标题
Therapeutic modulators of STAT signalling for human diseases
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 12, Issue 8, Pages 611-629
出版商
Springer Nature
发表日期
2013-08-01
DOI
10.1038/nrd4088
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- A Chemical Biology Approach to Developing STAT Inhibitors: Molecular Strategies for Accelerating Clinical Translation
- (2015) Erik A. Nelson et al. Oncotarget
- Identification and characterization of small molecule inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening
- (2013) Mingming Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells
- (2013) Mi-Jung Kim et al. CANCER LETTERS
- A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation
- (2013) X. Zhang et al. CANCER RESEARCH
- Molecular Pathways: JAK/STAT Pathway: Mutations, Inhibitors, and Resistance
- (2013) A. Quintas-Cardama et al. CLINICAL CANCER RESEARCH
- Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of NSCLC
- (2013) A.G. Pallis et al. LUNG CANCER
- JAKs and STATs in Immunity, Immunodeficiency, and Cancer
- (2013) John J. O'Shea et al. NEW ENGLAND JOURNAL OF MEDICINE
- Brevilin A, a Novel Natural Product, Inhibits Janus Kinase Activity and Blocks STAT3 Signaling in Cancer Cells
- (2013) Xing Chen et al. PLoS One
- Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells
- (2012) Hee Jung Um et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody
- (2012) Kuen-Feng Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- HO-3867, a STAT3 inhibitor induces apoptosis by inactivation of STAT3 activity in BRCA1-mutated ovarian cancer cells
- (2012) Brent J. Tierney et al. CANCER BIOLOGY & THERAPY
- Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis
- (2012) Fan Yang et al. CANCER BIOLOGY & THERAPY
- Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells
- (2012) Jie Yang et al. CANCER LETTERS
- Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo
- (2012) P. Rajendran et al. Cancer Prevention Research
- The Synthetic Triterpenoid CDDO-Methyl Ester Delays Estrogen Receptor-Negative Mammary Carcinogenesis in Polyoma Middle T Mice
- (2012) K. Tran et al. Cancer Prevention Research
- Inhibition of phosphorylated STAT3 by cucurbitacin I enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells
- (2012) Charn-Jung Chang et al. CHILDS NERVOUS SYSTEM
- Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer
- (2012) M. Sen et al. CLINICAL CANCER RESEARCH
- Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity
- (2012) Kuen-Feng Chen et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The JAK-STAT Pathway at Twenty
- (2012) George R. Stark et al. IMMUNITY
- Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-κB Pathway
- (2012) Chien-Liang Lin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway
- (2012) Ke Sai et al. JOURNAL OF NEURO-ONCOLOGY
- A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line
- (2012) Inès Souissi et al. Molecular Cancer
- Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells
- (2012) Sangkil Nam et al. Molecular Oncology
- Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling
- (2012) Sangkil Nam et al. Molecular Oncology
- Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells
- (2012) Sangkil Nam et al. Molecular Oncology
- SomaticSTAT3Mutations in Large Granular Lymphocytic Leukemia
- (2012) Hanna L.M. Koskela et al. NEW ENGLAND JOURNAL OF MEDICINE
- STAT3 Is Activated by JAK2 Independent of Key Oncogenic Driver Mutations in Non-Small Cell Lung Carcinoma
- (2012) Brendan D. Looyenga et al. PLoS One
- Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway
- (2012) Cheng-Liang Yang et al. PLoS One
- Anti-Angiogenic Activity of a Small Molecule STAT3 Inhibitor LLL12
- (2012) Hemant K. Bid et al. PLoS One
- Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines
- (2012) Matthew A. Bill et al. PLoS One
- Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor-Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model
- (2012) Bhuvanesh Dave et al. PLoS One
- Calpain/SHP-1 Interaction by Honokiol Dampening Peritoneal Dissemination of Gastric Cancer in nu/nu Mice
- (2012) Shing Hwa Liu et al. PLoS One
- Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
- (2012) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a novelSTAT3mutation in a patient with hyper-IgE syndrome
- (2012) Trine H. Mogensen et al. SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
- First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy
- (2012) Malabika Sen et al. Cancer Discovery
- Chemosensitization of tumors by resveratrol
- (2011) Subash C. Gupta et al. Annals of the New York Academy of Sciences
- STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells
- (2011) Li Zhou et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
- (2011) E. A. Nelson et al. BLOOD
- The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines
- (2011) Stacey L Fossey et al. BMC CANCER
- Inhibitory effects of the JAK inhibitor CP690,550 on human CD4+ T lymphocyte cytokine production
- (2011) Kiyoshi Migita et al. BMC IMMUNOLOGY
- Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
- (2011) Radhamani Kannaiyan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells
