporal dementia and Alzheimer's disease
- (2016) Evelyn Ferri et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Evaluation of an Epigenetic Profile for the Detection of Bladder Cancer in Patients with Hematuria
- (2016) Kim E.M. van Kessel et al. JOURNAL OF UROLOGY
- Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
- (2016) Sebastian Moran et al. LANCET ONCOLOGY
- Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues
- (2016) Kimberly A. Krautkramer et al. MOLECULAR CELL
- Epigenome-wide association study of body mass index and the adverse outcomes of adiposity
- (2016) Simone Wahl et al. NATURE
- Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
- (2016) Christoph Bock et al. NATURE BIOTECHNOLOGY
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- Developing and evaluating polygenic risk prediction models for stratified disease prevention
- (2016) Nilanjan Chatterjee et al. NATURE REVIEWS GENETICS
- Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer
- (2016) Angel Diaz-Lagares et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of tissue-specific cell death using methylation patterns of circulating DNA
- (2016) Roni Lehmann-Werman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism
- (2016) Joseph B. Moore et al. STEM CELLS
- Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics
- (2016) Joanne Ryan et al. Epigenomics
- Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner
- (2016) David Cano-Rodriguez et al. Nature Communications
- The Impact of External Factors on the Epigenome:In Uteroand over Lifetime
- (2016) Estela G. Toraño et al. Biomed Research International
- A clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancers
- (2016) Jeannine Diesch et al. Clinical Epigenetics
- Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
- (2016) Ludovica Morera et al. Clinical Epigenetics
- Epigenetic polypharmacology: from combination therapy to multitargeted drugs
- (2016) Angel R. de Lera et al. Clinical Epigenetics
- Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer
- (2016) Petra ter Brugge et al. JNCI-Journal of the National Cancer Institute
- Global changes in DNA methylation in Alzheimer’s disease peripheral blood mononuclear cells
- (2015) Andrea Di Francesco et al. BRAIN BEHAVIOR AND IMMUNITY
- Clinical utility of RASSF1A methylation in human malignancies
- (2015) A M Grawenda et al. BRITISH JOURNAL OF CANCER
- DNA demethylation and invasive cancer: implications for therapeutics
- (2015) David Cheishvili et al. BRITISH JOURNAL OF PHARMACOLOGY
- A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC
- (2015) Helai P. Mohammad et al. CANCER CELL
- Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
- (2015) Kristian W. Pajtler et al. CANCER CELL
- Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer
- (2015) Noël J.-M. Raynal et al. CANCER RESEARCH
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Epigenetics and Primary Biliary Cirrhosis: a Comprehensive Review and Implications for Autoimmunity
- (2015) Yu-Qing Xie et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Histone Methylation Marks on Circulating Nucleosomes as Novel Blood-Based Biomarker in Colorectal Cancer
- (2015) Ugur Gezer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNA as Biomarkers and Diagnostics
- (2015) Jin Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Belinostat in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results of the Pivotal Phase II BELIEF (CLN-19) Study
- (2015) Owen A. O'Connor et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy of Tranylcypromine in Bipolar Depression
- (2015) Willemijn T. Heijnen et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat inEx VivoCultures of Resting CD4+T Cells
- (2015) Manoj K. Tripathy et al. JOURNAL OF VIROLOGY
- Valproic acid enhances neuronal differentiation of sympathoadrenal progenitor cells
- (2015) V Vukićević et al. MOLECULAR PSYCHIATRY
- An epigenome-wide association study of total serum immunoglobulin E concentration
- (2015) Liming Liang et al. NATURE
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
- (2015) Norihiro Kato et al. NATURE GENETICS
- The consensus molecular subtypes of colorectal cancer
- (2015) Justin Guinney et al. NATURE MEDICINE
- Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
- (2015) Pawel K Mazur et al. NATURE MEDICINE
- Amyotrophic lateral sclerosis: mechanisms and therapeutics in the epigenomic era
- (2015) Ximena Paez-Colasante et al. Nature Reviews Neurology
