Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells

(2011) Radhamani Kannaiyan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-γ and COX-2-dependent signals

(2010) Shing Hwa Liu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells

(2010) Feng Li et al.   CANCER LETTERS

Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation

(2010) M. Vaid et al.   CARCINOGENESIS

Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF- B and STAT3 pathways in head and neck cancer cells

(2010) M. A. Macha et al.   CARCINOGENESIS

NF-κB and STAT3 – key players in liver inflammation and cancer

(2010) Guobin He et al.   CELL RESEARCH

Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors

(2010) R. J. Leeman-Neill et al.   CLINICAL CANCER RESEARCH

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

(2010) Peramaiyan Rajendran et al.   CLINICAL CANCER RESEARCH

Systematic review of hepatocellular adenoma in China and other regions

(2010) Haoming Lin et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2)

(2010) Junfang Deng et al.   LIVER INTERNATIONAL

Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway byNanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

(2010) Diana Cirstea et al.   MOLECULAR CANCER THERAPEUTICS

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

(2010) Fan Yang et al.   MOLECULAR CANCER THERAPEUTICS

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line

(2009) Karnati R. Roy et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Novel treatments for hepatocellular cancer

(2009) S.H. Kerr et al.   CANCER LETTERS

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Combination chemotherapy of doxorubicin and paclitaxel for hepatocellular carcinoma in vitro and in vivo

(2009) Cheng Jin et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Honokiol-mediated Inhibition of PI3K/mTOR Pathway

(2009) Courtney Crane et al.   JOURNAL OF IMMUNOTHERAPY

Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN

(2008) Xiaoxia Sun et al.   CANCER LETTERS

Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction

(2008) E.-R. Hahm et al.   CLINICAL CANCER RESEARCH

Honokiol Suppresses Survival Signals Mediated by Ras-Dependent Phospholipase D Activity in Human Cancer Cells

(2008) A. Garcia et al.   CLINICAL CANCER RESEARCH

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo

(2008) Esther Raskopf et al.   JOURNAL OF HEPATOLOGY

Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?

(2008) David J. Newman   JOURNAL OF MEDICINAL CHEMISTRY

The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis

(2008) S. M. Raja et al.   MOLECULAR CANCER THERAPEUTICS

Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models

(2008) Wenli Hou et al.   PHYTOTHERAPY RESEARCH

Interleukin-6 Mediates G0/G1 Growth Arrest in Hepatocellular Carcinoma Through a STAT 3-Dependent Pathway

(2007) Dairmuid M. Moran et al.   JOURNAL OF SURGICAL RESEARCH