标题
Molecular Biology of Atherosclerosis
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 93, Issue 3, Pages 1317-1542
出版商
American Physiological Society
发表日期
2013-07-30
DOI
10.1152/physrev.00004.2012
参考文献
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- Hemodynamic Activation of β-Catenin and T-Cell-Specific Transcription Factor Signaling in Vascular Endothelium Regulates Fibronectin Expression
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- Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages
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- SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN Is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation
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- Deficient p27 Phosphorylation at Serine 10 Increases Macrophage Foam Cell Formation and Aggravates Atherosclerosis Through a Proliferation-Independent Mechanism
- (2011) José J. Fuster et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-γ–Regulated Genes
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- Activation of the Annexin A1 Pathway Underlies the Protective Effects Exerted by Estrogen in Polymorphonuclear Leukocytes
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- Impairment of the Programmed Cell Death-1 Pathway Increases Atherosclerotic Lesion Development and Inflammation
- (2011) De-xiu Bu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- CCL20 Is Increased in Hypercholesterolemic Subjects and Is Upregulated By LDL in Vascular Smooth Muscle Cells
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- Gain and Loss of Function for Glutathione Synthesis
- (2011) Andrea Callegari et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Cdkn2a Is an Atherosclerosis Modifier Locus That Regulates Monocyte/Macrophage Proliferation
- (2011) Chao-Ling Kuo et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Endoplasmic Reticulum Stress and Glycogen Synthase Kinase-3β Activation in Apolipoprotein E–Deficient Mouse Models of Accelerated Atherosclerosis
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- Overexpression of Tissue Inhibitor of Metalloproteinase 3 in Macrophages Reduces Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice
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- Transsignaling of Interleukin-6 Crucially Contributes to Atherosclerosis in Mice
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- Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and Atherosclerosis Development
- (2011) Akifumi Kushiyama et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- G Protein–Coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-Transmembrane Receptors
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- Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis
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- Interleukin-17A Deficiency Accelerates Unstable Atherosclerotic Plaque Formation in Apolipoprotein E-Deficient Mice
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- Accelerated Atherosclerosis in Apoe −/− Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1
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- The role of nicotine in the pathogenesis of atherosclerosis
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- Influence of pericoronary adipose tissue on local coronary atherosclerosis as assessed by a novel MDCT volumetric method
- (2011) Pál Maurovich-Horvat et al. ATHEROSCLEROSIS
- Glucosamine-supplementation promotes endoplasmic reticulum stress, hepatic steatosis and accelerated atherogenesis in apoE−/− mice
- (2011) Daniel R. Beriault et al. ATHEROSCLEROSIS
- Role for Nox1 NADPH oxidase in atherosclerosis
- (2011) Andrea L. Sheehan et al. ATHEROSCLEROSIS
- FoxO4 inhibits atherosclerosis through its function in bone marrow derived cells
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- Regulatory effects of sulfur dioxide on the development of atherosclerotic lesions and vascular hydrogen sulfide in atherosclerotic rats
- (2011) Wei Li et al. ATHEROSCLEROSIS
- TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice
- (2011) Victoria Watt et al. ATHEROSCLEROSIS
- Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice
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- Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms
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- P-selectin glycoprotein ligand-1 deficiency leads to cytokine resistance and protection against atherosclerosis in apolipoprotein E deficient mice
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- Increased atherosclerosis and vascular smooth muscle cell activation in AIF-1 transgenic mice fed a high-fat diet
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- Emerging role of high density lipoproteins as a player in the immune system
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- Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice
- (2011) Man C. Wong et al. ATHEROSCLEROSIS
- Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B
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- Arterial flow reduces oxidative stress via an antioxidant response element and Oct-1 binding site within the NADPH oxidase 4 promoter in endothelial cells
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- Global functional knockdown of ATP binding cassette transporter A1 stimulates development of atherosclerosis in apoE K/O mice
- (2011) Nigora Mukhamedova et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2011) Gabrielle Fredman et al. BIOCHEMICAL JOURNAL
- Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice
- (2011) Prakash G. Chandak et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Regulation of ABCA1 functions by signaling pathways
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- ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice
- (2011) C. Gandhi et al. BLOOD
- Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling
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- Hepcidin and iron regulation, 10 years later
- (2011) T. Ganz BLOOD
- Decreased production of neuronal NOS-derived hydrogen peroxide contributes to endothelial dysfunction in atherosclerosis
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- Specific loss of Toll-like receptor 2 on bone marrow derived cells decreases atherosclerosis in LDL receptor null mice*The senior author, Stewart C. Whitman, passed away on 19 February 2010. The manuscript has been communicated by Ross W. Milne (e-mail: rmilne@ottawaheart.ca) and Yves L. Marcel (e-mail: ylmarcel@ottawaheart.ca), University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada.