- Distinct promoter methylation and isoform-specific expression of RASFF1A in placental biopsies from complicated pregnancies
- (2015) I. Iglesias-Platas et al. PLACENTA
- Valproic acid-mediated neuroprotection and neurogenesis after spinal cord injury: from mechanism to clinical potential
- (2015) Tianci Chu et al. Regenerative Medicine
- Germline and Pluripotent Stem Cells
- (2015) Wolf Reik et al. Cold Spring Harbor Perspectives in Biology
- KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease
- (2015) Tamara Maes et al. Epigenomics
- Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs
- (2015) Vanesa Nogales et al. Oncotarget
- Epigenetic control of HIV-1 post integration latency: implications for therapy
- (2015) Amit Kumar et al. Clinical Epigenetics
- Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer
- (2015) Monika Bauden et al. Clinical Epigenetics
- Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases
- (2015) Bidisha Paul et al. Clinical Epigenetics
- Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis
- (2015) Adam P. Cribbs et al. Arthritis & Rheumatology
- Vorinostat-An overview
- (2015) AdityaKumar Bubna INDIAN JOURNAL OF DERMATOLOGY
- Reference-free cell mixture adjustments in analysis of DNA methylation data
- (2014) Eugene Andres Houseman et al. BIOINFORMATICS
- Diet, the Gut Microbiome, and Epigenetics
- (2014) Meredith A. J. Hullar et al. CANCER JOURNAL
- Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
- (2014) E. Nilsson et al. DIABETES
- Assisted reproductive technologies impair the expression and methylation of insulin-induced gene 1 and sterol regulatory element-binding factor 1 in the fetus and placenta
- (2014) Hangying Lou et al. FERTILITY AND STERILITY
- Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease
- (2014) Jose Vicente Sanchez-Mut et al. HIPPOCAMPUS
- Methylation marker analysis of self-sampled cervico-vaginal lavage specimens to triage high-risk HPV-positive women for colposcopy
- (2014) A.T. Hesselink et al. INTERNATIONAL JOURNAL OF CANCER
- New and emerging HDAC inhibitors for cancer treatment
- (2014) Alison C. West et al. JOURNAL OF CLINICAL INVESTIGATION
- Prolonged Administration of Azacitidine With or Without Entinostat for Myelodysplastic Syndrome and Acute Myeloid Leukemia With Myelodysplasia-Related Changes: Results of the US Leukemia Intergroup Trial E1905
- (2014) Thomas Prebet et al. JOURNAL OF CLINICAL ONCOLOGY
- Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
- (2014) Kai Wang et al. NATURE GENETICS
- Epigenome-wide association studies without the need for cell-type composition
- (2014) James Zou et al. NATURE METHODS
- Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
- (2014) Nitai C Hait et al. NATURE NEUROSCIENCE
- 'The clocks that time us'—circadian rhythms in neurodegenerative disorders
- (2014) Aleksandar Videnovic et al. Nature Reviews Neurology
- A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect
- (2014) Paula Lopez-Serra et al. Nature Communications
- Accounting for cellular heterogeneity is critical in epigenome-wide association studies
- (2014) Andrew E Jaffe et al. GENOME BIOLOGY
- Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
- (2014) Thomas A Rasmussen et al. Lancet HIV
- Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
- (2013) S. R. Daigle et al. BLOOD
- Histone H3.3 Mutations: A Variant Path to Cancer
- (2013) Benjamin T.K. Yuen et al. CANCER CELL
- Alterations in cardiac DNA methylation in human dilated cardiomyopathy
- (2013) Jan Haas et al. EMBO Molecular Medicine
- Prospective evaluation of methylatedSEPT9in plasma for detection of asymptomatic colorectal cancer
- (2013) Timothy Robert Church et al. GUT
- Genetic syndromes caused by mutations in epigenetic genes
- (2013) María Berdasco et al. HUMAN GENETICS
- Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation
- (2013) Atsushi Iwata et al. HUMAN MOLECULAR GENETICS
- The Role of FOXP3 in Regulating Immune Responses
- (2013) Jens Vent-Schmidt et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- Epigenetic Inactivation of the BRCA1 Interactor SRBC and Resistance to Oxaliplatin in Colorectal Cancer
- (2013) Catia Moutinho et al. JNCI-Journal of the National Cancer Institute
- Hypomethylation of SNCA in blood of patients with sporadic Parkinson's disease
- (2013) San-xi Ai et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
- (2013) Yun Liu et al. NATURE BIOTECHNOLOGY
- Global Epigenomic Reconfiguration During Mammalian Brain Development
- (2013) R. Lister et al. SCIENCE
- A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue
- (2013) Tina Rönn et al. PLoS Genetics
- Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
- (2013) Devin M. Absher et al. PLoS Genetics
- DNA Methylation Plasticity of Human Adipose-Derived Stem Cells in Lineage Commitment
- (2012) María Berdasco et al. AMERICAN JOURNAL OF PATHOLOGY
- Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
- (2012) Romain Barrès et al. Cell Metabolism
- Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes
- (2012) M. D. Nitert et al. DIABETES
- Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
- (2012) S. C. Jacobsen et al. DIABETOLOGIA
- DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients
- (2012) Michael Volkmar et al. EMBO JOURNAL
- Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study
- (2012) JP Routy et al. HIV MEDICINE
- Epigenetics and the adaptive immune response
- (2012) Hrisavgi D. Kondilis-Mangum et al. MOLECULAR ASPECTS OF MEDICINE
- Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
- (2012) N. M. Archin et al. NATURE
- DNA methylome analysis using short bisulfite sequencing data
- (2012) Felix Krueger et al. NATURE METHODS
- Epigenetic regulation of BACE1 in Alzheimer’s disease patients and in transgenic mice
- (2012) S.C.F. Marques et al. NEUROSCIENCE
- RNA modulation of the human DNA methyltransferase 3A
- (2012) Celeste Holz-Schietinger et al. NUCLEIC ACIDS RESEARCH
- Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
- (2011) Jelena Vojinovic et al. ARTHRITIS AND RHEUMATISM
- Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer
- (2011) Jorja D Warren et al. BMC Medicine
- A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity
- (2011) S-Y Lin et al. GENES AND IMMUNITY
- Epigenetic Control of the Host Gene by Commensal Bacteria in Large Intestinal Epithelial Cells
- (2011) Kyoko Takahashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions
- (2011) X. Pedre et al. JOURNAL OF NEUROSCIENCE
- Initial impact of the sequencing of the human genome
- (2011) Eric S. Lander NATURE
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- SMA CARNI-VAL TRIAL PART II: A Prospective, Single-Armed Trial of L-Carnitine and Valproic Acid in Ambulatory Children with Spinal Muscular Atrophy
- (2011) John T. Kissel et al. PLoS One
- Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer
- (2011) R. A. Juergens et al. Cancer Discovery
- Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production
- (2011) Sharon A. Chung et al. PLoS Genetics
- Vorinostat and Sorafenib Increase CD95 Activation in Gastrointestinal Tumor Cells through a Ca2+-De novo Ceramide-PP2A-Reactive Oxygen Species-Dependent Signaling Pathway
- (2010) M. A. Park et al. CANCER RESEARCH
- Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
- (2010) María Berdasco et al. DEVELOPMENTAL CELL
- Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes
- (2010) K.-M. Schmitz et al. GENES & DEVELOPMENT
- BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors
- (2010) Jurgen Veeck et al. JOURNAL OF CLINICAL ONCOLOGY
- Principles and challenges of genome-wide DNA methylation analysis
- (2010) Peter W. Laird NATURE REVIEWS GENETICS
- The specific role of histone deacetylase 2 in adult neurogenesis
- (2010) Melanie Jawerka et al. Neuron Glia Biology
- Clinical use of circulating nucleosomes
- (2009) Stefan Holdenrieder et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
- The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer
- (2009) A. F. Fernandez et al. GENOME RESEARCH
- Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
- (2009) B. M. Javierre et al. GENOME RESEARCH
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
- (2009) Daniel A. Lim et al. NATURE
- Epigenetic biomarker development
- (2009) Christoph Bock Epigenomics
- Phase 2 study of sodium phenylbutyrate in ALS
- (2008) Merit E. Cudkowicz et al. Amyotrophic Lateral Sclerosis
- Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
- (2008) T ABEL et al. CURRENT OPINION IN PHARMACOLOGY
- Persistent epigenetic differences associated with prenatal exposure to famine in humans
- (2008) B. T. Heijmans et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Biobanking: old activity or young discipline?
- (2008) Manuel M. Morente et al. SEMINARS IN DIAGNOSTIC PATHOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started