LRRK2 and RIPK2 Variants in the NOD 2-Mediated Signaling Pathway Are Associated with Susceptibility to Mycobacterium leprae in Indian Populations

Genetic evidence of TAP1 gene variant as a susceptibility factor in Indian leprosy patients

(2013) Vidyagouri Shinde et al.   HUMAN IMMUNOLOGY

The role of LRRK2 in inflammatory bowel disease

(2012) Zhihua Liu et al.   CELL RESEARCH

Polymorphisms of NOD2 and the risk of tuberculosis: a validation study in the Chinese population

(2012) H. Pan et al.   International Journal of Immunogenetics

Crohn's Disease Susceptibility Genes are Associated With Leprosy in the Vietnamese Population

(2012) A. V. Grant et al.   JOURNAL OF INFECTIOUS DISEASES

Nucleotide-binding oligomerization domain 2 (Nod2) is dispensable for the innate immune responses of macrophages against Yersinia enterocolitica

(2012) Yu-Jin Jeong et al.   JOURNAL OF MICROBIOLOGY

NOD2 triggers an interleukin-32–dependent human dendritic cell program in leprosy

(2012) Mirjam Schenk et al.   NATURE MEDICINE

Genetic Evidence of Functional Ficolin-2 Haplotype as Susceptibility Factor in Cutaneous Leishmaniasis

(2012) Amal Assaf et al.   PLoS One

LRRK2 and Human Disease: A Complicated Question or a Question of Complexes?

(2012) P. A. Lewis et al.   Science Signaling

Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease

(2012) Byoung Dae Lee et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pathogen-Mediated Proteolysis of the Cell Death Regulator RIPK1 and the Host Defense Modulator RIPK2 in Human Aortic Endothelial Cells

(2012) Andrés G. Madrigal et al.   PLoS Pathogens

The Role of Intracellular Receptor NODs for Cytokine Production by Macrophages Infected withMycobacterium leprae

(2012) Tae Jin Kang et al.   Immune Network

Gene expression analysis of leprosy by using a multiplex branched DNA assay

(2011) Yonghu Sun et al.   EXPERIMENTAL DERMATOLOGY

Combined promoter haplotypes of the IL10R genes are associated with protection against severe malaria in Gabonese children

(2011) T. P. Velavan et al.   IMMUNOGENETICS

Human genetic susceptibility to intracellular pathogens

(2011) Fredrik O. Vannberg et al.   IMMUNOLOGICAL REVIEWS

Meta-analysis of published studies identified eight additional common susceptibility loci for Crohnʼs disease and ulcerative colitis

(2011) Junji Umeno et al.   INFLAMMATORY BOWEL DISEASES

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

(2011) Mansoureh Hakimi et al.   JOURNAL OF NEURAL TRANSMISSION

Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy

(2011) Furen Zhang et al.   NATURE GENETICS

Ficolin-2 Levels and FCN2 Haplotypes Influence Hepatitis B Infection Outcome in Vietnamese Patients

(2011) Hoang V. Tong et al.   PLoS One

LRRK2 Is Involved in the IFN-  Response and Host Response to Pathogens

(2010) A. Gardet et al.   JOURNAL OF IMMUNOLOGY

Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis

(2009) Ikuo Okafuji et al.   ARTHRITIS AND RHEUMATISM

NOD2-associated diseases: Bridging innate immunity and autoinflammation

(2009) Arturo Borzutzky et al.   CLINICAL IMMUNOLOGY

Reconstructing Indian population history

(2009) David Reich et al.   NATURE

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

(2009) Marc Monot et al.   NATURE GENETICS

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Common Genetic Fingerprint in Leprosy and Crohn's Disease?

(2009) Erwin Schurr et al.   NEW ENGLAND JOURNAL OF MEDICINE

The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

(2008) Lilian O. Moreira et al.   CELLULAR MICROBIOLOGY

The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

(2008) Osamu Hitotsumatsu et al.   IMMUNITY