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- Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1
- (2011) L.-C. Ching et al. CARDIOVASCULAR RESEARCH
- Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis
- (2011) B. Zhou et al. CARDIOVASCULAR RESEARCH
- Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis
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- VEGF increases the proliferative capacity and eNOS/NO levels of endothelial progenitor cells through the calcineurin/NFAT signalling pathway
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- Resolvins and Protectins in Inflammation Resolution
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- (2011) Daniel F.J. Ketelhuth et al. CIRCULATION
- What Fans the Fire
- (2011) Amy S. Major et al. CIRCULATION
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- Network for Activation of Human Endothelial Cells by Oxidized Phospholipids
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- Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition
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- Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis
- (2011) Anouk A.J. Hamers et al. CIRCULATION RESEARCH
- B-Cell Aortic Homing and Atheroprotection Depend on Id3
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- Incremental Prognostic Value of Cardiac Computed Tomography in Coronary Artery Disease Using CONFIRM
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- Role of Age, Sex, and Race on Cardiac and Total Mortality Associated With Super Bowl Wins and Losses
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- HDL Measures, Particle Heterogeneity, Proposed Nomenclature, and Relation to Atherosclerotic Cardiovascular Events
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- Mannan-binding lectin deficiency — Good news, bad news, doesn't matter?
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- Multiple roles of angiopoietins in atherogenesis
- (2011) Asif Ahmed et al. CURRENT OPINION IN LIPIDOLOGY
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- (2011) Howard S. Kruth CURRENT OPINION IN LIPIDOLOGY
- Phenotypic modulation of macrophages in response to plaque lipids
- (2011) Samantha Adamson et al. CURRENT OPINION IN LIPIDOLOGY
- Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis
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- Signaling pathways for the vascular effects of hydrogen sulfide
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- Sirtuin 1-Mediated Cellular Metabolic Memory of High Glucose Via the LKB1/AMPK/ROS Pathway and Therapeutic Effects of Metformin
- (2011) Z. Zheng et al. DIABETES
- Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice
- (2011) M. Nagashima et al. DIABETOLOGIA
- Anti-Apolipoprotein A-1 auto-antibodies are active mediators of atherosclerotic plaque vulnerability
- (2011) Fabrizio Montecucco et al. EUROPEAN HEART JOURNAL
- The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
- (2011) Nehal N. Mehta et al. EUROPEAN HEART JOURNAL
- The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis
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- Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis
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- Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis
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- 5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion
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- Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy
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- Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years
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- Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response
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- The role of LKB1 and AMPK in cellular responses to stress and damage
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- Beyond ATM: The protein kinase landscape of the DNA damage response
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- Febuxostat inhibition of endothelial-bound XO: Implications for targeting vascular ROS production
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- Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression
- (2011) L. T. MacNeil et al. GENOME RESEARCH
- Iron sensing and signalling
- (2011) Rayko Evstatiev et al. GUT
- Endothelium-Dependent Contractions in Hypertension
- (2011) Paul M. Vanhoutte HYPERTENSION
- Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
- (2011) Jae-Hoon Choi et al. IMMUNITY
- Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production
- (2011) Shitao Li et al. IMMUNITY
- Association of Episodic Physical and Sexual Activity With Triggering of Acute Cardiac Events
- (2011) Issa J. Dahabreh JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Apolipoprotein CIII Links Dyslipidemia with Atherosclerosis
- (2011) Akio Kawakami et al. Journal of Atherosclerosis and Thrombosis
- Absence of Microbiota (Germ-Free Conditions) Accelerates the Atherosclerosis in ApoE-Deficient Mice Fed Standard Low Cholesterol Diet
- (2011) Renata Stepankova et al. Journal of Atherosclerosis and Thrombosis
- Loss of Clusterin Limits Atherosclerosis in Apolipoprotein E-deficient Mice via Reduced Expression of Egr-1 and TNF-α
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- Production of H2S by 3-mercaptopyruvate sulphurtransferase
- (2011) K. Tanizawa JOURNAL OF BIOCHEMISTRY
- Endoplasmic Reticulum Ca2+Release Modulates Endothelial Nitric-oxide Synthase via Extracellular Signal-regulated Kinase (ERK) 1/2-mediated Serine 635 Phosphorylation
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- Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α
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- Tristetraprolin-dependent Post-transcriptional Regulation of Inflammatory Cytokine mRNA Expression by Apolipoprotein A-I
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- Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin
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- Galectin-9 Protein Expression in Endothelial Cells Is Positively Regulated by Histone Deacetylase 3
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- Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid
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- Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress–specific manner
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- Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells
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- ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice
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- Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe–/– mice during disease regression
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- Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis
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- FOXO3 Deficiency Leads to Increased Susceptibility to Cigarette Smoke-Induced Inflammation, Airspace Enlargement, and Chronic Obstructive Pulmonary Disease
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- (2009) Caroline Cheng et al. CIRCULATION
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- Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and Atherosclerosis
- (2009) Giuseppe Danilo Norata et al. CIRCULATION
- Endothelial Estrogen Receptor-α Plays a Crucial Role in the Atheroprotective Action of 17β-Estradiol in Low-Density Lipoprotein Receptor–Deficient Mice
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- Toll-Like Receptor-2 Mediates Inflammation and Matrix Degradation in Human Atherosclerosis
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- Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow
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- Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex
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- Mediation of Electronegative Low-Density Lipoprotein Signaling by LOX-1
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- The Antiangiogenic Activity of rPAI-1 23 Inhibits Vasa Vasorum and Growth of Atherosclerotic Plaque
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- The Subendothelial Extracellular Matrix Modulates JNK Activation by Flow
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- Human Paraoxonase Gene Cluster Transgenic Overexpression Represses Atherogenesis and Promotes Atherosclerotic Plaque Stability in ApoE-Null Mice
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- Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells
- (2009) Bhama Ramkhelawon et al. CIRCULATION RESEARCH
- Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure
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- Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis
- (2009) Mete Civelek et al. CIRCULATION RESEARCH
- Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice
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- Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes
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