An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes

(2013) Allison B. Goldfine   ANNALS OF INTERNAL MEDICINE

Insulin Resistance in the Defense against Obesity

(2012) Alan R. Saltiel   Cell Metabolism

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

(2012) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

Novel cross-talk within the IKK family controls innate immunity

(2011) Kristopher Clark et al.   BIOCHEMICAL JOURNAL

Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

(2011) X. Zhang et al.   DIABETES

Association Between Disease-Modifying Antirheumatic Drugs and Diabetes Risk in Patients With Rheumatoid Arthritis and Psoriasis

(2011) Daniel H. Solomon   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

The TRAF-associated protein TANK facilitates cross-talk within the I B kinase family during Toll-like receptor signaling

(2011) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

(2010) Takahisa Nakamura et al.   CELL

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

Sphingolipids and insulin resistance: the five Ws

(2010) Scott A Summers   CURRENT OPINION IN LIPIDOLOGY

Functional Heterogeneity of CD11c-positive Adipose Tissue Macrophages in Diet-induced Obese Mice

(2010) Pingping Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Protein Kinase IKKɛ Regulates Energy Balance in Obese Mice

(2009) Shian-Huey Chiang et al.   CELL

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

Human Adipose Tissue Macrophages: M1 and M2 Cell Surface Markers in Subcutaneous and Omental Depots and after Weight Loss

(2009) Judith Aron-Wisnewsky et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

(2009) Jian Liu et al.   NATURE MEDICINE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

The NF-κB-independent functions of IKK subunits in immunity and cancer

(2009) Alain Chariot   TRENDS IN CELL BIOLOGY

The Emerging Genetic Architecture of Type 2 Diabetes

(2008) Alessandro Doria et al.   Cell Metabolism

Insulin sensitivity: modulation by nutrients and inflammation

(2008) Simon Schenk et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic NF- B essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis

(2008) F. T. Wunderlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES