Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China

Mapping genetic variants in the CFH gene for association with leprosy in Han Chinese

(2014) D-F Zhang et al.   GENES AND IMMUNITY

No association between genetic variants of the LRRK2 gene and schizophrenia in Han Chinese

(2014) Xiao Li et al.   NEUROSCIENCE LETTERS

Inhibition of LRRK2 kinase activity stimulates macroautophagy

(2013) Claudia Manzoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Genetic variants of complement genes Ficolin-2, Mannose-binding lectin and Complement factor H are associated with leprosy in Han Chinese from Southwest China

(2013) Deng-Feng Zhang et al.   HUMAN GENETICS

Interplay of LRRK2 with chaperone-mediated autophagy

(2013) Samantha J Orenstein et al.   NATURE NEUROSCIENCE

No association of the LRRK2 genetic variants with Alzheimer's disease in Han Chinese individuals

(2013) Rui Bi et al.   NEUROBIOLOGY OF AGING

LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations

(2013) Patrick Marcinek et al.   PLoS One

ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression

(2013) Yuangang Zhu et al.   Protein & Cell

The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway

(2012) José M. Bravo-San Pedro et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China

(2012) Dong Wang et al.   HUMAN GENETICS

Genetic and Immunological Evidence Implicates Interleukin 6 as a Susceptibility Gene for Leprosy Type 2 Reaction

(2012) Ana Lucia M. Sousa et al.   JOURNAL OF INFECTIOUS DISEASES

LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

(2012) M. S. Moehle et al.   JOURNAL OF NEUROSCIENCE

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

(2012) Youren Tong et al.   Molecular Neurodegeneration

Mitochondrial DNA Copy Number, but Not Haplogroup, Confers a Genetic Susceptibility to Leprosy in Han Chinese from Southwest China

(2012) Dong Wang et al.   PLoS One

LRRK2 and Human Disease: A Complicated Question or a Question of Complexes?

(2012) P. A. Lewis et al.   Science Signaling

Interleukin 4-590T/C Polymorphism and Susceptibility to Leprosy

(2011) Degang Yang et al.   Genetic Testing and Molecular Biomarkers

TNF -308G>A Single Nucleotide Polymorphism Is Associated With Leprosy Among Brazilians: A Genetic Epidemiology Assessment, Meta-Analysis, and Functional Study

(2011) Cynthia C. Cardoso et al.   JOURNAL OF INFECTIOUS DISEASES

Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease

(2011) Alan S. L. Wong et al.   NATURE CELL BIOLOGY

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

(2011) Zhihua Liu et al.   NATURE IMMUNOLOGY

IFNG +874 T>A single nucleotide polymorphism is associated with leprosy among Brazilians

(2010) C. C. Cardoso et al.   HUMAN GENETICS

Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes

(2010) Bishwa R. Sapkota et al.   HUMAN IMMUNOLOGY

LRRK2 Is Involved in the IFN-  Response and Host Response to Pathogens

(2010) A. Gardet et al.   JOURNAL OF IMMUNOLOGY

Leprosy and the Human Genome

(2010) E. A. Misch et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect

(2010) Donglai Sheng et al.   PLoS Genetics

Treatment of leprosy/Hansen's disease in the early 21st century

(2009) Sophie M. Worobec   Dermatologic Therapy

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

(2009) Andrea Alter et al.   HUMAN GENETICS

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

(2009) Javier Alegre-Abarrategui et al.   HUMAN MOLECULAR GENETICS

LRRK2 Modulates Vulnerability to Mitochondrial Dysfunction in Caenorhabditis elegans

(2009) S. Saha et al.   JOURNAL OF NEUROSCIENCE

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

The WD40 Domain Is Required for LRRK2 Neurotoxicity

(2009) Nathan D. Jorgensen et al.   PLoS One

Pathogenesis of Parkinson's disease: emerging role of molecular chaperones

(2009) Rina Bandopadhyay et al.   TRENDS IN MOLECULAR MEDICINE

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

(2008) Edward D. Plowey et al.   JOURNAL OF NEUROCHEMISTRY

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS