The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment

Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors

(2011) Ya-Min Tian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Dose Epoetin Beta in the First Weeks Following Renal Transplantation and Delayed Graft Function: Results of the Neo-PDGF Study

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Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD

(2010) W. M. Bernhardt et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing

(2009) James D. Webb et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Application of a Proteolysis/Mass Spectrometry Method for Investigating the Effects of Inhibitors on Hydroxylase Structure

(2009) Christopher J. Stubbs et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

(2009) Alexander Paliege et al.   KIDNEY INTERNATIONAL

Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model

(2009) W. M. Bernhardt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivofunctions of the prolyl-4-hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues

(2008) D. M. Katschinski   Acta Physiologica

Physiological basis for the use of erythropoietin in critically ill patients at risk for acute kidney injury

(2008) Wanja M Bernhardt et al.   Current Opinion in Critical Care

Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury

(2008) P. Hill et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

HIF Activation Protects From Acute Kidney Injury

(2008) A. Weidemann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney

(2008) C. Rosenberger et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The RIFLE criteria and mortality in acute kidney injury: A systematic review

(2007) Z. Ricci et al.   KIDNEY INTERNATIONAL