Switching the Sphingolipid Rheostat in the Treatment of Diabetes and Cancer Comorbidity from a Problem to an Advantage
出版年份 2015 全文链接
标题
Switching the Sphingolipid Rheostat in the Treatment of Diabetes and Cancer Comorbidity from a Problem to an Advantage
作者
关键词
-
出版物
Biomed Research International
Volume 2015, Issue -, Pages 1-9
出版商
Hindawi Limited
发表日期
2015-03-20
DOI
10.1155/2015/165105
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Selective inhibition of sphingosine kinase-1 protects adipose tissue against LPS-induced inflammatory response in Zucker diabetic fatty rats
- (2014) Monica Tous et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance
- (2014) Jing Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Vascular oxidative stress, nitric oxide and atherosclerosis
- (2014) Huige Li et al. ATHEROSCLEROSIS
- Evolving concepts in cancer therapy through targeting sphingolipid metabolism
- (2014) Jean-Philip Truman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro
- (2014) Giulia Marvaso et al. CANCER BIOLOGY & THERAPY
- Divergent Role of Sphingosine 1-Phosphate on Insulin Resistance
- (2014) Susann Fayyaz et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Insulin Resistance, Diabetes, and Cardiovascular Risk
- (2014) Francesco Paneni et al. Current Atherosclerosis Reports
- Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats
- (2014) Hongyang Yu et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1
- (2014) Kali Janes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An update on the biology of sphingosine 1-phosphate receptors
- (2014) Victoria A. Blaho et al. JOURNAL OF LIPID RESEARCH
- Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia
- (2014) R Mani et al. LEUKEMIA
- PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
- (2014) Martina SJ McDermott et al. Molecular Cancer
- PP2A Inhibition Is a Common Event in Colorectal Cancer and Its Restoration Using FTY720 Shows Promising Therapeutic Potential
- (2014) I. Cristobal et al. MOLECULAR CANCER THERAPEUTICS
- Sphingosine Kinase 1 Isoform-Specific Interactions in Breast Cancer
- (2014) Daniel Yagoub et al. MOLECULAR ENDOCRINOLOGY
- Cancer risks from diabetes therapies: Evaluating the evidence
- (2014) Chen Li et al. PHARMACOLOGY & THERAPEUTICS
- Cancer biology in diabetes
- (2014) Shi Sen et al. Journal of Diabetes Investigation
- Deregulation of the phosphatase, PP2A is a common event in breast cancer, predicting sensitivity to FTY720
- (2014) Shawn Baldacchino et al. EPMA Journal
- Second generation S1P pathway modulators: Research strategies and clinical developments
- (2013) Marc Bigaud et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Overexpression of the pp32r1 (ANP32C) oncogene or its functional mutant pp32r1Y140H confers enhanced resistance to FTY720 (Finguimod)
- (2013) Salma Buddaseth et al. CANCER BIOLOGY & THERAPY
- Type 1 diabetes and cardiovascular disease
- (2013) Oliver Schnell et al. Cardiovascular Diabetology
- Sphingosine 1-phosphate signalling
- (2013) K. Mendelson et al. DEVELOPMENT
- Diabetes and cancer: two diseases with obesity as a common risk factor
- (2013) S. K. Garg et al. DIABETES OBESITY & METABOLISM
- Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype
- (2013) Susann Fayyaz et al. DIABETOLOGIA
- Signaling Molecules Involved in Lipid-Induced Pancreatic Beta-Cell Dysfunction
- (2013) Shiying Shao et al. DNA AND CELL BIOLOGY
- Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I
- (2013) Francesco Paneni et al. EUROPEAN HEART JOURNAL
- Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic β-cell death in diet-induced obese mice
- (2013) Yanfei Qi et al. FASEB JOURNAL
- A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis
- (2013) Hazem J. Abuhusain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasma Sphingosine-1-Phosphate Is Elevated in Obesity
- (2013) Greg M. Kowalski et al. PLoS One
- Latest insights into the risk of cancer in diabetes
- (2013) Hiroshi Noto et al. Journal of Diabetes Investigation
- Sphingosine 1-phosphate signalling in cancer
- (2012) Nigel J. Pyne et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Sphingosine kinase and sphingosine 1-phosphate in the heart: A decade of progress
- (2012) Joel S. Karliner BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: Review of sphingosine kinase inhibitors
- (2012) K. Alexa Orr Gandy et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
- (2012) Jie Liang et al. CANCER CELL
- Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet-Fed Mice
- (2012) C. R. Bruce et al. DIABETES
