Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

Inhibition of JAK1, 2/STAT3 Signaling Induces Apoptosis, Cell Cycle Arrest, and Reduces Tumor Cell Invasion in Colorectal Cancer Cells

(2015) Hua Xiong et al.   NEOPLASIA

Inhibition of p-STAT3 Enhances IFN-  Efficacy against Metastatic Melanoma in a Murine Model

(2010) L. Y. Kong et al.   CLINICAL CANCER RESEARCH

Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression

(2010) J. Wei et al.   CLINICAL CANCER RESEARCH

Stat3 activation is required for the growth of U87 cell-derived tumours in mice

(2009) Atreyi Dasgupta et al.   EUROPEAN JOURNAL OF CANCER

Quantitative Phosphoproteomic Analysis of the STAT3/IL-6/HIF1α Signaling Network: An Initial Study in GSC11 Glioblastoma Stem Cells

(2009) Carol L. Nilsson et al.   JOURNAL OF PROTEOME RESEARCH

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters

(2009) V Martin et al.   ONCOGENE

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells

(2008) Jeongwu Lee et al.   CANCER CELL

A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells

(2008) Ling-Yuan Kong et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tamoxifen Stimulates the Growth of Cyclin D1-Overexpressing Breast Cancer Cells by Promoting the Activation of Signal Transducer and Activator of Transcription 3

(2008) Y. Ishii et al.   CANCER RESEARCH

Guggulsterone, a Farnesoid X Receptor Antagonist, Inhibits Constitutive and Inducible STAT3 Activation through Induction of a Protein Tyrosine Phosphatase SHP-1

(2008) K. S. Ahn et al.   CANCER RESEARCH

Molecular Basis for the Critical Role of Suppressor of Cytokine Signaling-1 in Melanoma Brain Metastasis

(2008) F.-J. Huang et al.   CANCER RESEARCH

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators

(2008) H.-W. Lo et al.   CLINICAL CANCER RESEARCH

The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas

(2008) M. Abou-Ghazal et al.   CLINICAL CANCER RESEARCH

Brain Tumor Stem Cells

(2008) Erik Sulman et al.   CURRENT PROBLEMS IN CANCER

Anti-Apoptosis Mechanisms in Malignant Gliomas

(2008) David S. Ziegler et al.   JOURNAL OF CLINICAL ONCOLOGY

Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis

(2008) Christine E. Eyler et al.   JOURNAL OF CLINICAL ONCOLOGY

Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas

(2008) E. C. Brantley et al.   MOLECULAR CANCER RESEARCH

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Apoptotic signaling by c-MYC

(2008) B Hoffman et al.   ONCOGENE

Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3

(2007) Rebecka Hellsten et al.   PROSTATE