A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas

YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner

(2015) Dasol Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeted therapies for advanced Ewing sarcoma family of tumors

(2015) Yunyun Jiang et al.   CANCER TREATMENT REVIEWS

Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3-FOXO1-Positive Alveolar Rhabdomyosarcoma

(2015) J. J. G. Kephart et al.   CLINICAL CANCER RESEARCH

The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer

(2015) S. Song et al.   CLINICAL CANCER RESEARCH

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

(2015) E. Enzo et al.   EMBO JOURNAL

Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides

(2015) Zheng Zhou et al.   FASEB JOURNAL

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

(2015) Toshiro Moroishi et al.   GENES & DEVELOPMENT

Molecular characterization of epithelioid haemangioendotheliomas identifies novelWWTR1-CAMTA1fusion variants

(2015) Nimesh R Patel et al.   HISTOPATHOLOGY

AMPK modulates Hippo pathway activity to regulate energy homeostasis

(2015) Wenqi Wang et al.   NATURE CELL BIOLOGY

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

(2015) Luping Lin et al.   NATURE GENETICS

Hippo effector YAP1 inhibition—towards a new therapeutic option to overcome drug resistance

(2015) Alessia Errico   Nature Reviews Clinical Oncology

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

(2015) S Zhao et al.   ONCOGENE

Sarcomas

(2015) Josephine H. HaDuong et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis

(2015) T. S. Karin Eisinger-Mathason et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells

(2015) Upal Basu-Roy et al.   Nature Communications

Adhesion glycoprotein CD44 functions as an upstream regulator of a network connecting ERK, AKT and Hippo-YAP pathways in cancer progression

(2015) Shiyi Yu et al.   Oncotarget

Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1

(2015) Eleni M. Tomazou et al.   Cell Reports

mTORC2 Regulates Cardiac Response to Stress by Inhibiting MST1

(2015) Sebastiano Sciarretta et al.   Cell Reports

Clonality and Evolutionary History of Rhabdomyosarcoma

(2015) Li Chen et al.   PLoS Genetics

The Neurofibromatosis 2 Tumor Suppressor Gene Product, Merlin, Regulates Human Meningioma Cell Growth by Signaling through YAP

(2015) Katherine Striedinger et al.   NEOPLASIA

G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway

(2014) X. Zhou et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Novel TAZ modulators enhance myogenic differentiation and muscle regeneration

(2014) Gun Hwa Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sarcoma classification: An update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone

(2014) Leona A. Doyle   CANCER

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

(2014) Annie M. Tremblay et al.   CANCER CELL

Notch Activation as a Driver of Osteogenic Sarcoma

(2014) Jianning Tao et al.   CANCER CELL

A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

(2014) Shi Jiao et al.   CANCER CELL

Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex

(2014) Cordelia Rauskolb et al.   CELL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation

(2014) M R Byun et al.   CELL DEATH AND DIFFERENTIATION

Hippo Tips the TGF-β Scale in Favor of Pluripotency

(2014) Alan C. Mullen   Cell Stem Cell

CD44 acts through RhoA to regulate YAP signaling

(2014) Yuchen Zhang et al.   CELLULAR SIGNALLING

Novel insights into G protein and G protein-coupled receptor signaling in cancer

(2014) Morgan O’Hayre et al.   CURRENT OPINION IN CELL BIOLOGY

Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases

(2014) Uta Flucke et al.   Diagnostic Pathology

The RAS and YAP1 dance, who is leading?

(2014) V. Corbo et al.   EMBO JOURNAL

Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover

(2014) X. Hong et al.   EMBO JOURNAL

The Hippo signaling pathway in stem cell biology and cancer

(2014) J.-S. Mo et al.   EMBO REPORTS

The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation

(2014) Katarzyna Brodowska et al.   EXPERIMENTAL EYE RESEARCH

cAMP-specific phosphodiesterase inhibitors: promising drugs for inflammatory and neurological diseases

(2014) Ana Martinez et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

MEF2 Transcription Factors Regulate Distinct Gene Programs in Mammalian Skeletal Muscle Differentiation

(2014) Nelsa L. Estrella et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcriptional Regulators TAZ and YAP Direct Transforming Growth Factor β-induced Tumorigenic Phenotypes in Breast Cancer Cells

(2014) Samantha E. Hiemer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coupling of Hedgehog and Hippo pathways promotes stem cell maintenance by stimulating proliferation

(2014) Jianhua Huang et al.   JOURNAL OF CELL BIOLOGY

Identification, Mechanism of Action, and Antitumor Activity of a Small Molecule Inhibitor of Hippo, TGF- , and Wnt Signaling Pathways

