The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

The Aberrant Expressions of Nuclear Matrix Proteins During the Apoptosis of Human Osteosarcoma Cells

(2010) Zhen-Li Zhao et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells

(2010) Lauren Friedman et al.   ANTI-CANCER DRUGS

Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro

(2010) Jayaraj Ravindran et al.   BIOCHEMICAL PHARMACOLOGY

Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway

(2010) Keinosuke Ryu et al.   BMC CANCER

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Curcumin Inhibits Constitutive STAT3 Phosphorylation in Human Pancreatic Cancer Cell lines and Downregulation of Survivin/BIRC5 Gene Expression

(2010) W. Glienke et al.   CANCER INVESTIGATION

Differential Inhibition of Protein Translation Machinery by Curcumin in Normal, Immortalized, and Malignant Oral Epithelial Cells

(2010) N. Chakravarti et al.   Cancer Prevention Research

Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells

(2010) L. Lin et al.   CANCER RESEARCH

IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-Induced STAT3 phosphorylation in human hepatocellular cancer cells

(2010) Yan Liu et al.   CELL CYCLE

Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy

(2010) Florian Heitz et al.   Expert Review of Anticancer Therapy

Safety and Pharmacokinetics of a Solid Lipid Curcumin Particle Formulation in Osteosarcoma Patients and Healthy Volunteers

(2010) Vikram S. Gota et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease

(2010) Vivek Ramshankar Yadav et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

(2010) Li Lin et al.   Molecular Cancer

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

(2010) Matthew A Bill et al.   Molecular Cancer

Priming of Signal Transducer and Activator of Transcription Proteins for Cytokine-Triggered Polyubiquitylation and Degradation by the A2A Adenosine Receptor

(2010) M. M. A. Safhi et al.   MOLECULAR PHARMACOLOGY

Overexpression of EGFR pathway-related genes in the circulation is highly correlated with EGFR mutations and overexpression in paired cancer tissue from patients with non-small cell lung cancer

(2010) Lin   ONCOLOGY REPORTS

Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents

(2009) Guang Liang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–activity relationship studies of curcumin analogues

(2009) James R. Fuchs et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

(2009) Ling Cen et al.   BMC CANCER

Characterization of STAT3 activation and expression in canine and human osteosarcoma

(2009) Stacey L Fossey et al.   BMC CANCER

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression

(2009) Melissa Paoloni et al.   BMC GENOMICS

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

(2009) Song-Shei Lin et al.   CANCER LETTERS

Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: Their inhibition by curcumin

(2009) Ji Hye Seo et al.   CANCER LETTERS

New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

(2009) Li Lin et al.   CANCER SCIENCE

Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells

(2009) Pay-Chin Leow et al.   INVESTIGATIONAL NEW DRUGS

Primary Osteogenic Sarcoma with Pulmonary Metastasis: Clinical Results and Prognostic Factors in 91 Patients

(2009) P. K. Wu et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Synergistic Role of Curcumin With Current Therapeutics in Colorectal Cancer: Minireview

(2009) Bhaumik B. Patel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo

(2008) V. Milacic et al.   CANCER RESEARCH

New mechanisms and therapeutic potential of curcumin for colorectal cancer

(2008) Isabel Villegas et al.   MOLECULAR NUTRITION & FOOD RESEARCH