标题
Pharmacogenetics of drug transporters in the enterohepatic circulation
作者
关键词
-
出版物
PHARMACOGENOMICS
Volume 12, Issue 5, Pages 611-631
出版商
Future Medicine Ltd
发表日期
2011-05-27
DOI
10.2217/pgs.11.53
参考文献
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- (2011) Lin Jia et al. Annual Review of Physiology
- Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients withPseudoxanthoma elasticumprevent the liver from providing sufficient vitamin K to the periphery?
- (2011) Piet Borst et al. CELL CYCLE
- Genetic Polymorphisms of ATP-Binding Cassette Transporters ABCB1 and ABCC2 and their Impact on Drug Disposition
- (2011) Vincent Haufroid CURRENT DRUG TARGETS
- ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions
- (2011) Beatrice Marquez et al. CURRENT DRUG TARGETS
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- (2011) Ute I. Schwarz et al. Pharmacogenetics and Genomics
- Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake
- (2011) M. Niemi et al. PHARMACOLOGICAL REVIEWS
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- (2010) Matthew H. Crouthamel et al. AAPS Journal
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- (2010) Riitta Sallinen et al. ANNALS OF MEDICINE
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- (2010) Jennifer Bordeaux et al. BIOTECHNIQUES
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- (2010) Stephan Kemp et al. BRAIN PATHOLOGY
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- (2010) Pei-Hua Lu et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2010) E. K. Pollex et al. DRUG METABOLISM AND DISPOSITION
- ABCC2/Abcc2: a multispecific transporter with dominant excretory functions
- (2010) Katalin Jemnitz et al. DRUG METABOLISM REVIEWS
- Hepatic OATP and OCT uptake transporters: their role for drug-drug interactions and pharmacogenetic aspects
- (2010) Christina Fahrmayr et al. DRUG METABOLISM REVIEWS
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- (2010) Hiroyuki Kusuhara et al. DRUG METABOLISM REVIEWS
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- (2010) Laila Nurmohamed et al. EPILEPSIA
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- (2010) Maren Poguntke et al. Expert Opinion on Drug Metabolism & Toxicology
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- (2010) Alice C Rodrigues Expert Opinion on Drug Metabolism & Toxicology
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- (2010) Stefan Russmann et al. HEPATOLOGY
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- (2010) Hiromistu Ban et al. JOURNAL OF GASTROENTEROLOGY
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- (2010) Lily Jakulj et al. JOURNAL OF LIPID RESEARCH
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- (2010) Takeshi Sakata et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Membrane transporters in drug development
- (2010) NATURE REVIEWS DRUG DISCOVERY
- The effects of the SLCO2B1 c.1457C>T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans
- (2010) Junko Imanaga et al. Pharmacogenetics and Genomics
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- (2010) Sook Wah Yee et al. PHARMACOGENOMICS
- Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation
- (2010) C. D. Klaassen et al. PHARMACOLOGICAL REVIEWS
- Emerging New Technologies in Pharamcogenomics: Rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1)
- (2010) Toshihisa Ishikawa et al. PHARMACOLOGY & THERAPEUTICS
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- (2010) Coen Paulusma et al. SEMINARS IN LIVER DISEASE
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- (2010) Anne Davit-Spraul et al. SEMINARS IN LIVER DISEASE
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- (2010) Ryan E. Morgan et al. TOXICOLOGICAL SCIENCES
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- (2009) King Leung Fung et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
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- (2009) M. Ansari et al. BLOOD
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- (2009) A Kalliokoski et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2009) Kimie Sai et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
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- (2009) N Picard et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2009) M V Tzvetkov et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2009) D L Kroetz et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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- (2009) Matthias Brandsch Expert Opinion on Drug Metabolism & Toxicology
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- (2009) Ichiro Ieiri et al. Expert Opinion on Drug Metabolism & Toxicology
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- (2009) Anne T. Nies et al. HEPATOLOGY
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- (2009) Jennifer J Kiser et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
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- (2009) Moto Kajiwara et al. JOURNAL OF HUMAN GENETICS
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- (2009) Siew-Kee Low et al. JOURNAL OF HUMAN GENETICS
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- (2009) Pei-Chieng Cha et al. JOURNAL OF HUMAN GENETICS
- Pharmacogenetics of Membrane Transporters: An Update on Current Approaches
- (2009) Tristan M. Sissung et al. MOLECULAR BIOTECHNOLOGY
- Interplay of Drug Metabolism and Transport: A Real Phenomenon or an Artifact of the Site of Measurement?
