Harwinder Sidhu

United States Research

论文

评论了 Fetal bovine serum (FBS): Past – present – future
FBS poses ethical concerns because of how and from where it is derived. This article discusses alternatives such as serum-free media and organ-on-chip technology. I believe the organ on a chip technology can be a really great alternative!

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评论了 Effect of particle size distribution on filtration performance of cell culture medium
Thia article primarily discusses the key particle size range for filter sterilization of CHO media to avoid microbial contamination.

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评论了 TGF-beta signalling in colon carcinogenesis
TGF beta pathway is of interest in many types of cancers but the exact role it has to play is not yet fully understood.

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评论了 Zinc as a complementary treatment for cancer patients: a systematic review
Interesting that Zinc is able to counter the side effects of popular cancer treatments such as chemotherapy or radiotherapy-induced inflammation!

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评论了 Drinking “Vodka” or vodka – This is a question
Vodka is more toxic than ethanol but seemingly less toxic than French Brandy! I would still say no to vodka based on the cell viability results.

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评论了 How to tell whether that whiskey is fake
Interesting use of fluorescent dyes to distinguish fake alcohol. German scientists in this article came up[ with fluorescent dyes that can distinguish fae alcohol from already existing known alcohol sample. I can almost see this becoming an alcohol testing kit and being sold on Amazon!

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评论了 The effects of cigarette smoking on the female voice
I wonder if smoking, especially nicotine, makes you a better singer. While the majority of singers abstain from it, saying this ruins their vocal cords, there are exceptions who think that smoking makes their voice deeper (Adele comes to mind!). More research is needed in this regard.

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评论了 Severe Combined ImmunoDeficient (SCID) mice in biomedical research
SCID mice, specifically CB17 SCID, lack T and B cells due to a fault in DNA repair thus making it easier for them to accept xenogenic cells.

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评论了 Male C57BL6/N and C57BL6/J Mice Respond Differently to Constant Light and Running-Wheel Access
The differences are probably due to the difference in genetic mutations in each mouse and what those mutations affect. For example, the mutation present in C57Bl6/J mice affects its metabolism while the C57bl6/N mice do not have this issue. There could be a number of other reasons as well such as breeding method, vendor, any environmental impact, etc.

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评论了 Brain Inflammation in the ApcMin/+ Mouse Model of Colon Cancer
Interesting paper demonstrating elevated inflammatory cytokines in the brain following colon cancer in mice.

期刊

评论了 Mobile DNA
The content is really good as well!!

期刊

评论了 Mobile DNA
Interesting name!

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评论了 Happiness is…
There is no content here lol! Happiness is .....

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评论了 Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice
Graft vs host disease is a concern. Often times the mice are euthanized due to not tolerating the xenograft well.

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评论了 Metastatic Cancer Cell
Couldn't read the entire article but it will be interesting to see how the cancer cells break away from their primary source/location; and how the tumor microenvironment facilitates this...