Efflux and uptake transporters as determinants of statin response

Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1

(2010) Stefan Oswald et al.   Pharmacogenetics and Genomics

The expression of efflux and uptake transporters are regulated by statins in Caco-2 and HepG2 cells

(2009) Alice Cristina Rodrigues et al.   ACTA PHARMACOLOGICA SINICA

Identification of Genetic Variants Associated With Response to Statin Therapy

(2009) Jessica L. Mega et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

(2009) Laurent Yvan-Charvet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

No significant effect ofABCB1haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin

(2009) Jenni E. Keskitalo et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

(2009) Michael J. Knauer et al.   CIRCULATION RESEARCH

ABCG2 Polymorphism Markedly Affects the Pharmacokinetics of Atorvastatin and Rosuvastatin

(2009) J E Keskitalo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Rhabdomyolysis associated with fibrate therapy: review of 76 published cases and a new case report

(2009) Jianyong Wu et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells

(2009) Daisuke Yamasaki et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The SLCO1B1*5Genetic Variant Is Associated With Statin-Induced Side Effects

(2009) Deepak Voora et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myopathy with statin–fibrate combination therapy: clinical considerations

(2009) Terry A. Jacobson   Nature Reviews Endocrinology

ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment

(2008) Ivanise Marina Moretti Rebecchi et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacokinetic Comparison of the Potential Over-the-Counter Statins Simvastatin, Lovastatin, Fluvastatin and Pravastatin

(2008) Pertti J Neuvonen et al.   CLINICAL PHARMACOKINETICS

ABCB1 Haplotypes Differentially Affect the Pharmacokinetics of the Acid and Lactone Forms of Simvastatin and Atorvastatin

(2008) JE Keskitalo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin

(2008) S. Kitamura et al.   DRUG METABOLISM AND DISPOSITION

Atorvastatin Inhibits ABCA1 Expression and Cholesterol Efflux in THP-1 Macrophages by an LXR-dependent Pathway

(2008) Guosong Qiu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins

(2008) A. R. Tall   JOURNAL OF INTERNAL MEDICINE

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

(2008) Paul D. Dobson et al.   NATURE REVIEWS DRUG DISCOVERY

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy

(2008) Philippe Couvert et al.   PHARMACOGENOMICS

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

(2008) Chao-Yung Wang et al.   TRENDS IN MOLECULAR MEDICINE

The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation

(2007) Jenny Wong et al.   ATHEROSCLEROSIS

Coexistence of Foam Cells and Hypocholesterolemia in Mice Lacking the ABC Transporters A1 and G1

(2007) Ruud Out et al.   CIRCULATION RESEARCH