- (2009) Christopher J. Endres et al. MOLECULAR PHARMACEUTICS
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- (2009) Leslie Z. Benet MOLECULAR PHARMACEUTICS
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- (2009) K. Sandy Pang et al. MOLECULAR PHARMACEUTICS
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- (2009) Ann K Daly et al. NATURE GENETICS
- Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response
- (2009) Edward B. Mougey et al. Pharmacogenetics and Genomics
- Impact of regulatory polymorphisms in organic anion transporter genes in the human liver
- (2009) Masayo Aoki et al. Pharmacogenetics and Genomics
- Meta-analysis in genome-wide association studies
- (2009) Eleftheria Zeggini et al. PHARMACOGENOMICS
- Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function
- (2009) Ying Chen et al. PHARMACOGENOMICS JOURNAL
- The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy
- (2009) S P R Romaine et al. PHARMACOGENOMICS JOURNAL
- Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
- (2009) O. M. Woodward et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
- (2009) S. G. Aller et al. SCIENCE
- Meta-Analysis of the Effect of MDR1 C3435T Polymorphism on Cyclosporine Pharmacokinetics
- (2008) Zhi-Ping Jiang et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Association of ATP-Binding Cassette, Sub-family C, Number 2 (ABCC2) Genotype with Pharmacokinetics of Irinotecan in Japanese Patients with Metastatic Colorectal Cancer Treated with Irinotecan Plus Infusional 5-Fluorouracil/Leucovorin (FOLFIRI)
- (2008) Ken-ichi Fujita et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- The biological and clinical role of drug transporters at the intestinal barrier
- (2008) Roos L. Oostendorp et al. CANCER TREATMENT REVIEWS
- Impact of Genetic Polymorphisms of Transporters on the Pharmacokinetic, Pharmacodynamic and Toxicological Properties of Anionic Drugs
- (2008) Kazuya Maeda et al. Drug Metabolism and Pharmacokinetics
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- (2008) Ulrike Gradhand et al. DRUG METABOLISM REVIEWS
- Could polymorphisms in ATP-binding cassette C3/multidrug resistance associated protein 3 (ABCC3/MRP3) modify colorectal cancer risk?
- (2008) Daniele Campa et al. EUROPEAN JOURNAL OF CANCER
- Implications of ABC transporters on the disposition of typical veterinary medicinal products
- (2008) Jan A. Schrickx et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs
- (2008) Anne T Nies et al. Expert Opinion on Drug Metabolism & Toxicology
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- (2008) Teruo Murakami et al. Expert Opinion on Drug Metabolism & Toxicology
- 6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4
- (2008) Daniel Janke et al. HUMAN MUTATION
- Polymorphisms inABCG2,ABCC3andCNT1genes and their possible impact on chemotherapy outcome of lung cancer patients
- (2008) Phillip J. Müller et al. INTERNATIONAL JOURNAL OF CANCER
- The Human Multidrug Resistance Protein 4 (MRP4, ABCC4): Functional Analysis of a Highly Polymorphic Gene
- (2008) N. Abla et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans
- (2008) T. Watanabe et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Novel Human Multidrug Resistance Gene MDR1 Variant G571A (G191R) Modulates Cancer Drug Resistance and Efflux Transport
- (2008) Z. Yang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
- (2008) Abbas Dehghan et al. LANCET
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- (2008) Otto Zach et al. LEUKEMIA & LYMPHOMA
- Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups
- (2008) Phillip Müller et al. LEUKEMIA RESEARCH
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- (2008) Orsolya Polgar et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
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- (2008) NEW ENGLAND JOURNAL OF MEDICINE
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- (2008) S.-F. Zhou XENOBIOTICA
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- (2008) B. Hagenbuch et al. XENOBIOTICA
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- (2008) Tsutomu Nakamura et al. Current Drug Delivery
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