Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

Multiple Lupus-AssociatedITGAMVariants Alter Mac-1 Functions on Neutrophils

(2013) Yebin Zhou et al.   ARTHRITIS AND RHEUMATISM

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

(2013) Julio E. Molineros et al.   PLoS Genetics

Variation in theICAM1–ICAM4–ICAM5locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries

(2012) Kwangwoo Kim et al.   ANNALS OF THE RHEUMATIC DISEASES

Thers1143679(R77H) lupus associated variant ofITGAM(CD11b) impairs complement receptor 3 mediated functions in human monocytes

(2012) Benjamin Rhodes et al.   ANNALS OF THE RHEUMATIC DISEASES

Gene network analysis of small molecules with autoimmune disease associated genes predicts a novel strategy for drug efficacy

(2012) Amit K. Maiti et al.   AUTOIMMUNITY REVIEWS

Human Lupus Serum Induces Neutrophil-Mediated Organ Damage in Mice That Is Enabled by Mac-1 Deficiency

(2012) F. Rosetti et al.   JOURNAL OF IMMUNOLOGY

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis

(2011) F. D. Carmona et al.   ANNALS OF THE RHEUMATIC DISEASES

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

(2011) Elena Sánchez et al.   ARTHRITIS AND RHEUMATISM

Alpha-actinin: A multidisciplinary protein with important role in B-cell driven autoimmunity

(2011) Katerina G. Oikonomou et al.   AUTOIMMUNITY REVIEWS

Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases

(2011) Juan-Manuel Anaya et al.   AUTOIMMUNITY REVIEWS

Regulation of chaperone gene expression by heat shock transcription factor inSaccharomyces cerevisiae: Importance in normal cell growth, stress resistance, and longevity

(2011) Hiroshi Sakurai et al.   FEBS LETTERS

A Systemic Lupus Erythematosus-associated R77H Substitution in the CD11b Chain of the Mac-1 Integrin Compromises Leukocyte Adhesion and Phagocytosis

(2011) Matthew MacPherson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of nucleic acid binding by a recombinant translin–trax complex

(2010) Matthew Lluis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ITGAM Arg77His Is Associated with Disease Susceptibility, Arthritis, and Renal Symptoms in Systemic Lupus Erythematosus Patients from a Sample of the Polish Population

(2010) Teresa Warchoł et al.   DNA AND CELL BIOLOGY

Differential Requirements of Hsp90 and DNA for the Formation of Estrogen Receptor Homodimers and Heterodimers

(2010) Emily Powell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Batf coordinates multiple aspects of B and T cell function required for normal antibody responses

(2010) Briana C. Betz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spatiotemporal Regulation of Heat Shock Protein 90-Chaperoned Self-DNA and CpG-Oligodeoxynucleotide for Type I IFN Induction via Targeting to Static Early Endosome

(2010) K. Okuya et al.   JOURNAL OF IMMUNOLOGY

Polymorphisms of the ITGAM Gene Confer Higher Risk of Discoid Cutaneous Than of Systemic Lupus Erythematosus

(2010) Tiina M. Järvinen et al.   PLoS One

HSP90 manages the ends

(2010) Diane C. DeZwaan et al.   TRENDS IN BIOCHEMICAL SCIENCES

ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

(2009) X. Kim-Howard et al.   ANNALS OF THE RHEUMATIC DISEASES

Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors

(2009) Marian Suarez-Gestal et al.   ARTHRITIS AND RHEUMATISM

Altered cell–cell and cell–matrix interactions in the development of systemic autoimmunity

(2009) Angelika Antoni et al.   AUTOIMMUNITY

Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression

(2009) Masae Ohno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

(2009) F. Tie et al.   DEVELOPMENT

Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression

(2009) Bin Zheng et al.   FEBS Journal

Admixture in Hispanic Americans: its impact on ITGAM association and implications for admixture mapping in SLE

(2009) J E Molineros et al.   GENES AND IMMUNITY

ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai

(2009) Wanling Yang et al.   HUMAN MOLECULAR GENETICS

Evaluation of imputation-based association in and around the integrin- -M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE)

(2009) S. Han et al.   HUMAN MOLECULAR GENETICS

Identification of a heat shock-responsive cis-acting DNA sequence and its transcriptional regulator: Their roles in the expression of the Spirulina-desD gene in response to heat stress

(2009) Pavinee Kurdrid et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

(2009) S. M. Mangsbo et al.   JOURNAL OF IMMUNOLOGY

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

Heat shock protein 90β: A novel mediator of vitamin D action

(2008) Giana Angelo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

catmap: Case-control And TDT Meta-Analysis Package

(2008) Kristin K Nicodemus   BMC BIOINFORMATICS

Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-α regulation

(2008) Pranoti Mandrekar et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

(2008) Swapan K Nath et al.   NATURE GENETICS

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility

(2008) Jacques Behmoaras et al.   NATURE GENETICS

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Association of Systemic Lupus Erythematosus withC8orf13–BLKandITGAM–ITGAX

(2008) Geoffrey Hom et al.   NEW ENGLAND JOURNAL OF MEDICINE