(2014) D. Basu et al.   MOLECULAR CANCER THERAPEUTICS

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma

(2014) IOANNIS PANAGOPOULOS et al.   ONCOLOGY REPORTS

Knockdown of YAP1 inhibits the proliferation of osteosarcoma cells in vitro and in vivo

(2014) ZHI YANG et al.   ONCOLOGY REPORTS

RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling

(2014) XU-HUI ZHOU et al.   ONCOLOGY REPORTS

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

(2014) J. W. Haskins et al.   Science Signaling

Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma

(2014) W. Zhang et al.   Science Signaling

The Regulatory Landscape of Osteogenic Differentiation

(2014) Anne-Mari Håkelien et al.   STEM CELLS

Comprehensive Genomic Analysis of Rhabdomyosarcoma Reveals a Landscape of Alterations Affecting a Common Genetic Axis in Fusion-Positive and Fusion-Negative Tumors

(2014) J. F. Shern et al.   Cancer Discovery

Spindle Cell Rhabdomyosarcoma: A Brief Diagnostic Review and Differential Diagnosis

(2013) Sarah Jayne Carroll et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

FGF2 stimulates osteogenic differentiation through ERK induced TAZ expression

(2013) Mi Ran Byun et al.   BONE

CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation

(2013) S. Yang et al.   CANCER RESEARCH

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

Control of the Hippo Pathway by Set7-Dependent Methylation of Yap

(2013) Menno J. Oudhoff et al.   DEVELOPMENTAL CELL

MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

(2013) Yi Tang et al.   DEVELOPMENTAL CELL

Regulation of Hippo Signaling by EGFR-MAPK Signaling through Ajuba Family Proteins

(2013) B.V.V.G. Reddy et al.   DEVELOPMENTAL CELL

RASSF2methylation is a strong prognostic marker in younger age patients with Ewing sarcoma

(2013) Seley Gharanei et al.   Epigenetics

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

RecurrentNCOA2gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma

(2013) Juan Miguel Mosquera et al.   GENES CHROMOSOMES & CANCER

NovelYAP1-TFE3fusion defines a distinct subset of epithelioid hemangioendothelioma

(2013) Cristina R. Antonescu et al.   GENES CHROMOSOMES & CANCER

Alveolar rhabdomyosarcoma–associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

(2013) Lisa E.S. Crose et al.   JOURNAL OF CLINICAL INVESTIGATION

Defining the Protein–Protein Interaction Network of the Human Hippo Pathway

(2013) Wenqi Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway

(2013) Morvarid Mohseni et al.   NATURE CELL BIOLOGY

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression

(2013) L H Chan et al.   ONCOGENE

Osteoblast-Targeted Overexpression of TAZ Increases Bone Mass In Vivo

(2013) Jae-Yeon Yang et al.   PLoS One

Constitutive Expression of Yes-Associated Protein (Yap) in Adult Skeletal Muscle Fibres Induces Muscle Atrophy and Myopathy

(2013) Robert N. Judson et al.   PLoS One

Silencing of CD44 Gene Expression in Human 143-B Osteosarcoma Cells Promotes Metastasis of Intratibial Tumors in SCID Mice

(2013) Ana Gvozdenovic et al.   PLoS One

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo Signaling Pathway Interactome

(2013) Y. Kwon et al.   SCIENCE

Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions

(2013) A. L. Couzens et al.   Science Signaling

The p130 Isoform of Angiomotin Is Required for Yap-Mediated Hepatic Epithelial Cell Proliferation and Tumorigenesis

(2013) C. Yi et al.   Science Signaling

Ajuba Family Proteins Link JNK to Hippo Signaling

(2013) G. Sun et al.   Science Signaling

Regulation of the Hippo pathway and implications for anticancer drug development

(2013) Hyun Woo Park et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

SOX2 Regulates YAP1 to Maintain Stemness and Determine Cell Fate in the Osteo-Adipo Lineage

(2013) Eunjeong Seo et al.   Cell Reports

Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

(2013) Marcus Renner et al.   GENOME BIOLOGY

Notch signaling in pediatric soft tissue sarcomas

(2012) Rossella Rota et al.   BMC Medicine

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

(2012) Ryan B. Corcoran et al.   CANCER CELL

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

(2012) Eric Miller et al.   CHEMISTRY & BIOLOGY

Biomechanical regulation of mesenchymal cell function

(2012) Daniel J. Tschumperlin et al.   CURRENT OPINION IN RHEUMATOLOGY

Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice

(2012) Hoogeun Song et al.   EMBO JOURNAL

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

(2012) Suriyan Ponnusamy et al.   EMBO Molecular Medicine

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

(2012) J.-S. Mo et al.   GENES & DEVELOPMENT

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

(2012) B. Zhao et al.   GENES & DEVELOPMENT

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

(2012) R. N. Judson et al.   JOURNAL OF CELL SCIENCE

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

(2012) Miki Nishio et al.   JOURNAL OF CLINICAL INVESTIGATION

PAX3/FOXO1Fusion Gene Status Is the Key Prognostic Molecular Marker in Rhabdomyosarcoma and Significantly Improves Current Risk Stratification

(2012) Edoardo Missiaglia et al.   JOURNAL OF CLINICAL ONCOLOGY

Vestigial-like 3 is an inhibitor of adipocyte differentiation

(2012) Daniel S. Halperin et al.   JOURNAL OF LIPID RESEARCH

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals

(2012) S Moleirinho et al.   ONCOGENE

Children's Oncology Group's 2013 blueprint for research: Bone tumors

(2012) Richard Gorlick et al.   PEDIATRIC BLOOD & CANCER

Children's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas

(2012) Douglas S. Hawkins et al.   PEDIATRIC BLOOD & CANCER

Mammalian Ste20-Like Kinase and SAV1 Promote 3T3-L1 Adipocyte Differentiation by Activation of PPARγ

(2012) Byoung Hee Park et al.   PLoS One

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of the Hippo pathway by cell architecture and mechanical signals

(2012) Molly C. Schroeder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Integration of intercellular signaling through the Hippo pathway

(2012) Kenneth D. Irvine   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer

(2012) A M Richter et al.   Oncogenesis

Effects of mTOR Inhibitors on Components of the Salvador-Warts-Hippo Pathway

(2012) Jonathan Chiang et al.   Cells

TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

(2011) EJ Jang et al.   BRITISH JOURNAL OF PHARMACOLOGY

MOB control: Reviewing a conserved family of kinase regulators

(2011) Alexander Hergovich   CELLULAR SIGNALLING

Inhibition of the Notch-Hey1 Axis Blocks Embryonal Rhabdomyosarcoma Tumorigenesis

(2011) B. C. Belyea et al.   CLINICAL CANCER RESEARCH

FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools

(2011) N. J. Van Hateren et al.   DEVELOPMENT

Hippo pathway regulation by cell morphology and stress fibers

(2011) K.-I. Wada et al.   DEVELOPMENT

The Sterile 20-like Kinase Tao-1 Controls Tissue Growth by Regulating the Salvador-Warts-Hippo Pathway

(2011) Carole L.C. Poon et al.   DEVELOPMENTAL CELL

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

(2011) Leticia Sansores-Garcia et al.   EMBO JOURNAL

A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites

(2011) Costantino Errani et al.   GENES CHROMOSOMES & CANCER

Mammalian Hippo pathway: from development to cancer and beyond

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

Hippo signaling: A hub of growth control, tumor suppression and pluripotency maintenance

(2011) Mengxin Yin et al.   Journal of Genetics and Genomics

Biochemical and Structural Characterization of Lysophosphatidic Acid Binding by a Humanized Monoclonal Antibody

(2011) Jonathan K. Fleming et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Integrating developmental signals: a Hippo in the (path)way

(2011) A Mauviel et al.   ONCOGENE

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma

(2011) M. R. Tanas et al.   Science Translational Medicine

14-3-3 proteins as potential therapeutic targets

(2011) Jing Zhao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Yap is a novel regulator of C2C12 myogenesis

(2010) Kevin I. Watt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts

(2010) Hichame Id Boufker et al.   BMC CANCER

Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

(2010) Binnaz Kucuk Staley et al.   CURRENT BIOLOGY

Upstream Regulation of the Hippo Size Control Pathway

(2010) Felix A. Grusche et al.   CURRENT BIOLOGY

The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

(2010) P. Karpowicz et al.   DEVELOPMENT

Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors

(2010) Gongping Sun et al.   DEVELOPMENTAL BIOLOGY

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

The WW Domain Protein Kibra Acts Upstream of Hippo in Drosophila

(2010) Roland Baumgartner et al.   DEVELOPMENTAL CELL

Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded

(2010) Jianzhong Yu et al.   DEVELOPMENTAL CELL

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network

(2010) Alice Genevet et al.   DEVELOPMENTAL CELL

TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

(2010) Hana Jeong et al.   FASEB JOURNAL

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

(2010) J. Cai et al.   GENES & DEVELOPMENT

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

(2010) I. Lian et al.   GENES & DEVELOPMENT

YAP1 and VGLL3, encoding two cofactors of TEAD transcription factors, are amplified and overexpressed in a subset of soft tissue sarcomas

(2010) Zofia Hélias-Rodzewicz et al.   GENES CHROMOSOMES & CANCER

Tumor Suppressor Ras Association Domain Family 5 (RASSF5/NORE1) Mediates Death Receptor Ligand-induced Apoptosis

(2010) Jikyoung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Expression Profiling for Survival Prediction in Pediatric Rhabdomyosarcomas: A Report From the Children's Oncology Group

(2010) Elai Davicioni et al.   JOURNAL OF CLINICAL ONCOLOGY

Fusion Gene–Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma

(2010) Daniel Williamson et al.   JOURNAL OF CLINICAL ONCOLOGY

BMI-1 suppresses contact inhibition and stabilizes YAP in Ewing sarcoma

(2010) J H Hsu et al.   ONCOGENE

Integrins and Extracellular Matrix in Mechanotransduction

(2010) M. A. Schwartz   Cold Spring Harbor Perspectives in Biology

Augmentation of PPARγ-TAZ interaction contributes to the anti-adipogenic activity of KR62980

(2009) Hana Jung et al.   BIOCHEMICAL PHARMACOLOGY

Both TEAD-Binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-Associated Protein

(2009) B. Zhao et al.   CANCER RESEARCH

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

Cytoskeletal control of growth and cell fate switching

(2009) Akiko Mammoto et al.   CURRENT OPINION IN CELL BIOLOGY

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

(2009) A. Fernandez-L et al.   GENES & DEVELOPMENT

Identification of interactive networks of gene expression associated with osteosarcoma oncogenesis by integrated molecular profiling

(2009) Bekim Sadikovic et al.   HUMAN MOLECULAR GENETICS

TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation

(2009) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hippo pathway regulates apical-domain size independently of its growth-control function

(2009) A. Genevet et al.   JOURNAL OF CELL SCIENCE

Toward the Development of a Potent and Selective Organoruthenium Mammalian Sterile 20 Kinase Inhibitor

(2009) Ruchi Anand et al.   JOURNAL OF MEDICINAL CHEMISTRY

Two genetic pathways, t(1;10) and amplification of 3p11-12, in myxoinflammatory fibroblastic sarcoma, haemosiderotic fibrolipomatous tumour, and morphologically similar lesions

(2009) Karolin H Hallor et al.   JOURNAL OF PATHOLOGY

Structure-Activity Relationship Studies of Fostriecin, Cytostatin, and Key Analogs, with PP1, PP2A, PP5, and ( 12- 13)-Chimeras (PP1/PP2A and PP5/PP2A), Provide Further Insight into the Inhibitory Actions of Fostriecin Family Inhibitors

(2009) M. R. Swingle et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Targeting Protein Serine/Threonine Phosphatases for Drug Development

(2009) J. L. McConnell et al.   MOLECULAR PHARMACOLOGY

Aberrant methylation and reduced expression ofRASSF1Ain Ewing sarcoma

(2009) Smadar Avigad et al.   PEDIATRIC BLOOD & CANCER

The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen

(2009) J. M. Wojciak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

The Emerging Role of the Hippo Pathway in Cell Contact Inhibition, Organ Size Control, and Cancer Development in Mammals

(2008) Qi Zeng et al.   CANCER CELL

BMI-1 Promotes Ewing Sarcoma Tumorigenicity Independent of CDKN2A Repression

(2008) D. Douglas et al.   CANCER RESEARCH

YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation

(2008) Toshihiko Yokoyama et al.   CARCINOGENESIS

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

(2008) Andrew S. Brack et al.   Cell Stem Cell

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Prognostic Factors in Metastatic Rhabdomyosarcomas: Results of a Pooled Analysis From United States and European Cooperative Groups

(2008) Odile Oberlin et al.   JOURNAL OF CLINICAL ONCOLOGY

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

(2008) Xaralabos Varelas et al.   NATURE CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Hippo Pathway Promotes Notch Signaling in Regulation of Cell Differentiation, Proliferation, and Oocyte Polarity

(2008) Jianzhong Yu et al.   PLoS One

Pediatric Soft Tissue Sarcomas

(2008) David M. Loeb et al.   SURGICAL CLINICS OF NORTH AMERICA

MCAT Elements and the TEF-1 Family of Transcription Factors in Muscle Development and Disease

(2007) Tadashi Yoshida   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY