Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

(2018) Eduardo Reátegui et al.   Nature Communications

Drinking problems: mechanisms of macropinosome formation and maturation

(2017) Catherine M. Buckley et al.   FEBS Journal

The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2

(2017) Jaekwang Jeong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular uptake of extracellular vesicles is mediated by clathrin-independent endocytosis and macropinocytosis

(2017) Helena Costa Verdera et al.   JOURNAL OF CONTROLLED RELEASE

Mechanistic principles underlying regulation of the actin cytoskeleton by phosphoinositides

(2017) Yosuke Senju et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell–Cell Contact and Receptor Tyrosine Kinase Signaling

(2017) Christine Chiasson-MacKenzie et al.   Cold Spring Harbor Perspectives in Biology

Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein

(2017) Laura A. Laviolette et al.   Nature Communications

Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles

(2017) Erik Bernitt et al.   Nature Communications

Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes

(2016) Ashim Rai et al.   CELL

Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus

(2016) Nadia Jaber et al.   JOURNAL OF CELL SCIENCE

Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways

(2016) Seong M. Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

(2016) Shawn M Davidson et al.   NATURE MEDICINE

Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking

(2016) Chiara Francavilla et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking

(2016) Chiara Francavilla et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A plasma membrane template for macropinocytic cups

(2016) Douwe M Veltman et al.   eLife

Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein

(2015) J. J. Kamphorst et al.   CANCER RESEARCH

NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin

(2015) Christine Chiasson-MacKenzie et al.   JOURNAL OF CELL BIOLOGY

Role of Merlin/NF2 inactivation in tumor biology

(2015) A M Petrilli et al.   ONCOGENE

Schwann Cell Myelination

(2015) James L. Salzer   Cold Spring Harbor Perspectives in Biology

Active macropinocytosis induction by stimulation of epidermal growth factor receptor and oncogenic Ras expression potentiates cellular uptake efficacy of exosomes

(2015) Ikuhiko Nakase et al.   Scientific Reports

Neurofibromin controls macropinocytosis and phagocytosis in Dictyostelium

(2015) Gareth Bloomfield et al.   eLife

PIP3-dependent macropinocytosis is incompatible with chemotaxis

(2014) Douwe M. Veltman et al.   JOURNAL OF CELL BIOLOGY

ERM proteins at a glance

(2014) Andrea I. McClatchey   JOURNAL OF CELL SCIENCE

Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis

(2014) M. Maekawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The EGFR Family: Not So Prototypical Receptor Tyrosine Kinases

(2014) M. A. Lemmon et al.   Cold Spring Harbor Perspectives in Biology

Preferential invasion of mitotic cells by Salmonella reveals that cell surface cholesterol is maximal during metaphase

(2013) A. J. M. Santos et al.   JOURNAL OF CELL SCIENCE

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Advances in the treatment of neurofibromatosis-associated tumours

(2013) Andrew L. Lin et al.   Nature Reviews Clinical Oncology

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Ezrin/Radixin/Moesin Proteins and Flotillins Cooperate to Promote Uropod Formation in T Cells

(2013) Sibylla Martinelli et al.   Frontiers in Immunology

Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules

(2012) Kripa Gowrishankar et al.   CELL

Merlin/ERM proteins establish cortical asymmetry and centrosome position

(2012) A. M. Hebert et al.   GENES & DEVELOPMENT

Quantitation of the Effect of ErbB2 on Epidermal Growth Factor Receptor Binding and Dimerization

(2012) Yu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V

(2012) C. Schmees et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane mechanisms for signal transduction: The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes

(2012) Akihiro Kusumi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation from within: the cytoskeleton in transmembrane signaling

(2012) Khuloud Jaqaman et al.   TRENDS IN CELL BIOLOGY

Mechanical feedback between membrane tension and dynamics

(2012) Nils C. Gauthier et al.   TRENDS IN CELL BIOLOGY

Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation

(2012) Anna Sukhanova et al.   Cancer Discovery

The NF2 Tumor Suppressor, Merlin, Regulates Epidermal Development through the Establishment of a Junctional Polarity Complex

(2010) Andrew B. Gladden et al.   DEVELOPMENTAL CELL

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

The molecular physiology of activity-dependent bulk endocytosis of synaptic vesicles

(2009) Emma L. Clayton et al.   JOURNAL OF NEUROCHEMISTRY

Population context determines cell-to-cell variability in endocytosis and virus infection

(2009) Berend Snijder et al.   NATURE

Virus entry by macropinocytosis

(2009) Jason Mercer et al.   NATURE CELL BIOLOGY

Defining Macropinocytosis

(2009) Markus C. Kerr et al.   TRAFFIC

Get round and stiff for mitosis

(2008) Manuel Théry et al.   HFSP Journal

Cholesterol Accumulation by Macrophages Impairs Phagosome Maturation

(2008) Kassidy K. Huynh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shaping cups into phagosomes and macropinosomes

(2008) Joel A. Swanson   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth

(2007) Marianne F. James et al.   NEUROBIOLOGY OF DISEASE

Prolonged EGFR Signaling by ERBB2-Mediated Sequestration at the Plasma Membrane

(2007) Martin Offterdinger et al.   TRAFFIC