Interferon Alpha in Systemic Lupus Erythematosus

Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-  in Lupus Patients In Vivo

(2014) S. N. Kariuki et al.   JOURNAL OF IMMUNOLOGY

Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study

(2012) Marian Suarez-Gestal et al.   ARTHRITIS RESEARCH & THERAPY

Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists

(2010) D. Rajagopal et al.   BLOOD

Regulatory T cells and their molecular markers in peripheral blood of the patients with systemic lupus erythematosus

(2010) Shaoxian Hu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Neutralization of interferon-α/β-inducible genes and downstream effect in a phase I trial of an anti-interferon-α monoclonal antibody in systemic lupus erythematosus

(2009) Yihong Yao et al.   ARTHRITIS AND RHEUMATISM

Interferon-α treatment of female (NZW × BXSB)F1mice mimics some but not all features associated with theYaamutation

(2009) Meera Ramanujam et al.   ARTHRITIS AND RHEUMATISM

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: A validation study

(2009) Jason W. Bauer et al.   ARTHRITIS AND RHEUMATISM

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

Conserved anti-proliferative effect and poor inhibition of TNFα secretion by regulatory CD4+CD25+ T cells in patients with systemic lupus erythematosus

(2009) Jesús Gómez et al.   CLINICAL IMMUNOLOGY

Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations

(2009) J S Bates et al.   GENES AND IMMUNITY

Identification of new SLE-associated genes with a two-step Bayesian study design

(2009) D L Armstrong et al.   GENES AND IMMUNITY

Age- and gender-specific modulation of serum osteopontin and interferon-α by osteopontin genotype in systemic lupus erythematosus

(2009) S N Kariuki et al.   GENES AND IMMUNITY

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

Type I Interferon Signaling in Dendritic Cells Stimulates the Development of Lymph-Node-Resident T Follicular Helper Cells

(2009) Helena Cucak et al.   IMMUNITY

Interferon-alpha (IFN-α)–conditioned DC Preferentially Stimulate Type-1 and Limit Treg-type In Vitro T-cell Responses From RCC Patients

(2009) Margherita Gigante et al.   JOURNAL OF IMMUNOTHERAPY

Review of recent genome-wide association scans in lupus

(2009) R. R. Graham et al.   JOURNAL OF INTERNAL MEDICINE

Immunogenetic studies on systemic lupus erythematosus

(2009) GD Sebastiani et al.   LUPUS

Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus

(2009) M Petri et al.   LUPUS

Association study of a single nucleotide polymorphism in the exon 2 region of toll-like receptor 9 (TLR9) gene with susceptibility to systemic lupus erythematosus among Chinese

(2009) Chang-Juan Xu et al.   MOLECULAR BIOLOGY REPORTS

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

(2009) Isaac T. W. Harley et al.   NATURE REVIEWS GENETICS

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

(2009) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lack of association between the interferon-  signature and longitudinal changes in disease activity in systemic lupus erythematosus

(2008) C Landolt-Marticorena et al.   ANNALS OF THE RHEUMATIC DISEASES

STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk

(2008) A-K Abelson et al.   ANNALS OF THE RHEUMATIC DISEASES

A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population

(2008) K Shimane et al.   ANNALS OF THE RHEUMATIC DISEASES

Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-α–producing antigen-presenting cells

(2008) Bing Yan et al.   ARTHRITIS AND RHEUMATISM

Age‐ and sex‐related patterns of serum interferon‐α activity in lupus families

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro–positive mothers of children with neonatal lupus

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Association ofIRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: Support for a crucial role of intron 1 polymorphisms

(2008) Aya Kawasaki et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Reduced CD4+,CD25− T cell sensitivity to the suppressive function of CD4+,CD25high,CD127−/lowregulatory T cells in patients with active systemic lupus erythematosus

(2008) Ram Kumar Chowdary Venigalla et al.   ARTHRITIS AND RHEUMATISM

Interferon-α and viral triggers promote functional maturation of human monocyte-derived dendritic cells

(2008) A. Farkas et al.   BRITISH JOURNAL OF DERMATOLOGY

Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis

(2008) J. Yates et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history

(2008) P FITZGERALDBOCARSLY et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Yaaautoimmune phenotypes are conferred by overexpression of TLR7

(2008) Anna‐Marie Fairhurst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans

(2008) J A Kelly et al.   GENES AND IMMUNITY

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

(2008) S. Sigurdsson et al.   HUMAN MOLECULAR GENETICS

Altered homeostasis of CD4+ FoxP3+regulatory T-cell subpopulations in systemic lupus erythematosus

(2008) Jau-Ling Suen et al.   IMMUNOLOGY

Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)

(2008) M. Bonelli et al.   INTERNATIONAL IMMUNOLOGY

Interferon Alpha-Induced Lupus

(2008) Timothy B. Niewold   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Severe Systemic Lupus Erythematosus Induced by Antiviral Treatment for Hepatitis C

(2008) Vincent Ho et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

(2008) Robert R Graham et al.   NATURE GENETICS

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

(2008) Stacy L Musone et al.   NATURE GENETICS

The genetics of SLE: an update in the light of genome-wide association studies

(2008) B. Rhodes et al.   RHEUMATOLOGY

Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis

(2008) Young Ho Lee et al.   RHEUMATOLOGY INTERNATIONAL