- (2011) Han-Shui Hsu et al. CANCER
- HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition
- (2011) Karuppaiyah Selvendiran et al. CANCER BIOLOGY & THERAPY
- Curcumin Induces the Differentiation of Myeloid-Derived Suppressor Cells and Inhibits Their Interaction with Cancer Cells and Related Tumor Growth
- (2011) S. P. Tu et al. Cancer Prevention Research
- Bone Marrow Stroma-Secreted Cytokines Protect JAK2V617F-Mutated Cells from the Effects of a JAK2 Inhibitor
- (2011) T. Manshouri et al. CANCER RESEARCH
- Antiangiogenic and Antimetastatic Activity of JAK Inhibitor AZD1480
- (2011) H. Xin et al. CANCER RESEARCH
- Resveratrol Potentiates the Cytotoxic Oxidative Stress Induced by Chemotherapy in Human Colon Cancer Cells
- (2011) Francisca M. Santandreu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Phase II study of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer
- (2011) Cristina Grávalos et al. Clinical & Translational Oncology
- Effective treatment of experimental ragweed-induced asthma with STAT-6-IP, a topically delivered cell-penetrating peptide
- (2011) Y. Wang et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation
- (2011) Beom-Joon Lee et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell
- (2011) Xiaoli Zhang et al. INTERNATIONAL JOURNAL OF CANCER
- Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice
- (2011) Grace-Ifeyinwa Onimoe et al. INVESTIGATIONAL NEW DRUGS
- Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis
- (2011) Yi-Ping Yang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
- (2011) Peramaiyan Rajendran et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis
- (2011) Luyan Liu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance
- (2011) Hilmar Quentmeier et al. Journal of Hematology & Oncology
- Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma
- (2011) Wei-Tien Tai et al. JOURNAL OF HEPATOLOGY
- STAT6 Expression in Multiple Cell Types Mediates the Cooperative Development of Allergic Airway Disease
- (2011) S. P. Chapoval et al. JOURNAL OF IMMUNOLOGY
- Potent and Selective Phosphopeptide Mimetic Prodrugs Targeted to the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3
- (2011) Pijus K. Mandal et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
- (2011) Muthu K. Shanmugam et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression
- (2011) Gamal Badr et al. Lipids in Health and Disease
- JAK1 Activates STAT3 Activity in Non-Small-Cell Lung Cancer Cells and IL-6 Neutralizing Antibodies Can Suppress JAK1-STAT3 Signaling
- (2011) L. Song et al. MOLECULAR CANCER THERAPEUTICS
- Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma
- (2011) B. C. McFarland et al. MOLECULAR CANCER THERAPEUTICS
- Biological activity of piceatannol: Leaving the shadow of resveratrol
- (2011) Hanna Piotrowska et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- STAT1Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis
- (2011) Frank L. van de Veerdonk et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion
- (2011) Meng Sun et al. PROSTATE
- The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma
- (2011) E Derenzini et al. Blood Cancer Journal
- A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes
- (2010) Xiaolei Zhang et al. BIOCHEMICAL PHARMACOLOGY
- Th1 versus Th17: Are T cell cytokines relevant in multiple sclerosis?
- (2010) Amy E. Lovett-Racke et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia
- (2010) F. Ravandi et al. BLOOD
- Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms
- (2010) A. Quintas-Cardama et al. BLOOD
- Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway
- (2010) Keinosuke Ryu et al. BMC CANCER
- Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway
- (2010) Feng Li et al. BRITISH JOURNAL OF PHARMACOLOGY
- γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent
- (2010) Peramaiyan Rajendran et al. BRITISH JOURNAL OF PHARMACOLOGY
- Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
- (2010) Feng Li et al. CANCER LETTERS
- Inhibition of EGFR-STAT3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma
- (2010) R. J. Leeman-Neill et al. Cancer Prevention Research
- STAT2 Contributes to Promotion of Colorectal and Skin Carcinogenesis
- (2010) A. M. Gamero et al. Cancer Prevention Research
- Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells
- (2010) L. Lin et al. CANCER RESEARCH
- Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells
- (2010) J. Lee et al. CARCINOGENESIS
- Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway
- (2010) Y. Dong et al. CARCINOGENESIS
- Inhibition of p-STAT3 Enhances IFN- Efficacy against Metastatic Melanoma in a Murine Model
- (2010) L. Y. Kong et al. CLINICAL CANCER RESEARCH
- Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors
- (2010) R. J. Leeman-Neill et al. CLINICAL CANCER RESEARCH
- Targeted Blockage of Signal Transducer and Activator of Transcription 5 Signaling Pathway with Decoy Oligodeoxynucleotides Suppresses Leukemic K562 Cell Growth
- (2010) Xiaozhong Wang et al. DNA AND CELL BIOLOGY
- Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin
- (2010) Tingyan Liu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor
- (2010) Alfonso Quintás-Cardama et al. INVESTIGATIONAL NEW DRUGS
- A Cell-permeable Stat3 SH2 Domain Mimetic Inhibits Stat3 Activation and Induces Antitumor Cell Effectsin Vitro
- (2010) Wei Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- γ-Tocotrienol but Not γ-Tocopherol Blocks STAT3 Cell Signaling Pathway through Induction of Protein-tyrosine Phosphatase SHP-1 and Sensitizes Tumor Cells to Chemotherapeutic Agents
- (2010) Ramaswamy Kannappan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-4 Regulates Skin Homeostasis and the Predisposition toward Allergic Skin Inflammation
- (2010) S. Sehra et al. JOURNAL OF IMMUNOLOGY
- Targeting transcription factor Stat4 uncovers a role for interleukin-18 in the pathogenesis of severe lupus nephritis in mice
- (2010) Julia Menke et al. KIDNEY INTERNATIONAL
- The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity
- (2010) Aya Nakaya et al. LEUKEMIA RESEARCH
- A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
- (2010) Li Lin et al. Molecular Cancer
- Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3
- (2010) Fan Yang et al. MOLECULAR CANCER THERAPEUTICS
- Microtubule-Targeted Chemotherapeutic Agents Inhibit Signal Transducer and Activator of Transcription 3 (STAT3) Signaling
- (2010) S. R. Walker et al. MOLECULAR PHARMACOLOGY
- Dasatinib versus Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia
- (2010) Hagop Kantarjian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors
- (2010) Jianyong Chen et al. ACS Medicinal Chemistry Letters
- Identification of a New Series of STAT3 Inhibitors by Virtual Screening
- (2010) Kenji Matsuno et al. ACS Medicinal Chemistry Letters
- A Novel STAT6 Inhibitor AS1517499 Ameliorates Antigen-Induced Bronchial Hypercontractility in Mice
- (2009) Yoshihiko Chiba et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress
- (2009) Hyun Kyoung Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors
- (2009) Shinya Nagashima et al. BIOORGANIC & MEDICINAL CHEMISTRY
- LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
- (2009) B Fuh et al. BRITISH JOURNAL OF CANCER
- The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors
- (2009) Michael Hedvat et al. CANCER CELL
- LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression
- (2009) Ja Eun Kim et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Evaluation of anti-leukemia effect of resveratrol by modulating SATA3 signaling
- (2009) Tan Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Inhibitory effect of cucurbitacin E on pancreatic cancer cells growth via STAT3 signaling
- (2009) Chunyan Sun et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Targeting Signal Transducer and Activator of Transcription Signaling Pathway in Leukemias
- (2009) Mustafa Benekli et al. JOURNAL OF CLINICAL ONCOLOGY
- Boswellic Acid Blocks Signal Transducers and Activators of Transcription 3 Signaling, Proliferation, and Survival of Multiple Myeloma via the Protein Tyrosine Phosphatase SHP-1
- (2009) Ajaikumar B. Kunnumakkara et al. MOLECULAR CANCER RESEARCH
- Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation
- (2009) Xuejun Xu et al. PLoS One
- Interleukin-13 Augments Bronchial Smooth Muscle Contractility with an Up-Regulation of RhoA Protein
- (2008) Yoshihiko Chiba et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells
- (2008) Esha Madan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors
- (2008) Shinya Nagashima et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening
- (2008) Wenshan Hao et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3
- (2008) E. A. Nelson et al. BLOOD
- CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells
- (2008) Zhenfeng Duan et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Lack of toxicity of a STAT3 decoy oligonucleotide
- (2008) Malabika Sen et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
- (2008) D.-S. Shin et al. CANCER RESEARCH
- AP-1 and STAT-1 decoy oligodeoxynucleotides attenuate transplant vasculopathy in rat cardiac allografts
- (2008) T. H.W. Stadlbauer et al. CARDIOVASCULAR RESEARCH
- Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5
- (2008) Judith Müller et al. CHEMBIOCHEM
- PRAVASTATIN ATTENUATES INTERFERON-γ ACTION VIA MODULATION OF STAT1 TO PREVENT AORTIC ATHEROSCLEROSIS IN APOLIPOPROTEIN E-KNOCKOUT MICE
- (2008) Xiao-Xu Zhou et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Interleukin-4, Interleukin-13, Signal Transducer and Activator of Transcription Factor 6, and Allergic Asthma
- (2008) Douglas Kuperman et al. CURRENT MOLECULAR MEDICINE
- Targeting STAT3 in cancer: how successful are we?
- (2008) Peibin Yue et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Avicin D Selectively Induces Apoptosis and Downregulates p-STAT-3, bcl-2, and Survivin in Cutaneous T-Cell Lymphoma Cells
- (2008) Chunlei Zhang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
- (2008) Ann-Lii Cheng et al. LANCET ONCOLOGY
- Resveratrol addiction: To die or not to die
- (2008) Mehdi Shakibaei et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
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