- FTY720 preserved isletβ-cell mass by inhibiting apoptosis and increasing survival ofβ-cells in db/db mice
- (2012) Hosik Moon et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- The Sphingosine-1-Phosphate Analog FTY720 Reduces Muscle Ceramide Content and Improves Glucose Tolerance in High Fat-Fed Male Mice
- (2012) Clinton R. Bruce et al. ENDOCRINOLOGY
- Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model
- (2012) Myung-Hee Moon et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Effect of sphingosine kinase 1 inhibition on blood pressure
- (2012) Hideki Furuya et al. FASEB JOURNAL
- Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: Functional differences between sphingosine kinase 1a and 1b
- (2012) Keng Gat Lim et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Global estimates of cancer prevalence for 27 sites in the adult population in 2008
- (2012) Freddie Bray et al. INTERNATIONAL JOURNAL OF CANCER
- FTY720 Protects Cardiac Microvessels of Diabetes: A Critical Role of S1P1/3 in Diabetic Heart Disease
- (2012) Zhiyong Yin et al. PLoS One
- The Sphingolipid Rheostat: A Potential Target for Improving Pancreatic Islet Survival and Function
- (2012) Claire F. Jessup et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line
- (2011) N.M. Hasan et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
- (2011) Goodarz Danaei et al. LANCET
- Sphingosine Kinase-1 Pathway Mediates High Glucose-Induced Fibronectin Expression in Glomerular Mesangial Cells
- (2011) Tian Lan et al. MOLECULAR ENDOCRINOLOGY
- Sphingosine Kinase 1 Regulates the Akt/FOXO3a/Bim Pathway and Contributes to Apoptosis Resistance in Glioma Cells
- (2011) Hongyu Guan et al. PLoS One
- Sphingosine-1-phosphate signaling and its role in disease
- (2011) Michael Maceyka et al. TRENDS IN CELL BIOLOGY
- FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy
- (2010) Ning Zhang et al. Autophagy
- Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic β-cells
- (2010) Toshiyuki Imasawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sphingosine-1-phosphate antibodies as potential agents in the treatment of cancer and age-related macular degeneration
- (2010) Roger A. Sabbadini BRITISH JOURNAL OF PHARMACOLOGY
- Diabetes and Cancer: A consensus report
- (2010) E. Giovannucci et al. DIABETES CARE
- Insulin, glucose and the increased risk of cancer in patients with type 2 diabetes
- (2010) J. A. Johnson et al. DIABETOLOGIA
- Metformin: Taking away the candy for cancer?
- (2010) Mathilde Jalving et al. EUROPEAN JOURNAL OF CANCER
- Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
- (2010) William L Holland et al. NATURE MEDICINE
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sphingosine Protects Aging Hearts from Ischemia/Reperfusion Injury: Superiority to Sphingosine 1-Phosphate and Ischemic Pre- and Post-Conditioning
- (2010) Donald A. Vessey et al. Oxidative Medicine and Cellular Longevity
- Sphingosine 1-phosphate increases glucose uptake through trans-activation of insulin receptor
- (2009) Elena Rapizzi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Residual microvascular risk in diabetes: unmet needs and future directions
- (2009) Paola Fioretto et al. Nature Reviews Endocrinology
- Monocyte-Endothelial Cell Interactions in the Development of Atherosclerosis
- (2009) Javier Mestas et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3
- (2008) Angela M. Whetzel et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- New players on the center stage: Sphingosine 1-phosphate and its receptors as drug targets
- (2008) Andrea Huwiler et al. BIOCHEMICAL PHARMACOLOGY
- Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation
- (2008) C. S. Bonder et al. BLOOD
- Sphingosine kinase regulation and cardioprotection
- (2008) J. S. Karliner CARDIOVASCULAR RESEARCH
- Ischaemic postconditioning protects isolated mouse hearts against ischaemia/reperfusion injury via sphingosine kinase isoform-1 activation
- (2008) Z.-Q. Jin et al. CARDIOVASCULAR RESEARCH
- Long-term All-Cause Mortality in Cancer Patients With Preexisting Diabetes Mellitus
- (2008) Bethany B. Barone JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization
- (2008) Bing Xie et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Sphingosine 1-Phosphate Restrains Insulin-Mediated Keratinocyte Proliferation via Inhibition of Akt through the S1P2 Receptor Subtype
- (2008) Melanie Schüppel et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Type 2 Diabetes Mellitus and Skeletal Muscle Metabolic Function
- (2008) Esther Phielix et al. PHYSIOLOGY & BEHAVIOR
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