标题
HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond
作者
关键词
-
出版物
Nature Reviews Nephrology
Volume 12, Issue 3, Pages 157-168
出版商
Springer Nature
发表日期
2015-12-14
DOI
10.1038/nrneph.2015.193
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly
- (2015) Elena Gammella et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- New insights into iron regulation and erythropoiesis
- (2015) Airie Kim et al. CURRENT OPINION IN HEMATOLOGY
- MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury
- (2015) K. Bhatt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes
- (2015) Yutaka Tojo et al. MOLECULAR AND CELLULAR BIOLOGY
- Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients
- (2015) Anatole Besarab et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult
- (2015) Melanie Vogler et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Smooth muscle cell-specific Hif-1α deficiency suppresses angiotensin II-induced vascular remodelling in mice
- (2014) Masaki Imanishi et al. CARDIOVASCULAR RESEARCH
- HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore
- (2014) Sang-Ging Ong et al. CARDIOVASCULAR RESEARCH
- The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities
- (2014) K. McCafferty et al. Disease Models & Mechanisms
- Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis
- (2014) Yatrik M. Shah et al. GASTROENTEROLOGY
- Hypoxic Signaling During Tissue Repair and Regenerative Medicine
- (2014) Tessa Nauta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Human UTY(KDM6C) Is a Male-specificNϵ-Methyl Lysyl Demethylase
- (2014) Louise J. Walport et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia
- (2014) Chunzhang Yang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice
- (2014) Ruoli L. Chen et al. JOURNAL OF NEUROCHEMISTRY
- Activation of Hypoxia-Inducible Factors Prevents Diabetic Nephropathy
- (2014) L. Nordquist et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
- (2014) Tianshu Feng et al. MOLECULAR CELL
- Incidence of erythropoietin antibody-mediated pure red cell aplasia: the Prospective Immunogenicity Surveillance Registry (PRIMS)
- (2014) Iain C. Macdougall et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Oral adsorbent AST-120 potentiates the effect of erythropoietin-stimulating agents on Stage 5 chronic kidney disease patients: a randomized crossover study
- (2014) I.-W. Wu et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Hypoxic preconditioning protection is eliminated in HIF-1α knockout mice subjected to neonatal hypoxia–ischemia
- (2014) R. Ann Sheldon et al. PEDIATRIC RESEARCH
- Mimicking Hypoxia to Treat Anemia: HIF-Stabilizer BAY 85-3934 (Molidustat) Stimulates Erythropoietin Production without Hypertensive Effects
- (2014) Ingo Flamme et al. PLoS One
- OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
- (2014) R. S. Singleton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Short-term treatment with a novel HIF-prolyl hydroxylase inhibitor (GSK1278863) failed to improve measures of performance in subjects with claudication-limited peripheral artery disease
- (2014) Eric Olson et al. VASCULAR MEDICINE
- The roles of Jumonji-type oxygenases in human disease
- (2014) Catrine Johansson et al. Epigenomics
- Selective Small Molecule Probes for the Hypoxia Inducible Factor (HIF) Prolyl Hydroxylases
- (2013) Rasheduzzaman Chowdhury et al. ACS Chemical Biology
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- Hairless is a histone H3K9 demethylase
- (2013) Liang Liu et al. FASEB JOURNAL
- Short Hairpin RNA Gene Silencing of Prolyl Hydroxylase-2 with a Minicircle Vector Improves Neovascularization of Hindlimb Ischemia
- (2013) Maarten A. Lijkwan et al. HUMAN GENE THERAPY
- The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition
- (2013) Elias H. Barriga et al. JOURNAL OF CELL BIOLOGY
- Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
- (2013) Michael H. Rabinowitz JOURNAL OF MEDICINAL CHEMISTRY
- Plasticity of Renal Erythropoietin-Producing Cells Governs Fibrosis
- (2013) T. Souma et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Hypoxia-Inducible Factor-1 Causes Renal Cyst Expansion through Calcium-Activated Chloride Secretion
- (2013) B. Buchholz et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The safety and efficacy of peginesatide in patients with CKD
- (2013) Kai-Uwe Eckardt Nature Reviews Nephrology
- JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1–mediated chromatin response to DNA breaks
- (2013) Sugiko Watanabe et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- How important is transfusion avoidance in 2013?
- (2013) I. C. Macdougall et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Peginesatide for Anemia in Patients with Chronic Kidney Disease Not Receiving Dialysis
- (2013) Iain C. Macdougall et al. NEW ENGLAND JOURNAL OF MEDICINE
- Peginesatide in Patients with Anemia Undergoing Hemodialysis
- (2013) Steven Fishbane et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulation of IL-1 -induced NF- B by hydroxylases links key hypoxic and inflammatory signaling pathways
- (2013) C. C. Scholz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis
- (2012) A. Laitala et al. BLOOD
- The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
- (2012) Erinn B. Rankin et al. CELL
- The New FDA Labeling for ESA--Implications for Patients and Providers
- (2012) B. J. Manns et al. Clinical Journal of the American Society of Nephrology
- Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis
- (2012) Qingdu Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Myeloid Cell-Derived Hypoxia-Inducible Factor Attenuates Inflammation in Unilateral Ureteral Obstruction-Induced Kidney Injury
- (2012) H. Kobayashi et al. JOURNAL OF IMMUNOLOGY
- Mechanisms of Anemia in CKD
- (2012) J. L. Babitt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Renal Tubular HIF-2α Expression Requires VHL Inactivation and Causes Fibrosis and Cysts
- (2012) Ruth E. Schietke et al. PLoS One
- Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
- (2012) K. Sarkar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anemia and Erythrocytosis in patients after kidney transplantation
- (2012) Jolanta Malyszko et al. TRANSPLANT INTERNATIONAL
- Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
- (2012) Gregg L. Semenza TRENDS IN MOLECULAR MEDICINE
- Notice
- (2012) Kidney International Supplements
- Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
- (2011) Chia Chi Sun et al. AMERICAN JOURNAL OF HEMATOLOGY
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension
- (2011) J. Bond et al. BLOOD
- Inhibition of 2-oxoglutarate dependent oxygenases
- (2011) Nathan R. Rose et al. CHEMICAL SOCIETY REVIEWS
- Hypoxia Is Present in Murine Atherosclerotic Plaques and Has Multiple Adverse Effects on Macrophage Lipid Metabolism
- (2011) Sajesh Parathath et al. CIRCULATION RESEARCH
- Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner
- (2011) Chih-Kang Chiang et al. LABORATORY INVESTIGATION
- Specific Contribution of the Erythropoietin Gene 3' Enhancer to Hepatic Erythropoiesis after Late Embryonic Stages
- (2011) N. Suzuki et al. MOLECULAR AND CELLULAR BIOLOGY
- The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
- (2011) Z. Wang et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism
- (2010) Na Zhang et al. Cell Metabolism
- Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
- (2010) Ming Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
- (2010) Michele M. Hickey et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD
- (2010) W. M. Bernhardt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders
- (2010) C. M. Beall et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
- (2010) Y. A. Minamishima et al. SCIENCE
- Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude
- (2010) X. Yi et al. SCIENCE
- Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin
- (2009) D. R. Ashby et al. HAEMATOLOGICA
- Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease
- (2009) Damien R. Ashby et al. KIDNEY INTERNATIONAL
- Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney
- (2009) Y. R. Song et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- A Peptide-Based Erythropoietin-Receptor Agonist for Pure Red-Cell Aplasia
- (2009) Iain C. Macdougall et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease
- (2009) Marc A. Pfeffer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Evidence for a Lack of a Direct Transcriptional Suppression of the Iron Regulatory Peptide Hepcidin by Hypoxia-Inducible Factors
- (2009) Melanie Volke et al. PLoS One
- Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model
- (2009) W. M. Bernhardt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis
- (2008) M. J. Percy et al. BLOOD
- Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
- (2008) N. Obara et al. BLOOD
- Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 mutation
- (2008) D. P. Gale et al. BLOOD
- Anemia of chronic disease: A harmful disorder or an adaptive, beneficial response?
- (2008) R. Zarychanski et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
- (2008) Ian J Frew et al. EMBO JOURNAL
- The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
- (2008) Sophie Beyer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury
- (2008) P. Hill et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- The Effect of Altitude on Dosing and Response to Erythropoietin in ESRD
- (2008) M. A. Brookhart et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
- (2008) Julián Aragonés et al. NATURE GENETICS
- A Gain-of-Function Mutation in theHIF2AGene in Familial Erythrocytosis
- (2008) Melanie J. Percy et al. NEW ENGLAND JOURNAL OF MEDICINE
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