ABCC2/Abcc2: a multispecific transporter with dominant excretory functions

Advancement of Structure-Activity Relationship of Multidrug Resistance-Associated Protein 2 Interactions

(2009) Li Xing et al.   AAPS Journal

Proliferation of Hepatocyte Progenitor Cells Isolated from Adult Human Livers in Serum-Free Medium

(2009) Kazunori Sasaki et al.   CELL TRANSPLANTATION

ABC Efflux Pump-Based Resistance to Chemotherapy Drugs

(2009) Paul D. W. Eckford et al.   CHEMICAL REVIEWS

Functionally Overlapping Roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the Elimination of Methotrexate and Its Main Toxic Metabolite 7-Hydroxymethotrexate In vivo

(2009) M. L.H. Vlaming et al.   CLINICAL CANCER RESEARCH

Multidrug Resistance Protein 2-Mediated Estradiol-17 -D-glucuronide Transport Potentiation: In Vitro-in Vivo Correlation and Species Specificity

(2009) K. Heredi-Szabo et al.   DRUG METABOLISM AND DISPOSITION

Complex Pharmacokinetic Behavior of Ezetimibe Depends on Abcc2, Abcc3, and Abcg2

(2009) D. R. de Waart et al.   DRUG METABOLISM AND DISPOSITION

Effect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and Inhibitors

(2009) E. Kis et al.   DRUG METABOLISM AND DISPOSITION

Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content

(2009) Coen C. Paulusma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Metabolism and Biliary Excretion of Valerenic Acid in Isolated Perfused Rat Livers: Role of Mrp2 (Abcc2)

(2009) Alexandra Maier-Salamon et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Integration of Preclinical and Clinical Data with Pharmacokinetic Modeling and Simulation to Evaluate Fexofenadine as a Probe for Hepatobiliary Transport Function

(2009) Brandon Swift et al.   PHARMACEUTICAL RESEARCH

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

(2009) Pär Matsson et al.   PHARMACEUTICAL RESEARCH

Hepatobiliary Disposition of Thyroid Hormone in Mrp2-Deficient TR− Rats: Reduced Biliary Excretion of Thyroxine Glucuronide Does Not Prevent Xenobiotic-Induced Hypothyroidism

(2009) Lloyd Lecureux et al.   TOXICOLOGICAL SCIENCES

Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene

(2008) Jia-jia Ma et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins

(2008) Stefan Leyers et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Telmisartan pharmacokinetics in Japanese renal transplant recipients

(2008) Masatomo Miura et al.   CLINICA CHIMICA ACTA

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the In vivo Elimination of Methotrexate and its Main Toxic Metabolite 7-hydroxymethotrexate

(2008) M. L.H. Vlaming et al.   CLINICAL CANCER RESEARCH

Identification of the Transporters Involved in the Hepatobiliary Transport and Intestinal Efflux of Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) Glucuronide, a Pharmacologically Active Metabolite of S-8921

(2008) S. Sakamoto et al.   DRUG METABOLISM AND DISPOSITION

Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)

(2008) S. R. Miranda et al.   DRUG METABOLISM AND DISPOSITION

Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of  -Lactam Antibiotics

(2008) Y. Kato et al.   DRUG METABOLISM AND DISPOSITION

Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport

(2008) N. Yoshida et al.   DRUG METABOLISM AND DISPOSITION

Transport of Diclofenac by Breast Cancer Resistance Protein (ABCG2) and Stimulation of Multidrug Resistance Protein 2 (ABCC2)-Mediated Drug Transport by Diclofenac and Benzbromarone

(2008) J. S. Lagas et al.   DRUG METABOLISM AND DISPOSITION

Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin

(2008) S. Kitamura et al.   DRUG METABOLISM AND DISPOSITION

Molecular cloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2)

(2008) Masa Yasunaga et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Support vector machine and pharmacophore-based prediction models of multidrug-resistance protein 2 (MRP2) inhibitors

(2008) Hui Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Utilization of membrane vesicle preparations to study drug–ABC transporter interactions

(2008) Hristos Glavinas et al.   Expert Opinion on Drug Metabolism & Toxicology

Expression and localization of ATP binding cassette (ABC) family of drug transporters in gastric hepatoid adenocarcinomas

(2008) S Kamata et al.   HISTOPATHOLOGY

Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): Evasion of MRP-2 mediated efflux

(2008) Ritesh Jain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Prediction and Identification of Drug Interactions with the Human ATP-Binding Cassette Transporter Multidrug-Resistance Associated Protein 2 (MRP2; ABCC2)

(2008) Jenny M. Pedersen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Decreased Mrp2-Dependent Bile Flow in the Post-Warm Ischemic Rat Liver

(2008) Daisuke Ban et al.   JOURNAL OF SURGICAL RESEARCH

Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin

(2008) Si Xie et al.   Journal of Translational Medicine

Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats

(2008) Fumie Abe et al.   LIFE SCIENCES

Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology

(2008) Nazzareno Ballatori et al.   MOLECULAR ASPECTS OF MEDICINE

Identification of Regions Required for Apical Membrane Localization of Human Multidrug Resistance Protein 2

(2008) P. E. Bandler et al.   MOLECULAR PHARMACOLOGY

Subcellular localization of transporters along the rat blood–brain barrier and blood–cerebral-spinal fluid barrier by in vivo biotinylation

(2008) L.M. Roberts et al.   NEUROSCIENCE

Involvement of P-glycoprotein, Multidrug Resistance Protein 2 and Breast Cancer Resistance Protein in the Transport of Belotecan and Topotecan in Caco-2 and MDCKII Cells

(2008) Hong Li et al.   PHARMACEUTICAL RESEARCH

MRP2 involvement in renal proximal tubular elimination of methylmercury mediated by DMPS or DMSA

(2008) Rudolfs K. Zalups et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis

(2007) S Teng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes

(2007) György Lengyel et al.   HEPATOLOGY RESEARCH

Disturbed colocalization of multidrug resistance protein 2 and radixin in human cholestatic liver diseases

(2007) Hideyuki Kojima et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Metabolism and Disposition of Resveratrol in the Isolated Perfused Rat Liver: Role of Mrp2 in the Biliary Excretion of Glucuronides

(2007) Alexandra Maier‐Salamon et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity

(2007) Jin Kyung Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY