High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

Urea cycle regulation by mitochondrial sirtuin, SIRT5

(2016) Takashi Nakagawa et al.   Aging-US

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress

(2016) Ozkan Ozden et al.   Aging-US

Preventive effects of North American ginseng (Panax quinquefolium) on diabetic nephropathy

(2012) Subhrojit Sen et al.   PHYTOMEDICINE

Regulation of FoxO transcription factors by acetylation and protein–protein interactions

(2011) Hiroaki Daitoku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The PKB/FOXO switch in aging and cancer

(2011) David E.A. Kloet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

Transcriptional regulation of antioxidant enzymes by FoxO1 under dehydration stress

(2011) Amal Idris Malik et al.   GENE

Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription

(2011) Ramkumar Rajendran et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Dose-Dependent Modulatory Effects of Insulin on Glucose-Induced Endothelial Senescence In Vitro and In Vivo: A Relationship between Telomeres and Nitric Oxide

(2011) H. Matsui-Hirai et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Glucose-induced endothelin-1 expression is regulated by ERK5 in the endothelial cells and retina of diabetic ratsThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.

(2010) Yuexiu Wu et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

FoxO1: A molecule for all seasons

(2010) Stavroula Kousteni   JOURNAL OF BONE AND MINERAL RESEARCH

Microvascular changes in estrogen-α sensitive brainstem structures of aging female hamsters

(2010) Peter O. Gerrits et al.   NEUROSCIENCE RESEARCH

SIRT1 is regulated by a PPARγ–SIRT1 negative feedback loop associated with senescence

(2010) Limin Han et al.   NUCLEIC ACIDS RESEARCH

Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

(2009) Miguel A. Gama Sosa et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional coactivator p300 regulates glucose-induced gene expression in endothelial cells

(2009) Shali Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Lifestyle Risk Factors and New-Onset Diabetes Mellitus in Older Adults

(2009) Dariush Mozaffarian et al.   ARCHIVES OF INTERNAL MEDICINE

Impairedin vivovasculogenic potential of endothelial progenitor cells in comparison to human umbilical vein endothelial cells in a spheroid-based implantation model

(2009) G. Finkenzeller et al.   CELL PROLIFERATION

The mitochondrial theory of aging: Insight from transgenic and knockout mouse models

(2009) Youngmok C. Jang et al.   EXPERIMENTAL GERONTOLOGY

JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity

(2009) Nargis Nasrin et al.   PLoS One

Biological and Potential Therapeutic Roles of Sirtuin Deacetylases

(2008) D. M. Taylor et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

FOXOs, cancer and regulation of apoptosis

(2008) Z Fu et al.   ONCOGENE

Caloric Restriction and Aging: Studies in Mice and Monkeys

(2008) Rozalyn M. Anderson et al.   TOXICOLOGIC PATHOLOGY