Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells

Evidence That Niacin Inhibits Acute Vascular Inflammation and Improves Endothelial Dysfunction Independent of Changes in Plasma Lipids

(2010) Ben J. Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nicotinic acid– and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice

(2010) Julien Hanson et al.   JOURNAL OF CLINICAL INVESTIGATION

CXC Chemokine Ligand 4 Induces a Unique Transcriptome in Monocyte-Derived Macrophages

(2010) C. A. Gleissner et al.   JOURNAL OF IMMUNOLOGY

The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6–HDL and LDL Treatment Strategies in Atherosclerosis)

(2010) Todd C. Villines et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Niacin stimulates adiponectin secretion through the GPR109A receptor

(2009) Eric P. Plaisance et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Macrophage Diversity and Polarization in Atherosclerosis

(2009) Alberto Mantovani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

(2009) Laurent Yvan-Charvet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin

(2009) Janet E. Digby et al.   ATHEROSCLEROSIS

Effects of Niacin on Cell Adhesion and Early Atherogenesis: Biochemical and Functional Findings in Endothelial Cells

(2009) Subramaniam Tavintharan et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Nicotinic acid: A new look at an old drug

(2009) John A. Farmer   Current Atherosclerosis Reports

Nicotinic acid and the prevention of coronary artery disease

(2009) Janet E Digby et al.   CURRENT OPINION IN LIPIDOLOGY

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

(2009) Robert W. Walters et al.   JOURNAL OF CLINICAL INVESTIGATION

LXR and ABCA1 control cholesterol homeostasis in the proximal mouse epididymis in a cell-specific manner

(2009) Aurélia Ouvrier et al.   JOURNAL OF LIPID RESEARCH

Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function

(2009) Justin M.S. Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Update on strategies to increase HDL quantity and function

(2009) Danielle Duffy et al.   Nature Reviews Cardiology

Mechanism of Action of Niacin

(2008) Vaijinath S. Kamanna et al.   AMERICAN JOURNAL OF CARDIOLOGY

CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways

(2008) Fabrizio Montecucco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Is high HDL cholesterol always good?

(2008) Anders G. Olsson   ANNALS OF MEDICINE

Extended-Release Niacin Alters the Metabolism of Plasma Apolipoprotein (Apo) A-I and ApoB-Containing Lipoproteins

(2008) Stefania Lamon-Fava et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Niacin Increases HDL by Reducing Hepatic Expression and Plasma Levels of Cholesteryl Ester Transfer Protein in APOE*3Leiden.CETP Mice

(2008) José W.A. van der Hoorn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Rimonabant, a Selective Cannabinoid CB1 Receptor Antagonist, Inhibits Atherosclerosis in LDL Receptor–Deficient Mice

(2008) Frédérique Dol-Gleizes et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells

(2008) Shobha H. Ganji et al.   ATHEROSCLEROSIS

The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist

(2008) Hua Tang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis

(2008) Ralph Gareus et al.   Cell Metabolism

RhoA/ROCK I signalling downstream of the P2Y13 ADP-receptor controls HDL endocytosis in human hepatocytes

(2008) C MALAVAL et al.   CELLULAR SIGNALLING

Niacin: An old drug rejuvenated

(2008) Vaijinath S. Kamanna et al.   Current Atherosclerosis Reports

3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice

(2008) Graeme Semple et al.   JOURNAL OF MEDICINAL CHEMISTRY

Is raising HDL a futile strategy for atheroprotection?

(2008) Tisha Joy et al.   NATURE REVIEWS DRUG DISCOVERY

Spotlight on HDL-raising therapies: insights from the torcetrapib trials

(2008) Anatol Kontush et al.   Nature clinical practice. Cardiovascular medicine

Management of Lipids in the Prevention of Cardiovascular Events

(2007) Helene Glassberg et al.   Annual Review of Medicine

Nicotinic Acid: Pharmacological Effects and Mechanisms of Action

(2007) Andreas Gille et al.   Annual Review of Pharmacology and Toxicology