Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

(2014) A. K. Maiti et al.   HUMAN MOLECULAR GENETICS

Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-  in Lupus Patients In Vivo

(2014) S. N. Kariuki et al.   JOURNAL OF IMMUNOLOGY

Activation of the Interferon Pathway is Dependent Upon Autoantibodies in African-American SLE Patients, but Not in European-American SLE Patients

(2013) Kichul Ko et al.   Frontiers in Immunology

Recent insights into the genetic basis of systemic lupus erythematosus

(2012) Ornella Josephine Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

Variation in theICAM1–ICAM4–ICAM5locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

(2012) Kwangwoo Kim et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of Interferon-beta Responses in Multiple Sclerosis Immune Cells Associated With High-Dose Statins

(2012) Xuan Feng et al.   ARCHIVES OF NEUROLOGY

Gene-Expression-Guided Selection of Candidate Loci and Molecular Phenotype Analyses Enhance Genetic Discovery in Systemic Lupus Erythematosus

(2012) Yelena Koldobskaya et al.   Clinical & Developmental Immunology

Genetic Ancestry, Serum Interferon-  Activity, and Autoantibodies in Systemic Lupus Erythematosus

(2012) K. KO et al.   JOURNAL OF RHEUMATOLOGY

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

(2011) Elena Sánchez et al.   ARTHRITIS AND RHEUMATISM

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

(2011) B Namjou et al.   GENES AND IMMUNITY

Autoimmune Disease Risk Variant of IFIH1 Is Associated with Increased Sensitivity to IFN-  and Serologic Autoimmunity in Lupus Patients

(2011) T. Robinson et al.   JOURNAL OF IMMUNOLOGY

IFN-  Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1  and LFA-1

(2011) N. Hagberg et al.   JOURNAL OF IMMUNOLOGY

The Autoimmune Disease Risk Allele of UBE2L3 in African American Patients with Systemic Lupus Erythematosus: A Recessive Effect Upon Subphenotypes

(2011) S. AGIK et al.   JOURNAL OF RHEUMATOLOGY

Association of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete

(2011) E Eliopoulos et al.   LUPUS

Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

(2011) Sulaiman M Al-Mayouf et al.   NATURE GENETICS

Familial Aggregation of Autoimmune Disease in Juvenile Dermatomyositis

(2011) T. B. Niewold et al.   PEDIATRICS

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

(2010) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

Interferon Alpha in Systemic Lupus Erythematosus

(2010) Timothy B. Niewold et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus

(2010) Silvia N Kariuki et al.   ARTHRITIS RESEARCH & THERAPY

Association of IRF5 polymorphisms with activation of the interferon   pathway

(2009) O. J. Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

Phafin2 modulates the structure and function of endosomes by a Rab5-dependent mechanism

(2009) Wen-Jie Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis

(2009) Adriano Chiò et al.   HUMAN MOLECULAR GENETICS

Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus

(2009) M Petri et al.   LUPUS

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Protein Phosphatase 6 Regulatory Subunits Composed of Ankyrin Repeat Domains†

(2008) Bjarki Stefansson et al.   BIOCHEMISTRY

Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America

(2008) Roman Kosoy et al.   HUMAN MUTATION

Interferon Alpha-Induced Lupus

(2008) Timothy B. Niewold   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

EAPF/Phafin-2, a novel endoplasmic reticulum-associated protein, facilitates TNF-α-triggered cellular apoptosis through endoplasmic reticulum-mitochondrial apoptotic pathway

(2008) Changfei Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS